These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 11278424)

  • 1. Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2.
    Choi EK; Zaidi NF; Miller JS; Crowley AC; Merriam DE; Lilliehook C; Buxbaum JD; Wasco W
    J Biol Chem; 2001 Jun; 276(22):19197-204. PubMed ID: 11278424
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment.
    Buxbaum JD; Choi EK; Luo Y; Lilliehook C; Crowley AC; Merriam DE; Wasco W
    Nat Med; 1998 Oct; 4(10):1177-81. PubMed ID: 9771752
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Subcellular localization of presenilin 2 endoproteolytic C-terminal fragments.
    Tekirian TL; Merriam DE; Marshansky V; Miller J; Crowley AC; Chan H; Ausiello D; Brown D; Buxbaum JD; Xia W; Wasco W
    Brain Res Mol Brain Res; 2001 Nov; 96(1-2):14-20. PubMed ID: 11731004
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart.
    Alves da Costa C; Mattson MP; Ancolio K; Checler F
    J Biol Chem; 2003 Apr; 278(14):12064-9. PubMed ID: 12556443
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Calsenilin reverses presenilin-mediated enhancement of calcium signaling.
    Leissring MA; Yamasaki TR; Wasco W; Buxbaum JD; Parker I; LaFerla FM
    Proc Natl Acad Sci U S A; 2000 Jul; 97(15):8590-3. PubMed ID: 10900016
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex.
    Capell A; Grünberg J; Pesold B; Diehlmann A; Citron M; Nixon R; Beyreuther K; Selkoe DJ; Haass C
    J Biol Chem; 1998 Feb; 273(6):3205-11. PubMed ID: 9452432
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pro-apoptotic function of calsenilin/DREAM/KChIP3.
    Jo DG; Kim MJ; Choi YH; Kim IK; Song YH; Woo HN; Chung CW; Jung YK
    FASEB J; 2001 Mar; 15(3):589-91. PubMed ID: 11259376
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease.
    Kim TW; Pettingell WH; Jung YK; Kovacs DM; Tanzi RE
    Science; 1997 Jul; 277(5324):373-6. PubMed ID: 9219695
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biochemical and immunocytochemical characterization of calsenilin in mouse brain.
    Zaidi NF; Berezovska O; Choi EK; Miller JS; Chan H; Lilliehook C; Hyman BT; Buxbaum JD; Wasco W
    Neuroscience; 2002; 114(1):247-63. PubMed ID: 12207970
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Contribution of presenilin/gamma-secretase to calsenilin-mediated apoptosis.
    Jo DG; Chang JW; Hong HS; Mook-Jung I; Jung YK
    Biochem Biophys Res Commun; 2003 May; 305(1):62-6. PubMed ID: 12732196
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of calsenilin at Ser63 regulates its cleavage by caspase-3.
    Choi EK; Miller JS; Zaidi NF; Salih E; Buxbaum JD; Wasco W
    Mol Cell Neurosci; 2003 Jul; 23(3):495-506. PubMed ID: 12837631
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of calsenilin in neurons and astrocytes in the Alzheimer's disease brain.
    Jin JK; Choi JK; Wasco W; Buxbaum JD; Kozlowski PB; Carp RI; Kim YS; Choi EK
    Neuroreport; 2005 Apr; 16(5):451-5. PubMed ID: 15770150
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Immunohistochemical analysis of presenilin 2 expression in the mouse brain: distribution pattern and co-localization with presenilin 1 protein.
    Blanchard V; Czech C; Bonici B; Clavel N; Gohin M; Dalet K; Revah F; Pradier L; Imperato A; Moussaoui S
    Brain Res; 1997 May; 758(1-2):209-17. PubMed ID: 9203550
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pro-apoptotic effect of presenilin 2 (PS2) overexpression is associated with down-regulation of Bcl-2 in cultured neurons.
    Araki W; Yuasa K; Takeda S; Takeda K; Shirotani K; Takahashi K; Tabira T
    J Neurochem; 2001 Dec; 79(6):1161-8. PubMed ID: 11752057
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence that intramolecular associations between presenilin domains are obligatory for endoproteolytic processing.
    Saura CA; Tomita T; Davenport F; Harris CL; Iwatsubo T; Thinakaran G
    J Biol Chem; 1999 May; 274(20):13818-23. PubMed ID: 10318786
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases.
    van de Craen M; de Jonghe C; van den Brande I; Declercq W; van Gassen G; van Criekinge W; Vanderhoeven I; Fiers W; van Broeckhoven C; Hendriks L; Vandenabeele P
    FEBS Lett; 1999 Feb; 445(1):149-54. PubMed ID: 10069390
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alzheimer's disease-associated presenilin 2 interacts with DRAL, an LIM-domain protein.
    Tanahashi H; Tabira T
    Hum Mol Genet; 2000 Sep; 9(15):2281-9. PubMed ID: 11001931
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation.
    Tesco G; Kim TW; Diehlmann A; Beyreuther K; Tanzi RE
    J Biol Chem; 1998 Dec; 273(51):33909-14. PubMed ID: 9852041
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein.
    Stabler SM; Ostrowski LL; Janicki SM; Monteiro MJ
    J Cell Biol; 1999 Jun; 145(6):1277-92. PubMed ID: 10366599
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The influence of endoproteolytic processing of familial Alzheimer's disease presenilin 2 on abeta42 amyloid peptide formation.
    Jacobsen H; Reinhardt D; Brockhaus M; Bur D; Kocyba C; Kurt H; Grim MG; Baumeister R; Loetscher H
    J Biol Chem; 1999 Dec; 274(49):35233-9. PubMed ID: 10575009
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.