BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 11278781)

  • 1. Analysis of the cyclic nucleotide binding domain of the HERG potassium channel and interactions with KCNE2.
    Cui J; Kagan A; Qin D; Mathew J; Melman YF; McDonald TV
    J Biol Chem; 2001 May; 276(20):17244-51. PubMed ID: 11278781
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification and functional characterization of a novel KCNE2 (MiRP1) mutation that alters HERG channel kinetics.
    Isbrandt D; Friederich P; Solth A; Haverkamp W; Ebneth A; Borggrefe M; Funke H; Sauter K; Breithardt G; Pongs O; Schulze-Bahr E
    J Mol Med (Berl); 2002 Aug; 80(8):524-32. PubMed ID: 12185453
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.
    Ficker E; Obejero-Paz CA; Zhao S; Brown AM
    J Biol Chem; 2002 Feb; 277(7):4989-98. PubMed ID: 11741928
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of a COOH-terminal segment involved in maturation and stability of human ether-a-go-go-related gene potassium channels.
    Akhavan A; Atanasiu R; Shrier A
    J Biol Chem; 2003 Oct; 278(41):40105-12. PubMed ID: 12885765
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deletion of protein kinase A phosphorylation sites in the HERG potassium channel inhibits activation shift by protein kinase A.
    Thomas D; Zhang W; Karle CA; Kathöfer S; Schöls W; Kübler W; Kiehn J
    J Biol Chem; 1999 Sep; 274(39):27457-62. PubMed ID: 10488078
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Defective human Ether-à-go-go-related gene trafficking linked to an endoplasmic reticulum retention signal in the C terminus.
    Kupershmidt S; Yang T; Chanthaphaychith S; Wang Z; Towbin JA; Roden DM
    J Biol Chem; 2002 Jul; 277(30):27442-8. PubMed ID: 12021266
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The dominant negative LQT2 mutation A561V reduces wild-type HERG expression.
    Kagan A; Yu Z; Fishman GI; McDonald TV
    J Biol Chem; 2000 Apr; 275(15):11241-8. PubMed ID: 10753933
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C.
    Delisle BP; Anderson CL; Balijepalli RC; Anson BD; Kamp TJ; January CT
    J Biol Chem; 2003 Sep; 278(37):35749-54. PubMed ID: 12837749
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel missense mutation in the cyclic nucleotide-binding domain of HERG causes long QT syndrome.
    Satler CA; Walsh EP; Vesely MR; Plummer MH; Ginsburg GS; Jacob HJ
    Am J Med Genet; 1996 Oct; 65(1):27-35. PubMed ID: 8914737
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclic AMP regulates the HERG K(+) channel by dual pathways.
    Cui J; Melman Y; Palma E; Fishman GI; McDonald TV
    Curr Biol; 2000 Jun; 10(11):671-4. PubMed ID: 10837251
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Long-QT syndrome-associated missense mutations in the pore helix of the HERG potassium channel.
    Huang FD; Chen J; Lin M; Keating MT; Sanguinetti MC
    Circulation; 2001 Aug; 104(9):1071-5. PubMed ID: 11524404
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency.
    Paulussen A; Raes A; Matthijs G; Snyders DJ; Cohen N; Aerssens J
    J Biol Chem; 2002 Dec; 277(50):48610-6. PubMed ID: 12354768
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-à-go-go-Related Gene.
    Roti EC; Myers CD; Ayers RA; Boatman DE; Delfosse SA; Chan EK; Ackerman MJ; January CT; Robertson GA
    J Biol Chem; 2002 Dec; 277(49):47779-85. PubMed ID: 12270925
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of S818L mutation in HERG C-terminus in LQT2. Modification of activation-deactivation gating properties.
    Nakajima T; Kurabayashi M; Ohyama Y; Kaneko Y; Furukawa T; Itoh T; Taniguchi Y; Tanaka T; Nakamura Y; Hiraoka M; Nagai R
    FEBS Lett; 2000 Sep; 481(2):197-203. PubMed ID: 10996323
    [TBL] [Abstract][Full Text] [Related]  

  • 15. KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel.
    Tinel N; Diochot S; Borsotto M; Lazdunski M; Barhanin J
    EMBO J; 2000 Dec; 19(23):6326-30. PubMed ID: 11101505
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels.
    Chen J; Seebohm G; Sanguinetti MC
    Proc Natl Acad Sci U S A; 2002 Sep; 99(19):12461-6. PubMed ID: 12209010
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Long QT syndrome-associated mutations in the Per-Arnt-Sim (PAS) domain of HERG potassium channels accelerate channel deactivation.
    Chen J; Zou A; Splawski I; Keating MT; Sanguinetti MC
    J Biol Chem; 1999 Apr; 274(15):10113-8. PubMed ID: 10187793
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Long QT syndrome: cellular basis and arrhythmia mechanism in LQT2.
    January CT; Gong Q; Zhou Z
    J Cardiovasc Electrophysiol; 2000 Dec; 11(12):1413-8. PubMed ID: 11196567
    [TBL] [Abstract][Full Text] [Related]  

  • 19. C-terminal HERG mutations: the role of hypokalemia and a KCNQ1-associated mutation in cardiac event occurrence.
    Berthet M; Denjoy I; Donger C; Demay L; Hammoude H; Klug D; Schulze-Bahr E; Richard P; Funke H; Schwartz K; Coumel P; Hainque B; Guicheney P
    Circulation; 1999 Mar; 99(11):1464-70. PubMed ID: 10086971
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity.
    Kagan A; Melman YF; Krumerman A; McDonald TV
    EMBO J; 2002 Apr; 21(8):1889-98. PubMed ID: 11953308
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.