These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 11283003)

  • 1. Residues within the N-terminal domain of human topoisomerase I play a direct role in relaxation.
    Lisby M; Olesen JR; Skouboe C; Krogh BO; Straub T; Boege F; Velmurugan S; Martensen PM; Andersen AH; Jayaram M; Westergaard O; Knudsen BR
    J Biol Chem; 2001 Jun; 276(23):20220-7. PubMed ID: 11283003
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay.
    Stewart L; Ireton GC; Champoux JJ
    J Biol Chem; 1999 Nov; 274(46):32950-60. PubMed ID: 10551862
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thermotoga maritima-Escherichia coli chimeric topoisomerases. Answers about involvement of the carboxyl-terminal domain in DNA topoisomerase I-mediated catalysis.
    Viard T; Cossard R; Duguet M; de La Tour CB
    J Biol Chem; 2004 Jul; 279(29):30073-80. PubMed ID: 15140883
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disulfide cross-links reveal conserved features of DNA topoisomerase I architecture and a role for the N terminus in clamp closure.
    Palle K; Pattarello L; van der Merwe M; Losasso C; Benedetti P; Bjornsti MA
    J Biol Chem; 2008 Oct; 283(41):27767-27775. PubMed ID: 18693244
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function.
    Alsner J; Svejstrup JQ; Kjeldsen E; Sørensen BS; Westergaard O
    J Biol Chem; 1992 Jun; 267(18):12408-11. PubMed ID: 1319995
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding.
    Frøhlich RF; Andersen FF; Westergaard O; Andersen AH; Knudsen BR
    J Mol Biol; 2004 Feb; 336(1):93-103. PubMed ID: 14741206
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Indispensable, functionally complementing N and C-terminal domains constitute site-specific topoisomerase I.
    Jain P; Nagaraja V
    J Mol Biol; 2006 Apr; 357(5):1409-21. PubMed ID: 16490213
    [TBL] [Abstract][Full Text] [Related]  

  • 8. N-terminal region of the large subunit of Leishmania donovani bisubunit topoisomerase I is involved in DNA relaxation and interaction with the smaller subunit.
    Das BB; Sen N; Dasgupta SB; Ganguly A; Majumder HK
    J Biol Chem; 2005 Apr; 280(16):16335-44. PubMed ID: 15711017
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Locking the DNA topoisomerase I protein clamp inhibits DNA rotation and induces cell lethality.
    Woo MH; Losasso C; Guo H; Pattarello L; Benedetti P; Bjornsti MA
    Proc Natl Acad Sci U S A; 2003 Nov; 100(24):13767-72. PubMed ID: 14585933
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recombinogenic flap ligation mediated by human topoisomerase I.
    Andersen FF; Andersen KE; Kusk M; Frøhlich RF; Westergaard O; Andersen AH; Knudsen BR
    J Mol Biol; 2003 Jul; 330(2):235-46. PubMed ID: 12823964
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA contacts by protein domains of the molluscum contagiosum virus type-1B topoisomerase.
    Hwang Y; Park M; Fischer WH; Burgin A; Bushman F
    Virology; 1999 Sep; 262(2):479-91. PubMed ID: 10502526
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Resolution of Holliday junction substrates by human topoisomerase I.
    Hede MS; Petersen RL; Frøhlich RF; Krüger D; Andersen FF; Andersen AH; Knudsen BR
    J Mol Biol; 2007 Jan; 365(4):1076-92. PubMed ID: 17101150
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A model for the mechanism of human topoisomerase I.
    Stewart L; Redinbo MR; Qiu X; Hol WG; Champoux JJ
    Science; 1998 Mar; 279(5356):1534-41. PubMed ID: 9488652
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA topoisomerase I domain interactions impact enzyme activity and sensitivity to camptothecin.
    Wright CM; van der Merwe M; DeBrot AH; Bjornsti MA
    J Biol Chem; 2015 May; 290(19):12068-78. PubMed ID: 25795777
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impact of the C-terminal domain of topoisomerase IIalpha on the DNA cleavage activity of the human enzyme.
    Dickey JS; Osheroff N
    Biochemistry; 2005 Aug; 44(34):11546-54. PubMed ID: 16114891
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of DNA Binding by the Isolated N-Terminal Domain of Vaccinia Virus DNA Topoisomerase IB.
    Reed B; Yakovleva L; Shuman S; Ghose R
    Biochemistry; 2017 Jul; 56(26):3307-3317. PubMed ID: 28570045
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Residues 190-210 of human topoisomerase I are required for enzyme activity in vivo but not in vitro.
    Christensen MO; Barthelmes HU; Boege F; Mielke C
    Nucleic Acids Res; 2003 Dec; 31(24):7255-63. PubMed ID: 14654701
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of zinc removal on the conformation of Escherichia coli DNA topoisomerase I.
    Samuel M; Zhu CX; Villanueva GB; Tse-Dinh YC
    Arch Biochem Biophys; 1993 Jan; 300(1):302-8. PubMed ID: 8380965
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei.
    Liu LF; Miller KG
    Proc Natl Acad Sci U S A; 1981 Jun; 78(6):3487-91. PubMed ID: 6267594
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical characterization of the topoisomerase domain of Methanopyrus kandleri topoisomerase V.
    Rajan R; Osterman AK; Gast AT; Mondragón A
    J Biol Chem; 2014 Oct; 289(42):28898-909. PubMed ID: 25135643
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.