BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 11293550)

  • 1. A proximal tryptophan in NO synthase controls activity by a novel mechanism.
    Adak S; Stuehr DJ
    J Inorg Biochem; 2001 Feb; 83(4):301-8. PubMed ID: 11293550
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tryptophan 409 controls the activity of neuronal nitric-oxide synthase by regulating nitric oxide feedback inhibition.
    Adak S; Crooks C; Wang Q; Crane BR; Tainer JA; Getzoff ED; Stuehr DJ
    J Biol Chem; 1999 Sep; 274(38):26907-11. PubMed ID: 10480900
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular basis for hyperactivity in tryptophan 409 mutants of neuronal NO synthase.
    Adak S; Wang Q; Stuehr DJ
    J Biol Chem; 2000 Jun; 275(23):17434-9. PubMed ID: 10747960
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A tryptophan that modulates tetrahydrobiopterin-dependent electron transfer in nitric oxide synthase regulates enzyme catalysis by additional mechanisms.
    Wang ZQ; Wei CC; Santolini J; Panda K; Wang Q; Stuehr DJ
    Biochemistry; 2005 Mar; 44(12):4676-90. PubMed ID: 15779894
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of the properties of the heme-NO complexes in nitric-oxide synthase by hydrogen bonding to the proximal cysteine.
    Couture M; Adak S; Stuehr DJ; Rousseau DL
    J Biol Chem; 2001 Oct; 276(41):38280-8. PubMed ID: 11479310
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Spectroscopic characterization of five- and six-coordinate ferrous-NO heme complexes. Evidence for heme Fe-proximal cysteinate bond cleavage in the ferrous-NO adducts of the Trp-409Tyr/Phe proximal environment mutants of neuronal nitric oxide synthase.
    Voegtle HL; Sono M; Adak S; Pond AE; Tomita T; Perera R; Goodin DB; Ikeda-Saito M; Stuehr DJ; Dawson JH
    Biochemistry; 2003 Mar; 42(8):2475-84. PubMed ID: 12600215
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Roles of the heme proximal side residues tryptophan409 and tryptophan421 of neuronal nitric oxide synthase in the electron transfer reaction.
    Yumoto T; Sagami I; Daff S; Shimizu T
    J Inorg Biochem; 2000 Nov; 82(1-4):163-70. PubMed ID: 11132623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A kinetic simulation model that describes catalysis and regulation in nitric-oxide synthase.
    Santolini J; Adak S; Curran CM; Stuehr DJ
    J Biol Chem; 2001 Jan; 276(2):1233-43. PubMed ID: 11038356
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neuronal nitric-oxide synthase mutant (Ser-1412 --> Asp) demonstrates surprising connections between heme reduction, NO complex formation, and catalysis.
    Adak S; Santolini J; Tikunova S; Wang Q; Johnson JD; Stuehr DJ
    J Biol Chem; 2001 Jan; 276(2):1244-52. PubMed ID: 11038355
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A conserved tryptophan in nitric oxide synthase regulates heme-dioxy reduction by tetrahydrobiopterin.
    Wang ZQ; Wei CC; Ghosh S; Meade AL; Hemann C; Hille R; Stuehr DJ
    Biochemistry; 2001 Oct; 40(43):12819-25. PubMed ID: 11669618
    [TBL] [Abstract][Full Text] [Related]  

  • 11. C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase.
    Tiso M; Konas DW; Panda K; Garcin ED; Sharma M; Getzoff ED; Stuehr DJ
    J Biol Chem; 2005 Nov; 280(47):39208-19. PubMed ID: 16150731
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Thermodynamic and kinetic analysis of the nitrosyl, carbonyl, and dioxy heme complexes of neuronal nitric-oxide synthase. The roles of substrate and tetrahydrobiopterin in oxygen activation.
    Ost TW; Daff S
    J Biol Chem; 2005 Jan; 280(2):965-73. PubMed ID: 15507439
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of C415 mutants of neuronal nitric oxide synthase.
    Richards MK; Clague MJ; Marletta MA
    Biochemistry; 1996 Jun; 35(24):7772-80. PubMed ID: 8672477
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Electron transfer, oxygen binding, and nitric oxide feedback inhibition in endothelial nitric-oxide synthase.
    Abu-Soud HM; Ichimori K; Presta A; Stuehr DJ
    J Biol Chem; 2000 Jun; 275(23):17349-57. PubMed ID: 10749853
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of Asp-369 and Arg-372 mutations on heme environment and function in human endothelial nitric-oxide synthase.
    Chen PF; Berka V; Tsai AL; Wu KK
    J Biol Chem; 1998 Dec; 273(51):34164-70. PubMed ID: 9852077
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential effects of mutations in human endothelial nitric oxide synthase at residues Tyr-357 and Arg-365 on L-arginine hydroxylation and GN-hydroxy-L-arginine oxidation.
    Chen PF; Berka V; Wu KK
    Arch Biochem Biophys; 2003 Mar; 411(1):83-92. PubMed ID: 12590926
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A structural role for tryptophan 188 of inducible nitric oxide synthase.
    Wilson DJ; Rafferty SP
    Biochem Biophys Res Commun; 2001 Sep; 287(1):126-9. PubMed ID: 11549264
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aromatic residues and neighboring Arg414 in the (6R)-5,6,7, 8-tetrahydro-L-biopterin binding site of full-length neuronal nitric-oxide synthase are crucial in catalysis and heme reduction with NADPH.
    Sagami I; Sato Y; Daff S; Shimizu T
    J Biol Chem; 2000 Aug; 275(34):26150-7. PubMed ID: 10846172
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Exploring second coordination sphere effects in nitric oxide synthase.
    McQuarters AB; Speelman AL; Chen L; Elmore BO; Fan W; Feng C; Lehnert N
    J Biol Inorg Chem; 2016 Dec; 21(8):997-1008. PubMed ID: 27686338
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Critical role of the neuronal nitric-oxide synthase heme proximal side residue, Arg418, in catalysis and electron transfer.
    Sato Y; Sagami I; Shimizu T
    J Inorg Biochem; 2001 Dec; 87(4):261-6. PubMed ID: 11744064
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.