BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 11274964)

  • 1. Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIalpha expression.
    Salmena L; Lam V; McPherson JP; Goldenberg GJ
    Biochem Pharmacol; 2001 Apr; 61(7):795-802. PubMed ID: 11274964
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs.
    Ogiso Y; Tomida A; Lei S; Omura S; Tsuruo T
    Cancer Res; 2000 May; 60(9):2429-34. PubMed ID: 10811120
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glucose-regulated stresses cause degradation of DNA topoisomerase IIalpha by inducing nuclear proteasome during G1 cell cycle arrest in cancer cells.
    Kim HD; Tomida A; Ogiso Y; Tsuruo T
    J Cell Physiol; 1999 Jul; 180(1):97-104. PubMed ID: 10362022
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Degradation of topoisomerase IIalpha during adenovirus E1A-induced apoptosis is mediated by the activation of the ubiquitin proteolysis system.
    Nakajima T; Morita K; Ohi N; Arai T; Nozaki N; Kikuchi A; Osaka F; Yamao F; Oda K
    J Biol Chem; 1996 Oct; 271(40):24842-9. PubMed ID: 8798759
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered drug interaction and regulation of topoisomerase IIbeta: potential mechanisms governing sensitivity of HL-60 cells to amsacrine and etoposide.
    Grabowski DR; Holmes KA; Aoyama M; Ye Y; Rybicki LA; Bukowski RM; Ganapathi MK; Hickson ID; Ganapathi R
    Mol Pharmacol; 1999 Dec; 56(6):1340-5. PubMed ID: 10570063
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA Topoisomerase IIα contributes to the early steps of adipogenesis in 3T3-L1 cells.
    Jacobsen RG; Mazloumi Gavgani F; Mellgren G; Lewis AE
    Cell Signal; 2016 Oct; 28(10):1593-603. PubMed ID: 27404349
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhanced etoposide sensitivity following adenovirus-mediated human topoisomerase IIalpha gene transfer is independent of topoisomerase IIbeta.
    Zhou Z; Zwelling LA; Ganapathi R; Kleinerman ES
    Br J Cancer; 2001 Sep; 85(5):747-51. PubMed ID: 11531262
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differences in the longevity of topo IIalpha and topo IIbeta drug-stabilized cleavable complexes and the relationship to drug sensitivity.
    Errington F; Willmore E; Leontiou C; Tilby MJ; Austin CA
    Cancer Chemother Pharmacol; 2004 Feb; 53(2):155-62. PubMed ID: 14504921
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The SUMO pathway is required for selective degradation of DNA topoisomerase IIbeta induced by a catalytic inhibitor ICRF-193(1).
    Isik S; Sano K; Tsutsui K; Seki M; Enomoto T; Saitoh H; Tsutsui K
    FEBS Lett; 2003 Jul; 546(2-3):374-8. PubMed ID: 12832072
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Carbamate analogues of amsacrine active against non-cycling cells: relative activity against topoisomerases IIalpha and beta.
    Turnbull RM; Meczes EL; Perenna Rogers M; Lock RB; Sullivan DM; Finlay GJ; Baguley BC; Austin CA
    Cancer Chemother Pharmacol; 1999; 44(4):275-82. PubMed ID: 10447574
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain.
    Qin Y; Meng L; Hu C; Duan W; Zuo Z; Lin L; Zhang X; Ding J
    Mol Cancer Ther; 2007 Sep; 6(9):2429-40. PubMed ID: 17876042
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Etoposide targets topoisomerase IIalpha and IIbeta in leukemic cells: isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique.
    Willmore E; Frank AJ; Padget K; Tilby MJ; Austin CA
    Mol Pharmacol; 1998 Jul; 54(1):78-85. PubMed ID: 9658192
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Influence of cell cycle and oncogene activity upon topoisomerase IIalpha expression and drug toxicity.
    Stacey DW; Hitomi M; Chen G
    Mol Cell Biol; 2000 Dec; 20(24):9127-37. PubMed ID: 11094065
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.
    Kozuki T; Chikamori K; Surleac MD; Micluta MA; Petrescu AJ; Norris EJ; Elson P; Hoeltge GA; Grabowski DR; Porter ACG; Ganapathi RN; Ganapathi MK
    Nucleic Acids Res; 2017 Jun; 45(10):5995-6010. PubMed ID: 28472494
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of topoisomerase IIalpha expression by transforming growth factor-beta1 is abrogated by the papillomavirus E7 protein.
    Satterwhite DJ; White RL; Matsunami N; Neufeld KL
    Cancer Res; 2000 Dec; 60(24):6989-94. PubMed ID: 11156401
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Murine transgenic cells lacking DNA topoisomerase IIbeta are resistant to acridines and mitoxantrone: analysis of cytotoxicity and cleavable complex formation.
    Errington F; Willmore E; Tilby MJ; Li L; Li G; Li W; Baguley BC; Austin CA
    Mol Pharmacol; 1999 Dec; 56(6):1309-16. PubMed ID: 10570059
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells.
    Huan JY; Streicher JM; Bleyle LA; Koop DR
    Toxicol Appl Pharmacol; 2004 Sep; 199(3):332-43. PubMed ID: 15364548
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Early degradation of paternal mitochondria in domestic pig (Sus scrofa) is prevented by selective proteasomal inhibitors lactacystin and MG132.
    Sutovsky P; McCauley TC; Sutovsky M; Day BN
    Biol Reprod; 2003 May; 68(5):1793-800. PubMed ID: 12606393
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidence for a critical role of DNA topoisomerase IIalpha in drug sensitivity revealed by inducible antisense RNA in a human leukaemia cell line.
    Towatari M; Adachi K; Marunouchi T; Saito H
    Br J Haematol; 1998 Jun; 101(3):548-51. PubMed ID: 9633900
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Salicylate, a catalytic inhibitor of topoisomerase II, inhibits DNA cleavage and is selective for the α isoform.
    Bau JT; Kang Z; Austin CA; Kurz EU
    Mol Pharmacol; 2014 Feb; 85(2):198-207. PubMed ID: 24220011
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.