263 related articles for article (PubMed ID: 11266469)
1. Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing.
Soriano S; Kang DE; Fu M; Pestell R; Chevallier N; Zheng H; Koo EH
J Cell Biol; 2001 Feb; 152(4):785-94. PubMed ID: 11266469
[TBL] [Abstract][Full Text] [Related]
2. Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis.
Xia X; Qian S; Soriano S; Wu Y; Fletcher AM; Wang XJ; Koo EH; Wu X; Zheng H
Proc Natl Acad Sci U S A; 2001 Sep; 98(19):10863-8. PubMed ID: 11517342
[TBL] [Abstract][Full Text] [Related]
3. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.
Steiner H; Capell A; Leimer U; Haass C
Eur Arch Psychiatry Clin Neurosci; 1999; 249(6):266-70. PubMed ID: 10653281
[TBL] [Abstract][Full Text] [Related]
4. Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling.
Berezovska O; Jack C; McLean P; Aster JC; Hicks C; Xia W; Wolfe MS; Kimberly WT; Weinmaster G; Selkoe DJ; Hyman BT
J Neurochem; 2000 Aug; 75(2):583-93. PubMed ID: 10899933
[TBL] [Abstract][Full Text] [Related]
5. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
De Strooper B; Annaert W; Cupers P; Saftig P; Craessaerts K; Mumm JS; Schroeter EH; Schrijvers V; Wolfe MS; Ray WJ; Goate A; Kopan R
Nature; 1999 Apr; 398(6727):518-22. PubMed ID: 10206645
[TBL] [Abstract][Full Text] [Related]
6. Effect of PS1 deficiency and an APP gamma-secretase inhibitor on Notch1 signaling in primary mammalian neurons.
Jack C; Berezovska O; Wolfe MS; Hyman BT
Brain Res Mol Brain Res; 2001 Mar; 87(2):166-74. PubMed ID: 11245918
[TBL] [Abstract][Full Text] [Related]
7. Notch1 competes with the amyloid precursor protein for gamma-secretase and down-regulates presenilin-1 gene expression.
LleĆ³ A; Berezovska O; Ramdya P; Fukumoto H; Raju S; Shah T; Hyman BT
J Biol Chem; 2003 Nov; 278(48):47370-5. PubMed ID: 12960155
[TBL] [Abstract][Full Text] [Related]
8. Requirement for presenilin 1 in facilitating lagged 2-mediated endoproteolysis and signaling of notch 1.
Martys-Zage JL; Kim SH; Berechid B; Bingham SJ; Chu S; Sklar J; Nye J; Sisodia SS
J Mol Neurosci; 2000 Dec; 15(3):189-204. PubMed ID: 11303783
[TBL] [Abstract][Full Text] [Related]
9. Role of presenilin in gamma-secretase cleavage of amyloid precursor protein.
Xia W
Exp Gerontol; 2000 Jul; 35(4):453-60. PubMed ID: 10959033
[TBL] [Abstract][Full Text] [Related]
10. Rapid Notch1 nuclear translocation after ligand binding depends on presenilin-associated gamma-secretase activity.
Berezovska O; Jack C; McLean P; Aster JC; Hicks C; Xia W; Wolfe MS; Weinmaster G; Selkoe DJ; Hyman BT
Ann N Y Acad Sci; 2000; 920():223-6. PubMed ID: 11193154
[TBL] [Abstract][Full Text] [Related]
11. Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis.
Kang DE; Soriano S; Xia X; Eberhart CG; De Strooper B; Zheng H; Koo EH
Cell; 2002 Sep; 110(6):751-62. PubMed ID: 12297048
[TBL] [Abstract][Full Text] [Related]
12. Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of beta-catenin phosphorylation.
Kawamura Y; Kikuchi A; Takada R; Takada S; Sudoh S; Shibamoto S; Yanagisawa K; Komano H
Eur J Biochem; 2001 May; 268(10):3036-41. PubMed ID: 11358522
[TBL] [Abstract][Full Text] [Related]
13. Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.
Li G; Percontino L; Sun Q; Qazi AS; Frederikse PH
Mol Vis; 2003 May; 9():179-83. PubMed ID: 12740567
[TBL] [Abstract][Full Text] [Related]
14. Presenilin interactions and Alzheimer's disease.
Kosik KS
Science; 1998 Jan; 279(5350):463-5. PubMed ID: 9454341
[No Abstract] [Full Text] [Related]
15. Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals.
Li T; Ma G; Cai H; Price DL; Wong PC
J Neurosci; 2003 Apr; 23(8):3272-7. PubMed ID: 12716934
[TBL] [Abstract][Full Text] [Related]
16. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein.
De Strooper B; Saftig P; Craessaerts K; Vanderstichele H; Guhde G; Annaert W; Von Figura K; Van Leuven F
Nature; 1998 Jan; 391(6665):387-90. PubMed ID: 9450754
[TBL] [Abstract][Full Text] [Related]
17. Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells.
Palacino JJ; Berechid BE; Alexander P; Eckman C; Younkin S; Nye JS; Wolozin B
J Biol Chem; 2000 Jan; 275(1):215-22. PubMed ID: 10617607
[TBL] [Abstract][Full Text] [Related]
18. Partial loss of presenilins causes seborrheic keratosis and autoimmune disease in mice.
Tournoy J; Bossuyt X; Snellinx A; Regent M; Garmyn M; Serneels L; Saftig P; Craessaerts K; De Strooper B; Hartmann D
Hum Mol Genet; 2004 Jul; 13(13):1321-31. PubMed ID: 15128703
[TBL] [Abstract][Full Text] [Related]
19. Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling.
Kirschenbaum F; Hsu SC; Cordell B; McCarthy JV
J Biol Chem; 2001 Mar; 276(10):7366-75. PubMed ID: 11104755
[TBL] [Abstract][Full Text] [Related]
20. Presenilin-1 deficiency leads to loss of Cajal-Retzius neurons and cortical dysplasia similar to human type 2 lissencephaly.
Hartmann D; De Strooper B; Saftig P
Curr Biol; 1999 Jul; 9(14):719-27. PubMed ID: 10421573
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]