BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

740 related articles for article (PubMed ID: 11278799)

  • 1. Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1.
    Slack DN; Seternes OM; Gabrielsen M; Keyse SM
    J Biol Chem; 2001 May; 276(19):16491-500. PubMed ID: 11278799
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation.
    Hutter D; Chen P; Barnes J; Liu Y
    Biochem J; 2000 Nov; 352 Pt 1(Pt 1):155-63. PubMed ID: 11062068
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and their ability to activate the phosphatase catalytically.
    Chen P; Hutter D; Yang X; Gorospe M; Davis RJ; Liu Y
    J Biol Chem; 2001 Aug; 276(31):29440-9. PubMed ID: 11387337
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The mitogen-activated protein kinase phosphatase-3 N-terminal noncatalytic region is responsible for tight substrate binding and enzymatic specificity.
    Muda M; Theodosiou A; Gillieron C; Smith A; Chabert C; Camps M; Boschert U; Rodrigues N; Davies K; Ashworth A; Arkinstall S
    J Biol Chem; 1998 Apr; 273(15):9323-9. PubMed ID: 9535927
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen-activated protein kinases.
    Muda M; Theodosiou A; Rodrigues N; Boschert U; Camps M; Gillieron C; Davies K; Ashworth A; Arkinstall S
    J Biol Chem; 1996 Nov; 271(44):27205-8. PubMed ID: 8910287
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells.
    Franklin CC; Kraft AS
    J Biol Chem; 1997 Jul; 272(27):16917-23. PubMed ID: 9202001
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Compartment-specific regulation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) mitogen-activated protein kinases (MAPKs) by ERK-dependent and non-ERK-dependent inductions of MAPK phosphatase (MKP)-3 and MKP-1 in differentiating P19 cells.
    Reffas S; Schlegel W
    Biochem J; 2000 Dec; 352 Pt 3(Pt 3):701-8. PubMed ID: 11104676
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase.
    Groom LA; Sneddon AA; Alessi DR; Dowd S; Keyse SM
    EMBO J; 1996 Jul; 15(14):3621-32. PubMed ID: 8670865
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase.
    Camps M; Nichols A; Gillieron C; Antonsson B; Muda M; Chabert C; Boschert U; Arkinstall S
    Science; 1998 May; 280(5367):1262-5. PubMed ID: 9596579
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation.
    Chu Y; Solski PA; Khosravi-Far R; Der CJ; Kelly K
    J Biol Chem; 1996 Mar; 271(11):6497-501. PubMed ID: 8626452
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Substrate recognition domains within extracellular signal-regulated kinase mediate binding and catalytic activation of mitogen-activated protein kinase phosphatase-3.
    Nichols A; Camps M; Gillieron C; Chabert C; Brunet A; Wilsbacher J; Cobb M; Pouyssegur J; Shaw JP; Arkinstall S
    J Biol Chem; 2000 Aug; 275(32):24613-21. PubMed ID: 10811804
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival.
    Wu W; Pew T; Zou M; Pang D; Conzen SD
    J Biol Chem; 2005 Feb; 280(6):4117-24. PubMed ID: 15590693
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MKP-7, a novel mitogen-activated protein kinase phosphatase, functions as a shuttle protein.
    Masuda K; Shima H; Watanabe M; Kikuchi K
    J Biol Chem; 2001 Oct; 276(42):39002-11. PubMed ID: 11489891
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The carboxyl-terminal domains of MKP-1 and MKP-2 have inhibitory effects on their phosphatase activity.
    Hutter D; Chen P; Li J; Barnes J; Liu Y
    Mol Cell Biochem; 2002 Apr; 233(1-2):107-17. PubMed ID: 12083364
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling.
    Lin YW; Yang JL
    J Biol Chem; 2006 Jan; 281(2):915-26. PubMed ID: 16286470
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular cloning and characterization of a novel dual specificity phosphatase, MKP-5.
    Tanoue T; Moriguchi T; Nishida E
    J Biol Chem; 1999 Jul; 274(28):19949-56. PubMed ID: 10391943
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of a murine gene encoding a developmentally regulated cytoplasmic dual-specificity mitogen-activated protein kinase phosphatase.
    Dickinson RJ; Williams DJ; Slack DN; Williamson J; Seternes OM; Keyse SM
    Biochem J; 2002 May; 364(Pt 1):145-55. PubMed ID: 11988087
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines.
    Matsuguchi T; Musikacharoen T; Johnson TR; Kraft AS; Yoshikai Y
    Mol Cell Biol; 2001 Oct; 21(20):6999-7009. PubMed ID: 11564882
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity.
    Bardwell AJ; Abdollahi M; Bardwell L
    Biochem J; 2003 Mar; 370(Pt 3):1077-85. PubMed ID: 12529172
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Both nuclear-cytoplasmic shuttling of the dual specificity phosphatase MKP-3 and its ability to anchor MAP kinase in the cytoplasm are mediated by a conserved nuclear export signal.
    Karlsson M; Mathers J; Dickinson RJ; Mandl M; Keyse SM
    J Biol Chem; 2004 Oct; 279(40):41882-91. PubMed ID: 15269220
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 37.