194 related articles for article (PubMed ID: 11289059)
1. Differential splicing of the IA-2 mRNA in pancreas and lymphoid organs as a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen.
Diez J; Park Y; Zeller M; Brown D; Garza D; Ricordi C; Hutton J; Eisenbarth GS; Pugliese A
Diabetes; 2001 Apr; 50(4):895-900. PubMed ID: 11289059
[TBL] [Abstract][Full Text] [Related]
2. Alternative splicing of G6PC2, the gene coding for the islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP), results in differential expression in human thymus and spleen compared with pancreas.
Dogra RS; Vaidyanathan P; Prabakar KR; Marshall KE; Hutton JC; Pugliese A
Diabetologia; 2006 May; 49(5):953-7. PubMed ID: 16520917
[TBL] [Abstract][Full Text] [Related]
3. IA-2 (islet cell antigen 512) is the primary target of humoral autoimmunity against type 1 diabetes-associated tyrosine phosphatase autoantigens.
Bonifacio E; Lampasona V; Bingley PJ
J Immunol; 1998 Sep; 161(5):2648-54. PubMed ID: 9725268
[TBL] [Abstract][Full Text] [Related]
4. T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents.
Honeyman MC; Stone NL; Harrison LC
Mol Med; 1998 Apr; 4(4):231-9. PubMed ID: 9606176
[TBL] [Abstract][Full Text] [Related]
5. Two distinctly HLA-associated contiguous linear epitopes uniquely expressed within the islet antigen 2 molecule are major autoantibody epitopes of the diabetes-specific tyrosine phosphatase-like protein autoantigens.
Bearzatto M; Naserke H; Piquer S; Koczwara K; Lampasona V; Williams A; Christie MR; Bingley PJ; Ziegler AG; Bonifacio E
J Immunol; 2002 Apr; 168(8):4202-8. PubMed ID: 11937581
[TBL] [Abstract][Full Text] [Related]
6. Mapping of novel autoreactive epitopes of the diabetes-associated autoantigen IA-2.
Seissler J; Schott M; Morgenthaler NG; Scherbaum WA
Clin Exp Immunol; 2000 Nov; 122(2):157-63. PubMed ID: 11091269
[TBL] [Abstract][Full Text] [Related]
7. Autoantibodies in insulin-dependent diabetes recognize distinct cytoplasmic domains of the protein tyrosine phosphatase-like IA-2 autoantigen.
Lampasona V; Bearzatto M; Genovese S; Bosi E; Ferrari M; Bonifacio E
J Immunol; 1996 Sep; 157(6):2707-11. PubMed ID: 8805677
[TBL] [Abstract][Full Text] [Related]
8. Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs.
Pugliese A; Brown D; Garza D; Murchison D; Zeller M; Redondo MJ; Diez J; Eisenbarth GS; Patel DD; Ricordi C
J Clin Invest; 2001 Mar; 107(5):555-64. PubMed ID: 11238556
[TBL] [Abstract][Full Text] [Related]
9. Early Th1 response in unprimed nonobese diabetic mice to the tyrosine phosphatase-like insulinoma-associated protein 2, an autoantigen in type 1 diabetes.
Trembleau S; Penna G; Gregori S; Magistrelli G; Isacchi A; Adorini L
J Immunol; 2000 Dec; 165(12):6748-55. PubMed ID: 11120794
[TBL] [Abstract][Full Text] [Related]
10. Human monoclonal antibodies isolated from type I diabetes patients define multiple epitopes in the protein tyrosine phosphatase-like IA-2 antigen.
Kolm-Litty V; Berlo S; Bonifacio E; Bearzatto M; Engel AM; Christie M; Ziegler AG; Wild T; Endl J
J Immunol; 2000 Oct; 165(8):4676-84. PubMed ID: 11035111
[TBL] [Abstract][Full Text] [Related]
11. Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment.
Lu J; Li Q; Xie H; Chen ZJ; Borovitskaya AE; Maclaren NK; Notkins AL; Lan MS
Proc Natl Acad Sci U S A; 1996 Mar; 93(6):2307-11. PubMed ID: 8637868
[TBL] [Abstract][Full Text] [Related]
12. Autoantigens in insulin-dependent diabetes mellitus: molecular cloning and characterization of human IA-2 beta.
Li Q; Borovitskaya AE; DeSilva MG; Wasserfall C; Maclaren NK; Notkins AL; Lan MS
Proc Assoc Am Physicians; 1997 Jul; 109(4):429-39. PubMed ID: 9220540
[TBL] [Abstract][Full Text] [Related]
13. IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus.
Lan MS; Wasserfall C; Maclaren NK; Notkins AL
Proc Natl Acad Sci U S A; 1996 Jun; 93(13):6367-70. PubMed ID: 8692821
[TBL] [Abstract][Full Text] [Related]
14. Autoantibodies to protein tyrosine phosphatase-like proteins in type I diabetes. Overlapping specificities to phogrin and ICA512/IA-2.
Kawasaki E; Eisenbarth GS; Wasmeier C; Hutton JC
Diabetes; 1996 Oct; 45(10):1344-9. PubMed ID: 8826969
[TBL] [Abstract][Full Text] [Related]
15. Humoral autoreactivity to an alternatively spliced variant of ICA512/IA-2 in Type I diabetes.
Park YS; Kawasaki E; Kelemen K; Yu L; Schiller MR; Rewers M; Mizuta M; Eisenbarth GS; Hutton JC
Diabetologia; 2000 Oct; 43(10):1293-301. PubMed ID: 11079748
[TBL] [Abstract][Full Text] [Related]
16. Detection of proteolytic cleavages of diabetes-associated protein IA-2 beta in the pancreas and the brain using novel anti-IA-2 beta monoclonal antibodies.
Kawakami T; Saeki K; Takeyama N; Wu G; Sakudo A; Matsumoto Y; Hayashi T; Onodera T
Int J Mol Med; 2007 Aug; 20(2):177-85. PubMed ID: 17611635
[TBL] [Abstract][Full Text] [Related]
17. Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).
Payton MA; Hawkes CJ; Christie MR
J Clin Invest; 1995 Sep; 96(3):1506-11. PubMed ID: 7657822
[TBL] [Abstract][Full Text] [Related]
18. Early development and spreading of autoantibodies to epitopes of IA-2 and their association with progression to type 1 diabetes.
Naserke HE; Ziegler AG; Lampasona V; Bonifacio E
J Immunol; 1998 Dec; 161(12):6963-9. PubMed ID: 9862731
[TBL] [Abstract][Full Text] [Related]
19. T-cell lines reactive to an immunodominant epitope of the tyrosine phosphatase-like autoantigen IA-2 in type 1 diabetes.
Hawkes CJ; Schloot NC; Marks J; Willemen SJ; Drijfhout JW; Mayer EK; Christie MR; Roep BO
Diabetes; 2000 Mar; 49(3):356-66. PubMed ID: 10868956
[TBL] [Abstract][Full Text] [Related]
20. Analysis of the coding and promoter regions of the autoantigen IA-2 in subjects with and without autoantibodies to IA-2.
Cai T; Xie J; She JX; Notkins AL
Diabetes; 2001 Oct; 50(10):2406-9. PubMed ID: 11574427
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]