BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 11272313)

  • 1. Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen.
    Sidelmann UG; Bjørnsdottir I; Shockcor JP; Hansen SH; Lindon JC; Nicholson JK
    J Pharm Biomed Anal; 2001 Feb; 24(4):569-79. PubMed ID: 11272313
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HPLC/1H NMR spectroscopic studies of the reactive alpha-1-O-acyl isomer formed during acyl migration of S-naproxen beta-1-O-acyl glucuronide.
    Corcoran O; Mortensen RW; Hansen SH; Troke J; Nicholson JK
    Chem Res Toxicol; 2001 Oct; 14(10):1363-70. PubMed ID: 11599927
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combined HPLC, NMR spectroscopy, and ion-trap mass spectrometry with application to the detection and characterization of xenobiotic and endogenous metabolites in human urine.
    Shockcor JP; Unger SE; Wilson ID; Foxall PJ; Nicholson JK; Lindon JC
    Anal Chem; 1996 Dec; 68(24):4431-5. PubMed ID: 8972626
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LC-1H NMR used for determination of the elution order of S-naproxen glucuronide isomers in two isocratic reversed-phase LC-systems.
    Mortensen RW; Corcoran O; Cornett C; Sidelmann UG; Troke J; Lindon JC; Nicholson JK; Hansen SH
    J Pharm Biomed Anal; 2001 Jan; 24(3):477-85. PubMed ID: 11199227
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of metabolites in human hepatic bile using 800 MHz 1H NMR spectroscopy, HPLC-NMR/MS and UPLC-MS.
    Duarte IF; Legido-Quigley C; Parker DA; Swann JR; Spraul M; Braumann U; Gil AM; Holmes E; Nicholson JK; Murphy GM; Vilca-Melendez H; Heaton N; Lindon JC
    Mol Biosyst; 2009 Feb; 5(2):180-90. PubMed ID: 19156264
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HPLC-NMR with severe column overloading: fast-track metabolite identification in urine and bile samples from rat and dog treated with [14C]-ZD6126.
    Lenz EM; D'Souza RA; Jordan AC; King CD; Smith SM; Phillips PJ; McCormick AD; Roberts DW
    J Pharm Biomed Anal; 2007 Feb; 43(3):1065-77. PubMed ID: 17030109
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Isolation and identification of human metabolites from a novel anti-tumor candidate drug 5-chlorogenic acid injection by HPLC-HRMS/MS
    Ren T; Wang Y; Wang C; Zhang M; Huang W; Jiang J; Li W; Zhang J
    Anal Bioanal Chem; 2017 Dec; 409(30):7035-7048. PubMed ID: 29116355
    [TBL] [Abstract][Full Text] [Related]  

  • 8. S-naproxen-beta-1-O-acyl glucuronide degradation kinetic studies by stopped-flow high-performance liquid chromatography-1H NMR and high-performance liquid chromatography-UV.
    Mortensen RW; Corcoran O; Cornett C; Sidelmann UG; Lindon JC; Nicholson JK; Hansen SH
    Drug Metab Dispos; 2001 Apr; 29(4 Pt 1):375-80. PubMed ID: 11259319
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development.
    Lindon JC; Nicholson JK; Wilson ID
    J Chromatogr B Biomed Sci Appl; 2000 Oct; 748(1):233-58. PubMed ID: 11092602
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Purification and 1H NMR spectroscopic characterization of phase II metabolites of tolfenamic acid.
    Sidelmann UG; Christiansen E; Krogh L; Cornett C; Tjørnelund J; Hansen SH
    Drug Metab Dispos; 1997 Jun; 25(6):725-31. PubMed ID: 9193874
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of liquid chromatography coupled with high-field 1H NMR spectroscopy for drug metabolite detection and characterization: the identification of paracetamol metabolites in urine and bile.
    Spraul M; Hofmann M; Lindon JC; Farrant RD; Seddon MJ; Nicholson JK; Wilson ID
    NMR Biomed; 1994 Nov; 7(7):295-303. PubMed ID: 7718429
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization and quantification of metabolites of racemic ketoprofen excreted in urine following oral administration to man by 1H-NMR spectroscopy, directly coupled HPLC-MS and HPLC-NMR, and circular dichroism.
    Skordi E; Wilson ID; Lindon JC; Nicholson JK
    Xenobiotica; 2004; 34(11-12):1075-89. PubMed ID: 15801549
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mass spectrometrically detected directly coupled high performance liquid chromatography/nuclear magnetic resonance spectroscopy/mass spectrometry for the identification of xenobiotic metabolites in maize plants.
    Bailey NJ; Stanley PD; Hadfield ST; Lindon JC; Nicholson JK
    Rapid Commun Mass Spectrom; 2000; 14(8):679-84. PubMed ID: 10786907
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Direct characterization of drug glucuronide isomers in human urine by HPLC-NMR spectroscopy: application to the positional isomers of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid glucuronide.
    Lenz EM; Greatbanks D; Wilson ID; Spraul M; Hofmann M; Troke J; Lindon JC; Nicholson JK
    Anal Chem; 1996 Sep; 68(17):2832-7. PubMed ID: 8794920
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of phenacetin metabolites in human urine after administration of phenacetin-C2H3: measurement of futile metabolic deacetylation via HPLC/MS-SPE-NMR and HPLC-ToF MS.
    Nicholls AW; Wilson ID; Godejohann M; Nicholson JK; Shockcor JP
    Xenobiotica; 2006 Jul; 36(7):615-29. PubMed ID: 16864507
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Coupling of HPLC with 19F- and 1H-NMR spectroscopy to investigate the human urinary excretion of flurbiprofen metabolites.
    Spraul M; Hofmann M; Wilson ID; Lenz E; Nicholson JK; Lindon JC
    J Pharm Biomed Anal; 1993 Oct; 11(10):1009-15. PubMed ID: 8305581
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mass directed peak selection, an efficient method of drug metabolite identification using directly coupled liquid chromatography-mass spectrometry-nuclear magnetic resonance spectroscopy.
    Dear GJ; Plumb RS; Sweatman BC; Ayrton J; Lindon JC; Nicholson JK; Ismail IM
    J Chromatogr B Biomed Sci Appl; 2000 Oct; 748(1):281-93. PubMed ID: 11092605
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Quantitative studies on the urinary metabolic fate of 2-chloro-4-trifluoromethylaniline in the rat using 19F-NMR spectroscopy and directly coupled HPLC-NMR-MS.
    Scarfe GB; Wright B; Clayton E; Taylor S; Wilson ID; Lindon JC; Nicholson JK
    Xenobiotica; 1999 Jan; 29(1):77-91. PubMed ID: 10078841
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Investigation of the feasibility of directly-coupled HPLC-NMR with 2H detection with application to the metabolism of N-dimethylformamide-d7.
    Farrant RD; Cupid BC; Nicholson JK; Lindon JC
    J Pharm Biomed Anal; 1997 Sep; 16(1):1-5. PubMed ID: 9447545
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 10.