BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

325 related articles for article (PubMed ID: 11278610)

  • 1. The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.
    Kamizono S; Hanada T; Yasukawa H; Minoguchi S; Kato R; Minoguchi M; Hattori K; Hatakeyama S; Yada M; Morita S; Kitamura T; Kato H; Nakayama Ki ; Yoshimura A
    J Biol Chem; 2001 Apr; 276(16):12530-8. PubMed ID: 11278610
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The TEL-Jak2 oncoprotein induces Socs1 expression and altered cytokine response in Ba/F3 cells.
    Monni R; Santos SC; Mauchauffe M; Berger R; Ghysdael J; Gouilleux F; Gisselbrecht S; Bernard O; Penard-Lacronique V
    Oncogene; 2001 Feb; 20(7):849-58. PubMed ID: 11314018
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families.
    Kamura T; Sato S; Haque D; Liu L; Kaelin WG; Conaway RC; Conaway JW
    Genes Dev; 1998 Dec; 12(24):3872-81. PubMed ID: 9869640
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation.
    Zhang JG; Farley A; Nicholson SE; Willson TA; Zugaro LM; Simpson RJ; Moritz RL; Cary D; Richardson R; Hausmann G; Kile BT; Kent SB; Alexander WS; Metcalf D; Hilton DJ; Nicola NA; Baca M
    Proc Natl Acad Sci U S A; 1999 Mar; 96(5):2071-6. PubMed ID: 10051596
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells.
    Lacronique V; Boureux A; Monni R; Dumon S; Mauchauffé M; Mayeux P; Gouilleux F; Berger R; Gisselbrecht S; Ghysdael J; Bernard OA
    Blood; 2000 Mar; 95(6):2076-83. PubMed ID: 10706877
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation.
    Frantsve J; Schwaller J; Sternberg DW; Kutok J; Gilliland DG
    Mol Cell Biol; 2001 May; 21(10):3547-57. PubMed ID: 11313480
    [TBL] [Abstract][Full Text] [Related]  

  • 7. VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
    Kamura T; Maenaka K; Kotoshiba S; Matsumoto M; Kohda D; Conaway RC; Conaway JW; Nakayama KI
    Genes Dev; 2004 Dec; 18(24):3055-65. PubMed ID: 15601820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling.
    Narazaki M; Fujimoto M; Matsumoto T; Morita Y; Saito H; Kajita T; Yoshizaki K; Naka T; Kishimoto T
    Proc Natl Acad Sci U S A; 1998 Oct; 95(22):13130-4. PubMed ID: 9789053
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The tumor suppressor activity of SOCS-1.
    Rottapel R; Ilangumaran S; Neale C; La Rose J; Ho JM; Nguyen MH; Barber D; Dubreuil P; de Sepulveda P
    Oncogene; 2002 Jun; 21(28):4351-62. PubMed ID: 12080466
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase.
    Kamura T; Burian D; Yan Q; Schmidt SL; Lane WS; Querido E; Branton PE; Shilatifard A; Conaway RC; Conaway JW
    J Biol Chem; 2001 Aug; 276(32):29748-53. PubMed ID: 11384984
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.
    Bullock AN; Debreczeni JE; Edwards AM; Sundström M; Knapp S
    Proc Natl Acad Sci U S A; 2006 May; 103(20):7637-42. PubMed ID: 16675548
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box.
    Hanada T; Yoshida T; Kinjyo I; Minoguchi S; Yasukawa H; Kato S; Mimata H; Nomura Y; Seki Y; Kubo M; Yoshimura A
    J Biol Chem; 2001 Nov; 276(44):40746-54. PubMed ID: 11522790
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A three-dimensional model of Suppressor Of Cytokine Signalling 1 (SOCS-1).
    Giordanetto F; Kroemer RT
    Protein Eng; 2003 Feb; 16(2):115-24. PubMed ID: 12676980
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms.
    Ram PA; Waxman DJ
    J Biol Chem; 1999 Dec; 274(50):35553-61. PubMed ID: 10585430
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation.
    Iwamoto T; Senga T; Naito Y; Matsuda S; Miyake Y; Yoshimura A; Hamaguchi M
    Oncogene; 2000 Sep; 19(41):4795-801. PubMed ID: 11032030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fusion of the ets transcription factor TEL to Jak2 results in constitutive Jak-Stat signaling.
    Ho JM; Beattie BK; Squire JA; Frank DA; Barber DL
    Blood; 1999 Jun; 93(12):4354-64. PubMed ID: 10361134
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3'-kinase/protein kinase B signaling pathway.
    Nguyen MH; Ho JM; Beattie BK; Barber DL
    J Biol Chem; 2001 Aug; 276(35):32704-13. PubMed ID: 11435425
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
    Kamura T; Koepp DM; Conrad MN; Skowyra D; Moreland RJ; Iliopoulos O; Lane WS; Kaelin WG; Elledge SJ; Conaway RC; Harper JW; Conaway JW
    Science; 1999 Apr; 284(5414):657-61. PubMed ID: 10213691
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.
    Rui L; Yuan M; Frantz D; Shoelson S; White MF
    J Biol Chem; 2002 Nov; 277(44):42394-8. PubMed ID: 12228220
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.
    De Sepulveda P; Ilangumaran S; Rottapel R
    J Biol Chem; 2000 May; 275(19):14005-8. PubMed ID: 10747851
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.