144 related articles for article (PubMed ID: 11290604)
1. A model of human p210(bcr/ABL)-mediated chronic myelogenous leukemia by transduction of primary normal human CD34(+) cells with a BCR/ABL-containing retroviral vector.
Zhao RC; Jiang Y; Verfaillie CM
Blood; 2001 Apr; 97(8):2406-12. PubMed ID: 11290604
[TBL] [Abstract][Full Text] [Related]
2. BCR/ABL-mediated increased expression of multiple known and novel genes that may contribute to the pathogenesis of chronic myelogenous leukemia.
Salesse S; Verfaillie CM
Mol Cancer Ther; 2003 Feb; 2(2):173-82. PubMed ID: 12589034
[TBL] [Abstract][Full Text] [Related]
3. Gene therapy for chronic myelogenous leukemia (CML): a retroviral vector that renders hematopoietic progenitors methotrexate-resistant and CML progenitors functionally normal and nontumorigenic in vivo.
Zhao RC; McIvor RS; Griffin JD; Verfaillie CM
Blood; 1997 Dec; 90(12):4687-98. PubMed ID: 9389683
[TBL] [Abstract][Full Text] [Related]
4. Bcr-Abl efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: a novel model for chronic myelogenous leukemia.
Zhang X; Ren R
Blood; 1998 Nov; 92(10):3829-40. PubMed ID: 9808576
[TBL] [Abstract][Full Text] [Related]
5. BCR/ABL induces multiple abnormalities of cytoskeletal function.
Salgia R; Li JL; Ewaniuk DS; Pear W; Pisick E; Burky SA; Ernst T; Sattler M; Chen LB; Griffin JD
J Clin Invest; 1997 Jul; 100(1):46-57. PubMed ID: 9202056
[TBL] [Abstract][Full Text] [Related]
6. Abnormal integrin-mediated regulation of chronic myelogenous leukemia CD34+ cell proliferation: BCR/ABL up-regulates the cyclin-dependent kinase inhibitor, p27Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity.
Jiang Y; Zhao RC; Verfaillie CM
Proc Natl Acad Sci U S A; 2000 Sep; 97(19):10538-43. PubMed ID: 10973491
[TBL] [Abstract][Full Text] [Related]
7. Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow.
Pear WS; Miller JP; Xu L; Pui JC; Soffer B; Quackenbush RC; Pendergast AM; Bronson R; Aster JC; Scott ML; Baltimore D
Blood; 1998 Nov; 92(10):3780-92. PubMed ID: 9808572
[TBL] [Abstract][Full Text] [Related]
8. Human stem cell model to study signal transduction and molecular regulation mechanisms in CML.
Fan E; Hu Y; Zhao C
Chin Med J (Engl); 2001 Jul; 114(7):680-4. PubMed ID: 11780326
[TBL] [Abstract][Full Text] [Related]
9. Effect of mutational inactivation of tyrosine kinase activity on BCR/ABL-induced abnormalities in cell growth and adhesion in human hematopoietic progenitors.
Ramaraj P; Singh H; Niu N; Chu S; Holtz M; Yee JK; Bhatia R
Cancer Res; 2004 Aug; 64(15):5322-31. PubMed ID: 15289338
[TBL] [Abstract][Full Text] [Related]
10. Bcr-Abl has a greater intrinsic capacity than v-Abl to induce the neoplastic expansion of myeloid cells.
Gross AW; Ren R
Oncogene; 2000 Dec; 19(54):6286-96. PubMed ID: 11175343
[TBL] [Abstract][Full Text] [Related]
11. BCR/ABL-mediated downregulation of genes implicated in cell adhesion and motility leads to impaired migration toward CCR7 ligands CCL19 and CCL21 in primary BCR/ABL-positive cells.
Jongen-Lavrencic M; Salesse S; Delwel R; Verfaillie CM
Leukemia; 2005 Mar; 19(3):373-80. PubMed ID: 15674360
[TBL] [Abstract][Full Text] [Related]
12. The BCR/ABL transgene causes abnormal NK cell differentiation and can be found in circulating NK cells of advanced phase chronic myelogenous leukemia patients.
Nakajima H; Zhao R; Lund TC; Ward J; Dolan M; Hirsch B; Miller JS
J Immunol; 2002 Jan; 168(2):643-50. PubMed ID: 11777957
[TBL] [Abstract][Full Text] [Related]
13. Bcr-Abl kinase down-regulates cyclin-dependent kinase inhibitor p27 in human and murine cell lines.
Jonuleit T; van der Kuip H; Miething C; Michels H; Hallek M; Duyster J; Aulitzky WE
Blood; 2000 Sep; 96(5):1933-9. PubMed ID: 10961897
[TBL] [Abstract][Full Text] [Related]
14. Regulation of the c-jun gene in p210 BCR-ABL transformed cells corresponds with activity of JNK, the c-jun N-terminal kinase.
Burgess GS; Williamson EA; Cripe LD; Litz-Jackson S; Bhatt JA; Stanley K; Stewart MJ; Kraft AS; Nakshatri H; Boswell HS
Blood; 1998 Oct; 92(7):2450-60. PubMed ID: 9746785
[TBL] [Abstract][Full Text] [Related]
15. Rapid generation of a tetracycline-inducible BCR-ABL defective retrovirus using a single autoregulatory retroviral cassette.
Dugray A; Geay JF; Foudi A; Bonnet ML; Vainchenker W; Wendling F; Louache F; Turhan AG
Leukemia; 2001 Oct; 15(10):1658-62. PubMed ID: 11587226
[TBL] [Abstract][Full Text] [Related]
16. Role of abnormal integrin-cytoskeletal interactions in impaired beta1 integrin function in chronic myelogenous leukemia hematopoietic progenitors.
Bhatia R; Munthe HA; Verfaillie CM
Exp Hematol; 1999 Sep; 27(9):1384-96. PubMed ID: 10480429
[TBL] [Abstract][Full Text] [Related]
17. Stem cell factor as a single agent induces selective proliferation of the Philadelphia chromosome positive fraction of chronic myeloid leukemia CD34(+) cells.
Moore S; Haylock DN; Lévesque JP; McDiarmid LA; Samels LM; To LB; Simmons PJ; Hughes TP
Blood; 1998 Oct; 92(7):2461-70. PubMed ID: 9746786
[TBL] [Abstract][Full Text] [Related]
18. Growth autonomy and lineage switching in BCR-ABL-transduced human cord blood cells depend on different functional domains of BCR-ABL.
Chalandon Y; Jiang X; Loutet S; Eaves AC; Eaves CJ
Leukemia; 2004 May; 18(5):1006-12. PubMed ID: 15014528
[TBL] [Abstract][Full Text] [Related]
19. Modulation of p210(BCR-ABL) activity in transduced primary human hematopoietic cells controls lineage programming.
Chalandon Y; Jiang X; Hazlewood G; Loutet S; Conneally E; Eaves A; Eaves C
Blood; 2002 May; 99(9):3197-204. PubMed ID: 11964283
[TBL] [Abstract][Full Text] [Related]
20. The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity.
Li S; Ilaria RL; Million RP; Daley GQ; Van Etten RA
J Exp Med; 1999 May; 189(9):1399-412. PubMed ID: 10224280
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]