250 related articles for article (PubMed ID: 11259327)
1. Decreases in phenytoin hydroxylation activities catalyzed by liver microsomal cytochrome P450 enzymes in phenytoin-treated rats.
Yamazaki H; Komatsu T; Takemoto K; Saeki M; Minami Y; Kawaguchi Y; Shimada N; Nakajima M; Yokoi T
Drug Metab Dispos; 2001 Apr; 29(4 Pt 1):427-34. PubMed ID: 11259327
[TBL] [Abstract][Full Text] [Related]
2. Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: roles of cytochromes P450 2C9, 2C19, and 3A4.
Komatsu T; Yamazaki H; Asahi S; Gillam EM; Guengerich FP; Nakajima M; Yokoi T
Drug Metab Dispos; 2000 Nov; 28(11):1361-8. PubMed ID: 11038165
[TBL] [Abstract][Full Text] [Related]
3. Phenytoin metabolism by human cytochrome P450: involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation.
Cuttle L; Munns AJ; Hogg NA; Scott JR; Hooper WD; Dickinson RG; Gillam EM
Drug Metab Dispos; 2000 Aug; 28(8):945-50. PubMed ID: 10901705
[TBL] [Abstract][Full Text] [Related]
4. Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation.
Munns AJ; De Voss JJ; Hooper WD; Dickinson RG; Gillam EM
Chem Res Toxicol; 1997 Sep; 10(9):1049-58. PubMed ID: 9305589
[TBL] [Abstract][Full Text] [Related]
5. P450 2C18 catalyzes the metabolic bioactivation of phenytoin.
Kinobe RT; Parkinson OT; Mitchell DJ; Gillam EM
Chem Res Toxicol; 2005 Dec; 18(12):1868-75. PubMed ID: 16359177
[TBL] [Abstract][Full Text] [Related]
6. Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450.
Miller KK; Cai J; Ripp SL; Pierce WM; Rushmore TH; Prough RA
Drug Metab Dispos; 2004 Mar; 32(3):305-13. PubMed ID: 14977864
[TBL] [Abstract][Full Text] [Related]
7. Identification of catalase in human livers as a factor that enhances phenytoin dihydroxy metabolite formation by human liver microsomes.
Komatsu T; Yamazaki H; Nakajima M; Yokoi T
Biochem Pharmacol; 2002 Jun; 63(12):2081-90. PubMed ID: 12110367
[TBL] [Abstract][Full Text] [Related]
8. Interactions between folate metabolism, phenytoin metabolism, and liver microsomal cytochrome P450.
Billings RE
Drug Nutr Interact; 1984; 3(1):21-32. PubMed ID: 6510238
[TBL] [Abstract][Full Text] [Related]
9. Effect of phenobarbital and spironolactone treatment on the oxidative metabolism of antipyrine by rat liver microsomes.
Szakács T; Veres Z; Vereczkey L
Pol J Pharmacol; 2001; 53(1):11-9. PubMed ID: 11785906
[TBL] [Abstract][Full Text] [Related]
10. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
Yao HT; Wu YS; Chang YW; Hsieh HP; Chen WC; Lan SJ; Chen CT; Chao YS; Chang L; Sun HY; Yeh TK
Drug Metab Dispos; 2007 Jul; 35(7):1042-9. PubMed ID: 17403915
[TBL] [Abstract][Full Text] [Related]
11. Stereoselective inhibition of diphenylhydantoin metabolism by p-hydroxyphenyl-phenylhydantoin enantiomers in rats.
Huang JD; Hsieh CY
Chirality; 1991; 3(6):454-9. PubMed ID: 1812955
[TBL] [Abstract][Full Text] [Related]
12. Hydroxylation of 5,5-diphenylhydantoin (phenytoin) by dog liver microsomes.
Butler TC; Dudley KH; Mitchell GN; Johnson D
Arch Int Pharmacodyn Ther; 1977 Jul; 228(1):4-9. PubMed ID: 21639
[TBL] [Abstract][Full Text] [Related]
13. Role of the alanine at position 363 of cytochrome P450 2B2 in influencing the NADPH- and hydroperoxide-supported activities.
Hanna IH; Teiber JF; Kokones KL; Hollenberg PF
Arch Biochem Biophys; 1998 Feb; 350(2):324-32. PubMed ID: 9473308
[TBL] [Abstract][Full Text] [Related]
14. Human CYP2C-mediated stereoselective phenytoin hydroxylation in Japanese: difference in chiral preference of CYP2C9 and CYP2C19.
Yasumori T; Chen LS; Li QH; Ueda M; Tsuzuki T; Goldstein JA; Kato R; Yamazoe Y
Biochem Pharmacol; 1999 Jun; 57(11):1297-303. PubMed ID: 10230773
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of phenytoin hydroxylation in human liver microsomes by several selective serotonin re-uptake inhibitors.
Nelson MH; Birnbaum AK; Remmel RP
Epilepsy Res; 2001 Apr; 44(1):71-82. PubMed ID: 11255075
[TBL] [Abstract][Full Text] [Related]
16. Effects of freezing, thawing, and storage of human liver samples on the microsomal contents and activities of cytochrome P450 enzymes.
Yamazaki H; Inoue K; Turvy CG; Guengerich FP; Shimada T
Drug Metab Dispos; 1997 Feb; 25(2):168-74. PubMed ID: 9029047
[TBL] [Abstract][Full Text] [Related]
17. Effect of superoxide dismutase on hydroxylase activity and hydrogen peroxide formation in anthranilamide hydroxylation by a rat liver microsomal monooxygenase system.
Ohta Y; Ishiguro I; Naito J; Shinohara R
Biochem Int; 1984 May; 8(5):617-27. PubMed ID: 6477624
[TBL] [Abstract][Full Text] [Related]
18. Characterization of hydroxyl radical formation by microsomal enzymes using a water-soluble trap, terephthalate.
Mishin VM; Thomas PE
Biochem Pharmacol; 2004 Aug; 68(4):747-52. PubMed ID: 15276082
[TBL] [Abstract][Full Text] [Related]
19. Biotransformation of lithocholic acid by rat hepatic microsomes: metabolite analysis by liquid chromatography/mass spectrometry.
Deo AK; Bandiera SM
Drug Metab Dispos; 2008 Feb; 36(2):442-51. PubMed ID: 18039809
[TBL] [Abstract][Full Text] [Related]
20. Study of the stereoselectivity of the para-hydroxylation of diphenylhydantoin by the rat liver microsomal cytochrome P-450-dependent enzymes [proceedings].
Cavalier R; Toussaint A; Cumps J
Arch Int Physiol Biochim; 1978 May; 86(2):411-3. PubMed ID: 81000
[No Abstract] [Full Text] [Related]
[Next] [New Search]
