BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 11259835)

  • 1. Active secretion and enterocytic drug metabolism barriers to drug absorption.
    Wacher VJ; Salphati L; Benet LZ
    Adv Drug Deliv Rev; 2001 Mar; 46(1-3):89-102. PubMed ID: 11259835
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein.
    Zhang Y; Benet LZ
    Clin Pharmacokinet; 2001; 40(3):159-68. PubMed ID: 11327196
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery.
    Benet LZ; Izumi T; Zhang Y; Silverman JA; Wacher VJ
    J Control Release; 1999 Nov; 62(1-2):25-31. PubMed ID: 10518631
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Strategies to overcome simultaneous P-glycoprotein mediated efflux and CYP3A4 mediated metabolism of drugs.
    Patel J; Mitra AK
    Pharmacogenomics; 2001 Nov; 2(4):401-15. PubMed ID: 11722289
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interplay of metabolism and transport in determining oral drug absorption and gut wall metabolism: a simulation assessment using the "Advanced Dissolution, Absorption, Metabolism (ADAM)" model.
    Darwich AS; Neuhoff S; Jamei M; Rostami-Hodjegan A
    Curr Drug Metab; 2010 Nov; 11(9):716-29. PubMed ID: 21189140
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional interaction of intestinal CYP3A4 and P-glycoprotein.
    Kivistö KT; Niemi M; Fromm MF
    Fundam Clin Pharmacol; 2004 Dec; 18(6):621-6. PubMed ID: 15548232
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The drug efflux-metabolism alliance: biochemical aspects.
    Benet LZ; Cummins CL
    Adv Drug Deliv Rev; 2001 Oct; 50 Suppl 1():S3-11. PubMed ID: 11576692
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of intestinal CYP3A4 and P-glycoprotein on oral drug absorption--theoretical approach.
    Ito K; Kusuhara H; Sugiyama Y
    Pharm Res; 1999 Feb; 16(2):225-31. PubMed ID: 10100307
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Factors and dosage formulations affecting the solubility and bioavailability of P-glycoprotein substrate drugs.
    Murakami T; Bodor E; Bodor N
    Expert Opin Drug Metab Toxicol; 2021 May; 17(5):555-580. PubMed ID: 33703995
    [No Abstract]   [Full Text] [Related]  

  • 10. Intestinal efflux transporters and drug absorption.
    Murakami T; Takano M
    Expert Opin Drug Metab Toxicol; 2008 Jul; 4(7):923-39. PubMed ID: 18624680
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Application of Intestinal Epithelial Cells Differentiated from Human Induced Pluripotent Stem Cells for Studies of Prodrug Hydrolysis and Drug Absorption in the Small Intestine.
    Akazawa T; Yoshida S; Ohnishi S; Kanazu T; Kawai M; Takahashi K
    Drug Metab Dispos; 2018 Nov; 46(11):1497-1506. PubMed ID: 30135242
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intestinal drug transporters: in vivo function and clinical importance.
    Kunta JR; Sinko PJ
    Curr Drug Metab; 2004 Feb; 5(1):109-24. PubMed ID: 14965254
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intestinal transporters: enhanced absorption through P-glycoprotein-related drug interactions.
    Zakeri-Milani P; Valizadeh H
    Expert Opin Drug Metab Toxicol; 2014 Jun; 10(6):859-71. PubMed ID: 24708201
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.
    Cummins CL; Jacobsen W; Benet LZ
    J Pharmacol Exp Ther; 2002 Mar; 300(3):1036-45. PubMed ID: 11861813
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of expression/function of intestinal P-glycoprotein under disease states.
    Murakami T; Bodor E; Bodor N
    Expert Opin Drug Metab Toxicol; 2020 Jan; 16(1):59-78. PubMed ID: 31821048
    [No Abstract]   [Full Text] [Related]  

  • 16. Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5.
    Mouly SJ; Matheny C; Paine MF; Smith G; Lamba J; Lamba V; Pusek SN; Schuetz EG; Stewart PW; Watkins PB
    Clin Pharmacol Ther; 2005 Dec; 78(6):605-18. PubMed ID: 16338276
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.
    Yu XY; Lin SG; Zhou ZW; Chen X; Liang J; Liu PQ; Duan W; Chowbay B; Wen JY; Li CG; Zhou SF
    Curr Drug Metab; 2007 May; 8(4):325-40. PubMed ID: 17504222
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model.
    Cao X; Gibbs ST; Fang L; Miller HA; Landowski CP; Shin HC; Lennernas H; Zhong Y; Amidon GL; Yu LX; Sun D
    Pharm Res; 2006 Aug; 23(8):1675-86. PubMed ID: 16841194
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The pharmacological role of P-glycoprotein in the intestinal epithelium.
    Van Asperen J; Van Tellingen O; Beijnen JH
    Pharmacol Res; 1998 Jun; 37(6):429-35. PubMed ID: 9695116
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Commonly used surfactant, Tween 80, improves absorption of P-glycoprotein substrate, digoxin, in rats.
    Zhang H; Yao M; Morrison RA; Chong S
    Arch Pharm Res; 2003 Sep; 26(9):768-72. PubMed ID: 14560928
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.