BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

810 related articles for article (PubMed ID: 11248085)

  • 1. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity.
    Staudinger JL; Goodwin B; Jones SA; Hawkins-Brown D; MacKenzie KI; LaTour A; Liu Y; Klaassen CD; Brown KK; Reinhard J; Willson TM; Koller BH; Kliewer SA
    Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3369-74. PubMed ID: 11248085
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
    Staudinger J; Liu Y; Madan A; Habeebu S; Klaassen CD
    Drug Metab Dispos; 2001 Nov; 29(11):1467-72. PubMed ID: 11602523
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pregnane X receptor mediated-transcription regulation of CYP3A by glycyrrhizin: a possible mechanism for its hepatoprotective property against lithocholic acid-induced injury.
    Wang YG; Zhou JM; Ma ZC; Li H; Liang QD; Tan HL; Xiao CR; Zhang BL; Gao Y
    Chem Biol Interact; 2012 Oct; 200(1):11-20. PubMed ID: 22982774
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice.
    Teng S; Piquette-Miller M
    J Pharmacol Exp Ther; 2005 Feb; 312(2):841-8. PubMed ID: 15456840
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of cyp3a gene transcription by the pregnane x receptor.
    Goodwin B; Redinbo MR; Kliewer SA
    Annu Rev Pharmacol Toxicol; 2002; 42():1-23. PubMed ID: 11807162
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
    Zhang J; Huang W; Qatanani M; Evans RM; Moore DD
    J Biol Chem; 2004 Nov; 279(47):49517-22. PubMed ID: 15358766
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics.
    LeCluyse EL
    Chem Biol Interact; 2001 May; 134(3):283-9. PubMed ID: 11336976
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor.
    Kliewer SA; Willson TM
    J Lipid Res; 2002 Mar; 43(3):359-64. PubMed ID: 11893771
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.
    Anakk S; Kalsotra A; Kikuta Y; Huang W; Zhang J; Staudinger JL; Moore DD; Strobel HW
    Pharmacogenomics J; 2004; 4(2):91-101. PubMed ID: 14770174
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.
    Xie W; Radominska-Pandya A; Shi Y; Simon CM; Nelson MC; Ong ES; Waxman DJ; Evans RM
    Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3375-80. PubMed ID: 11248086
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nuclear xeno-sensors as receptors for cholestatic bile acids: the second line of defense.
    Bock HH; Lammert F
    Hepatology; 2002 Jan; 35(1):232-4. PubMed ID: 11786981
    [No Abstract]   [Full Text] [Related]  

  • 12. Expression of PXR, CYP3A and MDR1 genes in liver of zebrafish.
    Bresolin T; de Freitas Rebelo M; Celso Dias Bainy A
    Comp Biochem Physiol C Toxicol Pharmacol; 2005; 140(3-4):403-7. PubMed ID: 15914091
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intestinal detoxification limits the activation of hepatic pregnane X receptor by lithocholic acid.
    Owen BM; Milona A; van Mil S; Clements P; Holder J; Boudjelal M; Cairns W; Parker M; White R; Williamson C
    Drug Metab Dispos; 2010 Jan; 38(1):143-9. PubMed ID: 19797606
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues.
    Matheny CJ; Ali RY; Yang X; Pollack GM
    Drug Metab Dispos; 2004 Sep; 32(9):1008-14. PubMed ID: 15319343
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor.
    Nallani SC; Goodwin B; Maglich JM; Buckley DJ; Buckley AR; Desai PB
    Drug Metab Dispos; 2003 May; 31(5):681-4. PubMed ID: 12695359
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Postnatal expression and induction by pregnenolone-16alpha-carbonitrile of the organic anion-transporting polypeptide 2 in rat liver.
    Guo GL; Johnson DR; Klaassen CD
    Drug Metab Dispos; 2002 Mar; 30(3):283-8. PubMed ID: 11854146
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis.
    Teng S; Piquette-Miller M
    Br J Pharmacol; 2007 Jun; 151(3):367-76. PubMed ID: 17435798
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
    Xu DX; Wei W; Sun MF; Wu CY; Wang JP; Wei LZ; Zhou CF
    Free Radic Biol Med; 2004 Jul; 37(1):10-22. PubMed ID: 15183191
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.
    Kliewer SA; Goodwin B; Willson TM
    Endocr Rev; 2002 Oct; 23(5):687-702. PubMed ID: 12372848
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution.
    Jones SA; Moore LB; Shenk JL; Wisely GB; Hamilton GA; McKee DD; Tomkinson NC; LeCluyse EL; Lambert MH; Willson TM; Kliewer SA; Moore JT
    Mol Endocrinol; 2000 Jan; 14(1):27-39. PubMed ID: 10628745
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.