189 related articles for article (PubMed ID: 11283011)
21. ELISA analysis of beta-secretase cleavage of the Swedish amyloid precursor protein in the secretory and endocytic pathways.
Steinhilb ML; Turner RS; Gaut JR
J Neurochem; 2002 Mar; 80(6):1019-28. PubMed ID: 11953452
[TBL] [Abstract][Full Text] [Related]
22. Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells.
Chen F; Yang DS; Petanceska S; Yang A; Tandon A; Yu G; Rozmahel R; Ghiso J; Nishimura M; Zhang DM; Kawarai T; Levesque G; Mills J; Levesque L; Song YQ; Rogaeva E; Westaway D; Mount H; Gandy S; St George-Hyslop P; Fraser PE
J Biol Chem; 2000 Nov; 275(47):36794-802. PubMed ID: 10962005
[TBL] [Abstract][Full Text] [Related]
23. Retention of the Alzheimer's amyloid precursor fragment C99 in the endoplasmic reticulum prevents formation of amyloid beta-peptide.
Maltese WA; Wilson S; Tan Y; Suomensaari S; Sinha S; Barbour R; McConlogue L
J Biol Chem; 2001 Jun; 276(23):20267-79. PubMed ID: 11278337
[TBL] [Abstract][Full Text] [Related]
24. Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios.
Walker ES; Martinez M; Brunkan AL; Goate A
J Neurochem; 2005 Jan; 92(2):294-301. PubMed ID: 15663477
[TBL] [Abstract][Full Text] [Related]
25. Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein.
Weidemann A; Paliga K; Dürrwang U; Czech C; Evin G; Masters CL; Beyreuther K
Nat Med; 1997 Mar; 3(3):328-32. PubMed ID: 9055862
[TBL] [Abstract][Full Text] [Related]
26. Mutant presenilin 2 transgenic mouse: effect on an age-dependent increase of amyloid beta-protein 42 in the brain.
Oyama F; Sawamura N; Kobayashi K; Morishima-Kawashima M; Kuramochi T; Ito M; Tomita T; Maruyama K; Saido TC; Iwatsubo T; Capell A; Walter J; Grünberg J; Ueyama Y; Haass C; Ihara Y
J Neurochem; 1998 Jul; 71(1):313-22. PubMed ID: 9648880
[TBL] [Abstract][Full Text] [Related]
27. Mapping the APP/presenilin (PS) binding domains: the hydrophilic N-terminus of PS2 is sufficient for interaction with APP and can displace APP/PS1 interaction.
Pradier L; Carpentier N; Delalonde L; Clavel N; Bock MD; Buée L; Mercken L; Tocqué B; Czech C
Neurobiol Dis; 1999 Feb; 6(1):43-55. PubMed ID: 10078972
[TBL] [Abstract][Full Text] [Related]
28. Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease.
Xia W; Zhang J; Perez R; Koo EH; Selkoe DJ
Proc Natl Acad Sci U S A; 1997 Jul; 94(15):8208-13. PubMed ID: 9223340
[TBL] [Abstract][Full Text] [Related]
29. Presenilin-1-mediated retention of APP derivatives in early biosynthetic compartments.
Réchards M; Xia W; Oorschot V; van Dijk S; Annaert W; Selkoe DJ; Klumperman J
Traffic; 2006 Mar; 7(3):354-64. PubMed ID: 16497228
[TBL] [Abstract][Full Text] [Related]
30. The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.
Saura CA; Tomita T; Soriano S; Takahashi M; Leem JY; Honda T; Koo EH; Iwatsubo T; Thinakaran G
J Biol Chem; 2000 Jun; 275(22):17136-42. PubMed ID: 10748144
[TBL] [Abstract][Full Text] [Related]
31. Presenilin 1 mutations linked to familial Alzheimer's disease increase the intracellular levels of amyloid beta-protein 1-42 and its N-terminally truncated variant(s) which are generated at distinct sites.
Sudoh S; Kawamura Y; Sato S; Wang R; Saido TC; Oyama F; Sakaki Y; Komano H; Yanagisawa K
J Neurochem; 1998 Oct; 71(4):1535-43. PubMed ID: 9751187
[TBL] [Abstract][Full Text] [Related]
32. Distinct mechanisms by mutant presenilin 1 and 2 leading to increased intracellular levels of amyloid beta-protein 42 in Chinese hamster ovary cells.
Qi Y; Morishima-Kawashima M; Sato T; Mitsumori R; Ihara Y
Biochemistry; 2003 Feb; 42(4):1042-52. PubMed ID: 12549925
[TBL] [Abstract][Full Text] [Related]
33. Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides.
Greenfield JP; Tsai J; Gouras GK; Hai B; Thinakaran G; Checler F; Sisodia SS; Greengard P; Xu H
Proc Natl Acad Sci U S A; 1999 Jan; 96(2):742-7. PubMed ID: 9892704
[TBL] [Abstract][Full Text] [Related]
34. C terminus of presenilin is required for overproduction of amyloidogenic Abeta42 through stabilization and endoproteolysis of presenilin.
Tomita T; Takikawa R; Koyama A; Morohashi Y; Takasugi N; Saido TC; Maruyama K; Iwatsubo T
J Neurosci; 1999 Dec; 19(24):10627-34. PubMed ID: 10594046
[TBL] [Abstract][Full Text] [Related]
35. The production ratios of AICDε51 and Aβ42 by intramembrane proteolysis of βAPP do not always change in parallel.
Mori K; Okochi M; Tagami S; Nakayama T; Yanagida K; Kodama TS; Tatsumi S; Fujii K; Tanimukai H; Hashimoto R; Morihara T; Tanaka T; Kudo T; Funamoto S; Ihara Y; Takeda M
Psychogeriatrics; 2010 Sep; 10(3):117-23. PubMed ID: 20860566
[TBL] [Abstract][Full Text] [Related]
36. NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.
Buggia-Prevot V; Sevalle J; Rossner S; Checler F
J Biol Chem; 2008 Apr; 283(15):10037-47. PubMed ID: 18263584
[TBL] [Abstract][Full Text] [Related]
37. Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein.
Cai D; Leem JY; Greenfield JP; Wang P; Kim BS; Wang R; Lopes KO; Kim SH; Zheng H; Greengard P; Sisodia SS; Thinakaran G; Xu H
J Biol Chem; 2003 Jan; 278(5):3446-54. PubMed ID: 12435726
[TBL] [Abstract][Full Text] [Related]
38. Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production.
Moehlmann T; Winkler E; Xia X; Edbauer D; Murrell J; Capell A; Kaether C; Zheng H; Ghetti B; Haass C; Steiner H
Proc Natl Acad Sci U S A; 2002 Jun; 99(12):8025-30. PubMed ID: 12048239
[TBL] [Abstract][Full Text] [Related]
39. Alzheimer's disease-linked mutation of presenilin 2 (N141I-PS2) drastically lowers APPalpha secretion: control by the proteasome.
Marambaud P; Alves da Costa C; Ancolio K; Checler F
Biochem Biophys Res Commun; 1998 Nov; 252(1):134-8. PubMed ID: 9813158
[TBL] [Abstract][Full Text] [Related]
40. Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation.
Xia W; Ray WJ; Ostaszewski BL; Rahmati T; Kimberly WT; Wolfe MS; Zhang J; Goate AM; Selkoe DJ
Proc Natl Acad Sci U S A; 2000 Aug; 97(16):9299-304. PubMed ID: 10922078
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
