151 related articles for article (PubMed ID: 11258966)
1. Identification of a reactive metabolite of terbinafine: insights into terbinafine-induced hepatotoxicity.
Iverson SL; Uetrecht JP
Chem Res Toxicol; 2001 Feb; 14(2):175-81. PubMed ID: 11258966
[TBL] [Abstract][Full Text] [Related]
2. Identification of novel glutathione conjugates of terbinafine in liver microsomes and hepatocytes across species.
Patil A; Ladumor MK; Kamble SH; Johnson BM; Subramanian M; Sinz MW; Singh DK; Putlur S; Bhutani P; Ahire DS; Singh S
Xenobiotica; 2019 Dec; 49(12):1403-1413. PubMed ID: 30747549
[TBL] [Abstract][Full Text] [Related]
3. Terbinafine-associated hepatotoxicity.
Ajit C; Suvannasankha A; Zaeri N; Munoz SJ
Am J Med Sci; 2003 May; 325(5):292-5. PubMed ID: 12792250
[TBL] [Abstract][Full Text] [Related]
4. Bioactivation of phencyclidine in rat and human liver microsomes and recombinant P450 2B enzymes: evidence for the formation of a novel quinone methide intermediate.
Driscoll JP; Kornecki K; Wolkowski JP; Chupak L; Kalgutkar AS; O'Donnell JP
Chem Res Toxicol; 2007 Oct; 20(10):1488-97. PubMed ID: 17892269
[TBL] [Abstract][Full Text] [Related]
5. Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes.
Kang P; Dalvie D; Smith E; Zhou S; Deese A
Drug Metab Dispos; 2007 Jul; 35(7):1081-8. PubMed ID: 17403914
[TBL] [Abstract][Full Text] [Related]
6. Lamisil (terbinafine) toxicity: Determining pathways to bioactivation through computational and experimental approaches.
Barnette DA; Davis MA; Dang NL; Pidugu AS; Hughes T; Swamidass SJ; Boysen G; Miller GP
Biochem Pharmacol; 2018 Oct; 156():10-21. PubMed ID: 30076845
[TBL] [Abstract][Full Text] [Related]
7. Terbinafine-induced cholestatic liver disease.
Lazaros GA; Papatheodoridis GV; Delladetsima JK; Tassopoulos NC
J Hepatol; 1996 Jun; 24(6):753-6. PubMed ID: 8835752
[TBL] [Abstract][Full Text] [Related]
8. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.
Zhao SX; Dalvie DK; Kelly JM; Soglia JR; Frederick KS; Smith EB; Obach RS; Kalgutkar AS
Chem Res Toxicol; 2007 Nov; 20(11):1649-57. PubMed ID: 17907785
[TBL] [Abstract][Full Text] [Related]
9. Metabolic detoxification determines species differences in coumarin-induced hepatotoxicity.
Vassallo JD; Hicks SM; Daston GP; Lehman-McKeeman LD
Toxicol Sci; 2004 Aug; 80(2):249-57. PubMed ID: 15141102
[TBL] [Abstract][Full Text] [Related]
10. Terbinafine-induced prolonged cholestasis with reduction of interlobular bile ducts.
Mallat A; Zafrani ES; Metreau JM; Dhumeaux D
Dig Dis Sci; 1997 Jul; 42(7):1486-8. PubMed ID: 9246051
[TBL] [Abstract][Full Text] [Related]
11. Characterization of glutathione conjugates of reactive metabolites of 3'-hydroxyacetanilide, a nonhepatotoxic positional isomer of acetaminophen.
Rashed MS; Nelson SD
Chem Res Toxicol; 1989; 2(1):41-5. PubMed ID: 2519230
[TBL] [Abstract][Full Text] [Related]
12. Identification and characterization of the glutathione and N-acetylcysteine conjugates of (E)-2-propyl-2,4-pentadienoic acid, a toxic metabolite of valproic acid, in rats and humans.
Kassahun K; Farrell K; Abbott F
Drug Metab Dispos; 1991; 19(2):525-35. PubMed ID: 1676665
[TBL] [Abstract][Full Text] [Related]
13. Identification of intermediate pathways of 4-hydroxynonenal metabolism in the rat.
Alary J; Fernandez Y; Debrauwer L; Perdu E; Guéraud F
Chem Res Toxicol; 2003 Mar; 16(3):320-7. PubMed ID: 12641432
[TBL] [Abstract][Full Text] [Related]
14. New glutathione conjugate of pyrrolizidine alkaloids produced by human cytosolic enzyme-dependent reactions in vitro.
Muluneh F; Häkkinen MR; El-Dairi R; Pasanen M; Juvonen RO
Rapid Commun Mass Spectrom; 2018 Aug; 32(16):1344-1352. PubMed ID: 29788543
[TBL] [Abstract][Full Text] [Related]
15. Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: correlation to in vitro drug metabolism.
Madsen KG; Olsen J; Skonberg C; Hansen SH; Jurva U
Chem Res Toxicol; 2007 May; 20(5):821-31. PubMed ID: 17447796
[TBL] [Abstract][Full Text] [Related]
16. Identification of multi-S-substituted conjugates of hydroquinone by HPLC-coulometric electrode array analysis and mass spectroscopy.
Hill BA; Kleiner HE; Ryan EA; Dulik DM; Monks TJ; Lau SS
Chem Res Toxicol; 1993; 6(4):459-69. PubMed ID: 8374043
[TBL] [Abstract][Full Text] [Related]
17. Electrochemical oxidation of troglitazone: identification and characterization of the major reactive metabolite in liver microsomes.
Madsen KG; Grönberg G; Skonberg C; Jurva U; Hansen SH; Olsen J
Chem Res Toxicol; 2008 Oct; 21(10):2035-41. PubMed ID: 18788755
[TBL] [Abstract][Full Text] [Related]
18. Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission.
Kassahun K; Pearson PG; Tang W; McIntosh I; Leung K; Elmore C; Dean D; Wang R; Doss G; Baillie TA
Chem Res Toxicol; 2001 Jan; 14(1):62-70. PubMed ID: 11170509
[TBL] [Abstract][Full Text] [Related]
19. In vitro metabolism of tolcapone to reactive intermediates: relevance to tolcapone liver toxicity.
Smith KS; Smith PL; Heady TN; Trugman JM; Harman WD; Macdonald TL
Chem Res Toxicol; 2003 Feb; 16(2):123-8. PubMed ID: 12588182
[TBL] [Abstract][Full Text] [Related]
20. Characterization of thiol-conjugated metabolites of 2-propylpent-4-enoic acid (4-ene VPA), a toxic metabolite of valproic acid, by electrospray tandem mass spectrometry.
Tang W; Abbott FS
J Mass Spectrom; 1996 Aug; 31(8):926-36. PubMed ID: 8799319
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]