BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 11266177)

  • 1. The C4 hydroxyl group of phorbol esters is not necessary for protein kinase C binding.
    Tanaka M; Irie K; Nakagawa Y; Nakamura Y; Ohigashi H; Wender PA
    Bioorg Med Chem Lett; 2001 Mar; 11(5):719-22. PubMed ID: 11266177
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and tumor-promoting activities of 12-Epi-phorbol-12,13-dibutyrate.
    Irie K; Nakahara A; Ikawa Y; Tanaka M; Nakagawa Y; Nakamura Y; Ohigashi H; Wender PA
    Biosci Biotechnol Biochem; 2000 Nov; 64(11):2429-36. PubMed ID: 11193412
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and phorbol ester binding of the cysteine-rich domains of diacylglycerol kinase (DGK) isozymes. DGKgamma and DGKbeta are new targets of tumor-promoting phorbol esters.
    Shindo M; Irie K; Masuda A; Ohigashi H; Shirai Y; Miyasaka K; Saito N
    J Biol Chem; 2003 May; 278(20):18448-54. PubMed ID: 12621060
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ligand structure-activity requirements and phospholipid dependence for the binding of phorbol esters to protein kinase D.
    Wang QJ; Fang TW; Yang D; Lewin NE; Van Lint J; Marquez VE; Blumberg PM
    Mol Pharmacol; 2003 Dec; 64(6):1342-8. PubMed ID: 14645664
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential selectivity of ligands for the C1a and C1b phorbol ester binding domains of protein kinase Cdelta: possible correlation with tumor-promoting activity.
    Bögi K; Lorenzo PS; Szállási Z; Acs P; Wagner GS; Blumberg PM
    Cancer Res; 1998 Apr; 58(7):1423-8. PubMed ID: 9537243
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of chemical characteristics of the first and the second cysteine-rich domains of protein kinase C gamma.
    Irie K; Yanai Y; Oie K; Ishizawa J; Nakagawa Y; Ohigashi H; Wender PA; Kikkawa U
    Bioorg Med Chem; 1997 Aug; 5(8):1725-37. PubMed ID: 9313873
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective binding of phorbol esters and diacylglycerol by individual C1 domains of the PKD family.
    Chen J; Deng F; Li J; Wang QJ
    Biochem J; 2008 Apr; 411(2):333-42. PubMed ID: 18076381
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of diacyltetrol lipids as activators for the C1 domain of protein kinase C.
    Mamidi N; Gorai S; Mukherjee R; Manna D
    Mol Biosyst; 2012 Apr; 8(4):1275-85. PubMed ID: 22301880
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of hydrophobic residues in the C1b domain of protein kinase C delta on ligand and phospholipid interactions.
    Wang QJ; Fang TW; Nacro K; Marquez VE; Wang S; Blumberg PM
    J Biol Chem; 2001 Jun; 276(22):19580-7. PubMed ID: 11278612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.
    Choi SH; Czifra G; Kedei N; Lewin NE; Lazar J; Pu Y; Marquez VE; Blumberg PM
    J Biol Chem; 2008 Apr; 283(16):10543-9. PubMed ID: 18263588
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis of binding of high-affinity ligands to protein kinase C: prediction of the binding modes through a new molecular dynamics method and evaluation by site-directed mutagenesis.
    Pak Y; Enyedy IJ; Varady J; Kung JW; Lorenzo PS; Blumberg PM; Wang S
    J Med Chem; 2001 May; 44(11):1690-701. PubMed ID: 11356104
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Toward the identification of selective modulators of protein kinase C (PKC) isozymes: establishment of a binding assay for PKC isozymes using synthetic C1 peptide receptors and identification of the critical residues involved in the phorbol ester binding.
    Shindo M; Irie K; Nakahara A; Ohigashi H; Konishi H; Kikkawa U; Fukuda H; Wender PA
    Bioorg Med Chem; 2001 Aug; 9(8):2073-81. PubMed ID: 11504643
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis of RasGRP binding to high-affinity PKC ligands.
    Rong SB; Enyedy IJ; Qiao L; Zhao L; Ma D; Pearce LL; Lorenzo PS; Stone JC; Blumberg PM; Wang S; Kozikowski AP
    J Med Chem; 2002 Feb; 45(4):853-60. PubMed ID: 11831896
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specific binding of phorbol ester tumor promoters to mouse tissues and cultured cells.
    Blumberg PM; Delclos KB; Dunphy WG; Jaken S
    Carcinog Compr Surv; 1982; 7():519-35. PubMed ID: 7039833
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increases in acetylcholine release produced by phorbol esters are not mediated by protein kinase C at motor nerve endings.
    Searl TJ; Silinsky EM
    J Pharmacol Exp Ther; 1998 Apr; 285(1):247-51. PubMed ID: 9536018
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phorbol esters modulate the Ras exchange factor RasGRP3.
    Lorenzo PS; Kung JW; Bottorff DA; Garfield SH; Stone JC; Blumberg PM
    Cancer Res; 2001 Feb; 61(3):943-9. PubMed ID: 11221888
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The amide hydrogen of (-)-indolactam-V and benzolactam-V8's plays a critical role in protein kinase C binding and tumor-promoting activities.
    Nakagawa Y; Irie K; Nakamura Y; Ohigashi H
    Bioorg Med Chem Lett; 2001 Mar; 11(5):723-8. PubMed ID: 11266178
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the differential roles of the twin C1a and C1b domains of protein kinase C-delta.
    Pu Y; Garfield SH; Kedei N; Blumberg PM
    J Biol Chem; 2009 Jan; 284(2):1302-12. PubMed ID: 19001377
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Diacylglycerol kinase gamma is one of the specific receptors of tumor-promoting phorbol esters.
    Shindo M; Irie K; Ohigashi H; Kuriyama M; Saito N
    Biochem Biophys Res Commun; 2001 Nov; 289(2):451-6. PubMed ID: 11716494
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alkyl cinnamates as regulator for the C1 domain of protein kinase C isoforms.
    Mamidi N; Gorai S; Sahoo J; Manna D
    Chem Phys Lipids; 2012 Apr; 165(3):320-30. PubMed ID: 22414757
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.