BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

250 related articles for article (PubMed ID: 11294897)

  • 1. Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation.
    Hart KC; Robertson SC; Donoghue DJ
    Mol Biol Cell; 2001 Apr; 12(4):931-42. PubMed ID: 11294897
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4.
    Hart KC; Robertson SC; Kanemitsu MY; Meyer AN; Tynan JA; Donoghue DJ
    Oncogene; 2000 Jul; 19(29):3309-20. PubMed ID: 10918587
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3.
    Agazie YM; Movilla N; Ischenko I; Hayman MJ
    Oncogene; 2003 Oct; 22(44):6909-18. PubMed ID: 14534538
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deregulated FGFR3 mutants in multiple myeloma cell lines with t(4;14): comparative analysis of Y373C, K650E and the novel G384D mutations.
    Ronchetti D; Greco A; Compasso S; Colombo G; Dell'Era P; Otsuki T; Lombardi L; Neri A
    Oncogene; 2001 Jun; 20(27):3553-62. PubMed ID: 11429702
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The thanatophoric dysplasia type II mutation hampers complete maturation of fibroblast growth factor receptor 3 (FGFR3), which activates signal transducer and activator of transcription 1 (STAT1) from the endoplasmic reticulum.
    Lievens PM; Liboi E
    J Biol Chem; 2003 May; 278(19):17344-9. PubMed ID: 12624096
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways.
    Guasch G; Ollendorff V; Borg JP; Birnbaum D; Pébusque MJ
    Mol Cell Biol; 2001 Dec; 21(23):8129-42. PubMed ID: 11689702
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Constitutively activated FGFR3 mutants signal through PLCgamma-dependent and -independent pathways for hematopoietic transformation.
    Chen J; Williams IR; Lee BH; Duclos N; Huntly BJ; Donoghue DJ; Gilliland DG
    Blood; 2005 Jul; 106(1):328-37. PubMed ID: 15784730
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation.
    Meyer AN; Gastwirt RF; Schlaepfer DD; Donoghue DJ
    J Biol Chem; 2004 Jul; 279(27):28450-7. PubMed ID: 15105428
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The kinase activity of fibroblast growth factor receptor 3 with activation loop mutations affects receptor trafficking and signaling.
    Lievens PM; Mutinelli C; Baynes D; Liboi E
    J Biol Chem; 2004 Oct; 279(41):43254-60. PubMed ID: 15292251
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin-like growth factor-1 rescues the mutated FGF receptor 3 (G380R) expressing ATDC5 cells from apoptosis through phosphatidylinositol 3-kinase and MAPK.
    Koike M; Yamanaka Y; Inoue M; Tanaka H; Nishimura R; Seino Y
    J Bone Miner Res; 2003 Nov; 18(11):2043-51. PubMed ID: 14606518
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells.
    Badache A; Hynes NE
    Cancer Res; 2001 Jan; 61(1):383-91. PubMed ID: 11196191
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of FGFR3, Stat1, Stat5 and p21Cip1 correlates with phenotypic severity and defective chondrocyte differentiation in FGFR3-related chondrodysplasias.
    Legeai-Mallet L; Benoist-Lasselin C; Munnich A; Bonaventure J
    Bone; 2004 Jan; 34(1):26-36. PubMed ID: 14751560
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype.
    Murakami S; Balmes G; McKinney S; Zhang Z; Givol D; de Crombrugghe B
    Genes Dev; 2004 Feb; 18(3):290-305. PubMed ID: 14871928
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells.
    Lundin Brockdorff J; Woetmann A; Mustelin T; Kaltoft K; Zhang Q; Wasik MA; Röpke C; Ødum N
    Cytokine; 2002 Nov; 20(4):141-7. PubMed ID: 12543077
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Unique signal transduction of Eyk: constitutive stimulation of the JAK-STAT pathway by an oncogenic receptor-type tyrosine kinase.
    Zong C; Yan R; August A; Darnell JE; Hanafusa H
    EMBO J; 1996 Sep; 15(17):4515-25. PubMed ID: 8887543
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.
    Smit LS; Meyer DJ; Billestrup N; Norstedt G; Schwartz J; Carter-Su C
    Mol Endocrinol; 1996 May; 10(5):519-33. PubMed ID: 8732683
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preclinical studies of fibroblast growth factor receptor 3 as a therapeutic target in multiple myeloma.
    Paterson JL; Li Z; Wen XY; Masih-Khan E; Chang H; Pollett JB; Trudel S; Stewart AK
    Br J Haematol; 2004 Mar; 124(5):595-603. PubMed ID: 14871245
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fibroblast growth factor receptor signaling activates the human interstitial collagenase promoter via the bipartite Ets-AP1 element.
    Newberry EP; Willis D; Latifi T; Boudreaux JM; Towler DA
    Mol Endocrinol; 1997 Jul; 11(8):1129-44. PubMed ID: 9212060
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antigen receptor signal transduction: activating and inhibitory antigen receptors regulate STAT1 serine phosphorylation.
    Lafont V; Decker T; Cantrell D
    Eur J Immunol; 2000 Jul; 30(7):1851-60. PubMed ID: 10940874
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins.
    Ong SH; Hadari YR; Gotoh N; Guy GR; Schlessinger J; Lax I
    Proc Natl Acad Sci U S A; 2001 May; 98(11):6074-9. PubMed ID: 11353842
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.