446 related articles for article (PubMed ID: 11250914)
1. Minireview: 11beta-hydroxysteroid dehydrogenase type 1- a tissue-specific amplifier of glucocorticoid action.
Seckl JR; Walker BR
Endocrinology; 2001 Apr; 142(4):1371-6. PubMed ID: 11250914
[TBL] [Abstract][Full Text] [Related]
2. 11beta-Hydroxysteroid dehydrogenase in the brain: a novel regulator of glucocorticoid action?
Seckl JR
Front Neuroendocrinol; 1997 Jan; 18(1):49-99. PubMed ID: 9000459
[TBL] [Abstract][Full Text] [Related]
3. 11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action.
Chapman K; Holmes M; Seckl J
Physiol Rev; 2013 Jul; 93(3):1139-206. PubMed ID: 23899562
[TBL] [Abstract][Full Text] [Related]
4. Medical and physiological aspects of the 11beta-hydroxysteroid dehydrogenase system.
Seckl JR; Chapman KE
Eur J Biochem; 1997 Oct; 249(2):361-4. PubMed ID: 9370341
[TBL] [Abstract][Full Text] [Related]
5. Intracellular regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase (11beta-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: analysis of 11beta-HSD-1-deficient mice.
Harris HJ; Kotelevtsev Y; Mullins JJ; Seckl JR; Holmes MC
Endocrinology; 2001 Jan; 142(1):114-20. PubMed ID: 11145573
[TBL] [Abstract][Full Text] [Related]
6. 11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress.
Kotelevtsev Y; Holmes MC; Burchell A; Houston PM; Schmoll D; Jamieson P; Best R; Brown R; Edwards CR; Seckl JR; Mullins JJ
Proc Natl Acad Sci U S A; 1997 Dec; 94(26):14924-9. PubMed ID: 9405715
[TBL] [Abstract][Full Text] [Related]
7. Growth hormone, insulin-like growth factor-I and the cortisol-cortisone shuttle.
Stewart PM; Toogood AA; Tomlinson JW
Horm Res; 2001; 56 Suppl 1():1-6. PubMed ID: 11786677
[TBL] [Abstract][Full Text] [Related]
8. Phenotypic analysis of mice bearing targeted deletions of 11beta-hydroxysteroid dehydrogenases 1 and 2 genes.
Holmes MC; Kotelevtsev Y; Mullins JJ; Seckl JR
Mol Cell Endocrinol; 2001 Jan; 171(1-2):15-20. PubMed ID: 11165006
[TBL] [Abstract][Full Text] [Related]
9. 11beta-hydroxysteroid dehydrogenase is a predominant reductase in intact rat Leydig cells.
Leckie CM; Welberg LA; Seckl JR
J Endocrinol; 1998 Nov; 159(2):233-8. PubMed ID: 9795363
[TBL] [Abstract][Full Text] [Related]
10. The 11beta-hydroxysteroid dehydrogenases: functions and physiological effects.
Krozowski Z
Mol Cell Endocrinol; 1999 May; 151(1-2):121-7. PubMed ID: 10411326
[TBL] [Abstract][Full Text] [Related]
11. Distinct ontogeny of glucocorticoid and mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase types I and II mRNAs in the fetal rat brain suggest a complex control of glucocorticoid actions.
Diaz R; Brown RW; Seckl JR
J Neurosci; 1998 Apr; 18(7):2570-80. PubMed ID: 9502816
[TBL] [Abstract][Full Text] [Related]
12. Distribution of glucocorticoid and mineralocorticoid receptors and 11beta-hydroxysteroid dehydrogenases in human and rat ocular tissues.
Stokes J; Noble J; Brett L; Phillips C; Seckl JR; O'Brien C; Andrew R
Invest Ophthalmol Vis Sci; 2000 Jun; 41(7):1629-38. PubMed ID: 10845579
[TBL] [Abstract][Full Text] [Related]
13. Pathophysiology of modulation of local glucocorticoid levels by 11beta-hydroxysteroid dehydrogenases.
Sandeep TC; Walker BR
Trends Endocrinol Metab; 2001 Dec; 12(10):446-53. PubMed ID: 11701343
[TBL] [Abstract][Full Text] [Related]
14. The role of 11beta-hydroxysteroid dehydrogenases in the brain.
Holmes MC; Seckl JR
Mol Cell Endocrinol; 2006 Mar; 248(1-2):9-14. PubMed ID: 16413106
[TBL] [Abstract][Full Text] [Related]
15. 11beta-hydroxysteroid dehydrogenases: changing glucocorticoid action.
Seckl JR
Curr Opin Pharmacol; 2004 Dec; 4(6):597-602. PubMed ID: 15525550
[TBL] [Abstract][Full Text] [Related]
16. The type I and type II 11beta-hydroxysteroid dehydrogenase enzymes.
Krozowski Z; Li KX; Koyama K; Smith RE; Obeyesekere VR; Stein-Oakley A; Sasano H; Coulter C; Cole T; Sheppard KE
J Steroid Biochem Mol Biol; 1999; 69(1-6):391-401. PubMed ID: 10419017
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a promising therapeutic target.
Wamil M; Seckl JR
Drug Discov Today; 2007 Jul; 12(13-14):504-20. PubMed ID: 17631244
[TBL] [Abstract][Full Text] [Related]
18. 7α-hydroxylation of dehydroepiandrosterone does not interfere with the activation of glucocorticoids by 11β-hydroxysteroid dehydrogenase in E(t)C cerebellar neurons.
Gottfried-Blackmore A; Jellinck PH; Vecchiarelli HA; Masheeb Z; Kaufmann M; McEwen BS; Bulloch K
J Steroid Biochem Mol Biol; 2013 Nov; 138():290-7. PubMed ID: 23851218
[TBL] [Abstract][Full Text] [Related]
19. Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments.
Yau JL; Noble J; Kenyon CJ; Hibberd C; Kotelevtsev Y; Mullins JJ; Seckl JR
Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4716-21. PubMed ID: 11274359
[TBL] [Abstract][Full Text] [Related]
20. Local amplification of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 and its role in the inflammatory response.
Chapman KE; Coutinho A; Gray M; Gilmour JS; Savill JS; Seckl JR
Ann N Y Acad Sci; 2006 Nov; 1088():265-73. PubMed ID: 17192572
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]