302 related articles for article (PubMed ID: 11285224)
1. Mechanism for down-regulation of CD28 by Nef.
Swigut T; Shohdy N; Skowronski J
EMBO J; 2001 Apr; 20(7):1593-604. PubMed ID: 11285224
[TBL] [Abstract][Full Text] [Related]
2. Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation.
Greenberg ME; Bronson S; Lock M; Neumann M; Pavlakis GN; Skowronski J
EMBO J; 1997 Dec; 16(23):6964-76. PubMed ID: 9384576
[TBL] [Abstract][Full Text] [Related]
3. Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis.
Lock M; Greenberg ME; Iafrate AJ; Swigut T; Muench J; Kirchhoff F; Shohdy N; Skowronski J
EMBO J; 1999 May; 18(10):2722-33. PubMed ID: 10329619
[TBL] [Abstract][Full Text] [Related]
4. Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression.
Swigut T; Iafrate AJ; Muench J; Kirchhoff F; Skowronski J
J Virol; 2000 Jun; 74(12):5691-701. PubMed ID: 10823877
[TBL] [Abstract][Full Text] [Related]
5. The conserved process of TCR/CD3 complex down-modulation by SIV Nef is mediated by the central core, not endocytic motifs.
Schaefer TM; Bell I; Pfeifer ME; Ghosh M; Trible RP; Fuller CL; Ashman C; Reinhart TA
Virology; 2002 Oct; 302(1):106-22. PubMed ID: 12429520
[TBL] [Abstract][Full Text] [Related]
6. Cooperative interactions of simian immunodeficiency virus Nef, AP-2, and CD3-zeta mediate the selective induction of T-cell receptor-CD3 endocytosis.
Swigut T; Greenberg M; Skowronski J
J Virol; 2003 Jul; 77(14):8116-26. PubMed ID: 12829850
[TBL] [Abstract][Full Text] [Related]
7. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes.
Greenberg ME; Iafrate AJ; Skowronski J
EMBO J; 1998 May; 17(10):2777-89. PubMed ID: 9582271
[TBL] [Abstract][Full Text] [Related]
8. Down-modulation of the costimulatory molecule, CD28, is a conserved activity of multiple SIV Nefs and is dependent on histidine 196 of Nef.
Bell I; Schaefer TM; Trible RP; Amedee A; Reinhart TA
Virology; 2001 Apr; 283(1):148-58. PubMed ID: 11312671
[TBL] [Abstract][Full Text] [Related]
9. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor.
Bresnahan PA; Yonemoto W; Ferrell S; Williams-Herman D; Geleziunas R; Greene WC
Curr Biol; 1998 Nov; 8(22):1235-8. PubMed ID: 9811606
[TBL] [Abstract][Full Text] [Related]
10. Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors.
Kirchhoff F; Schindler M; Bailer N; Renkema GH; Saksela K; Knoop V; Müller-Trutwin MC; Santiago ML; Bibollet-Ruche F; Dittmar MT; Heeney JL; Hahn BH; Münch J
J Virol; 2004 Jul; 78(13):6864-74. PubMed ID: 15194762
[TBL] [Abstract][Full Text] [Related]
11. Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling.
Iafrate AJ; Bronson S; Skowronski J
EMBO J; 1997 Feb; 16(4):673-84. PubMed ID: 9049297
[TBL] [Abstract][Full Text] [Related]
12. Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4.
Bresnahan PA; Yonemoto W; Greene WC
J Immunol; 1999 Sep; 163(6):2977-81. PubMed ID: 10477559
[TBL] [Abstract][Full Text] [Related]
13. Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication.
Münch J; Schindler M; Wildum S; Rücker E; Bailer N; Knoop V; Novembre FJ; Kirchhoff F
J Virol; 2005 Aug; 79(16):10547-60. PubMed ID: 16051847
[TBL] [Abstract][Full Text] [Related]
14. Two sorting motifs, a ubiquitination motif and a tyrosine motif, are involved in HIV-1 and simian immunodeficiency virus Nef-mediated receptor endocytosis.
Cai CY; Zhang X; Sinko PJ; Burakoff SJ; Jin YJ
J Immunol; 2011 May; 186(10):5807-14. PubMed ID: 21482738
[TBL] [Abstract][Full Text] [Related]
15. Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes.
Piguet V; Chen YL; Mangasarian A; Foti M; Carpentier JL; Trono D
EMBO J; 1998 May; 17(9):2472-81. PubMed ID: 9564030
[TBL] [Abstract][Full Text] [Related]
16. CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms.
Rose JJ; Janvier K; Chandrasekhar S; Sekaly RP; Bonifacino JS; Venkatesan S
J Biol Chem; 2005 Mar; 280(9):7413-26. PubMed ID: 15611114
[TBL] [Abstract][Full Text] [Related]
17. HIV and SIV Nef modulate signal transduction and protein sorting in T cells.
Skowronski J; Greenberg ME; Lock M; Mariani R; Salghetti S; Swigut T; Iafrate AJ
Cold Spring Harb Symp Quant Biol; 1999; 64():453-63. PubMed ID: 11232322
[No Abstract] [Full Text] [Related]
18. Down-modulation of CD8αβ is a fundamental activity of primate lentiviral Nef proteins.
Heigele A; Schindler M; Gnanadurai CW; Leonard JA; Collins KL; Kirchhoff F
J Virol; 2012 Jan; 86(1):36-48. PubMed ID: 22013062
[TBL] [Abstract][Full Text] [Related]
19. The T-cell receptor zeta chain contains two homologous domains with which simian immunodeficiency virus Nef interacts and mediates down-modulation.
Schaefer TM; Bell I; Fallert BA; Reinhart TA
J Virol; 2000 Apr; 74(7):3273-83. PubMed ID: 10708444
[TBL] [Abstract][Full Text] [Related]
20. Specific suppression of human CD4 surface expression by Nef from the pathogenic simian immunodeficiency virus SIVmac239open.
Foster JL; Anderson SJ; Frazier AL; Garcia JV
Virology; 1994 Jun; 201(2):373-9. PubMed ID: 8184546
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]