These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

614 related articles for article (PubMed ID: 11300876)

  • 1. Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.
    Dutta AK; Fei XS; Beardsley PM; Newman JL; Reith ME
    J Med Chem; 2001 Mar; 44(6):937-48. PubMed ID: 11300876
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.
    Dutta AK; Xu C; Reith ME
    J Med Chem; 1998 Aug; 41(17):3293-7. PubMed ID: 9703474
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters.
    Kolhatkar R; Cook CD; Ghorai SK; Deschamps J; Beardsley PM; Reith ME; Dutta AK
    J Med Chem; 2004 Oct; 47(21):5101-13. PubMed ID: 15456254
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (GBR 12935) compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules.
    Dutta AK; Davis MC; Fei XS; Beardsley PM; Cook CD; Reith ME
    J Med Chem; 2002 Jan; 45(3):654-62. PubMed ID: 11806716
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.
    Kolhatkar RB; Ghorai SK; George C; Reith ME; Dutta AK
    J Med Chem; 2003 May; 46(11):2205-15. PubMed ID: 12747792
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.
    Ghorai SK; Cook C; Davis M; Venkataraman SK; George C; Beardsley PM; Reith ME; Dutta AK
    J Med Chem; 2003 Mar; 46(7):1220-8. PubMed ID: 12646032
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SAR studies of piperidine-based analogues of cocaine. 4. Effect of N-modification and ester replacement.
    Petukhov PA; Zhang J; Kozikowski AP; Wang CZ; Ye YP; Johnson KM; Tella SR
    J Med Chem; 2002 Jul; 45(15):3161-70. PubMed ID: 12109901
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors.
    Tamiz AP; Zhang J; Flippen-Anderson JL; Zhang M; Johnson KM; Deschaux O; Tella S; Kozikowski AP
    J Med Chem; 2000 Mar; 43(6):1215-22. PubMed ID: 10737754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors.
    Tamiz AP; Bandyopadhyay BC; Zhang J; Flippen-Anderson JL; Zhang M; Wang CZ; Johnson KM; Tella S; Kozikowski AP
    J Med Chem; 2001 May; 44(10):1615-22. PubMed ID: 11334571
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationship studies of highly selective inhibitors of the dopamine transporter: N-benzylpiperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine.
    Greiner E; Prisinzano T; Johnson EM; Dersch CM; Marcus J; Partilla JS; Rothman RB; Jacobson AE; Rice KC
    J Med Chem; 2003 Apr; 46(8):1465-9. PubMed ID: 12672246
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation.
    Kulkarni SS; Grundt P; Kopajtic T; Katz JL; Newman AH
    J Med Chem; 2004 Jun; 47(13):3388-98. PubMed ID: 15189035
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity relationships at monoamine transporters and muscarinic receptors for N-substituted-3alpha-(3'-chloro-, 4'-chloro-, and 4',4''-dichloro-substituted-diphenyl)methoxytropanes.
    Newman AH; Robarge MJ; Howard IM; Wittkopp SL; George C; Kopajtic T; Izenwasser S; Katz JL
    J Med Chem; 2001 Feb; 44(4):633-40. PubMed ID: 11170654
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potent and selective ligands for the dopamine transporter (DAT): structure-activity relationship studies of novel 4-[2-(diphenylmethoxy)ethyl]-1-(3-phenylpropyl)piperidine analogues.
    Dutta AK; Coffey LL; Reith ME
    J Med Chem; 1998 Feb; 41(5):699-705. PubMed ID: 9513598
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and transporter binding properties of bridged piperazine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909).
    Zhang Y; Rothman RB; Dersch CM; de Costa BR; Jacobson AE; Rice KC
    J Med Chem; 2000 Dec; 43(25):4840-9. PubMed ID: 11123994
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile.
    Kline RH; Izenwasser S; Katz JL; Joseph DB; Bowen WD; Newman AH
    J Med Chem; 1997 Mar; 40(6):851-7. PubMed ID: 9083473
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dopamine transporter binding without cocaine-like behavioral effects: synthesis and evaluation of benztropine analogs alone and in combination with cocaine in rodents.
    Katz JL; Agoston GE; Alling KL; Kline RH; Forster MJ; Woolverton WL; Kopajtic TA; Newman AH
    Psychopharmacology (Berl); 2001 Apr; 154(4):362-74. PubMed ID: 11349389
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]- 1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity.
    Dutta AK; Coffey LL; Reith ME
    J Med Chem; 1997 Jan; 40(1):35-43. PubMed ID: 9016326
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity.
    Miller GM; Yatin SM; De La Garza R; Goulet M; Madras BK
    Brain Res Mol Brain Res; 2001 Feb; 87(1):124-43. PubMed ID: 11223167
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton.
    Kozikowski AP; Araldi GL; Boja J; Meil WM; Johnson KM; Flippen-Anderson JL; George C; Saiah E
    J Med Chem; 1998 May; 41(11):1962-9. PubMed ID: 9599245
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.
    Zhou J; Zhang A; Kläss T; Johnson KM; Wang CZ; Ye YP; Kozikowski AP
    J Med Chem; 2003 May; 46(10):1997-2007. PubMed ID: 12723962
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.