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22. Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency. Gwaltney SL; O'Connor SJ; Nelson LT; Sullivan GM; Imade H; Wang W; Hasvold L; Li Q; Cohen J; Gu WZ; Tahir SK; Bauch J; Marsh K; Ng SC; Frost DJ; Zhang H; Muchmore S; Jakob CG; Stoll V; Hutchins C; Rosenberg SH; Sham HL Bioorg Med Chem Lett; 2003 Apr; 13(7):1363-6. PubMed ID: 12657283 [TBL] [Abstract][Full Text] [Related]
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24. Potent, non-thiol inhibitors of farnesyltransferase. Breslin MJ; deSolms SJ; Giuliani EA; Stokker GE; Graham SL; Pompliano DL; Mosser SD; Hamilton KA; Hutchinson JH Bioorg Med Chem Lett; 1998 Dec; 8(23):3311-6. PubMed ID: 9873725 [TBL] [Abstract][Full Text] [Related]
25. Non-thiol farnesyltransferase inhibitors: utilization of an aryl binding site by 5-arylacryloylaminobenzophenones. Mitsch A; Böhm M; Wissner P; Sattler I; Schlitzer M Bioorg Med Chem; 2002 Aug; 10(8):2657-62. PubMed ID: 12057654 [TBL] [Abstract][Full Text] [Related]
27. Oxo-piperazine derivatives of N-arylpiperazinones as inhibitors of farnesyltransferase. Dinsmore CJ; Bergman JM; Wei DD; Zartman CB; Davide JP; Greenberg IB; Liu D; O'Neill TJ; Gibbs JB; Koblan KS; Kohl NE; Lobell RB; Chen IW; McLoughlin DA; Olah TV; Graham SL; Hartman GD; Williams TM Bioorg Med Chem Lett; 2001 Feb; 11(4):537-40. PubMed ID: 11229765 [TBL] [Abstract][Full Text] [Related]
28. Non-thiol farnesyltransferase inhibitors: utilization of the near aryl binding site by 5-arylacetylaminobenzophenones. Mitsch A; Böhm M; Sattler I; Schlitzer M Arch Pharm (Weinheim); 2004 Apr; 337(4):213-8. PubMed ID: 15065081 [TBL] [Abstract][Full Text] [Related]
29. Kurasoins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. I. Producing strain, fermentation, isolation, and biological activities. Uchida R; Shiomi K; Inokoshi J; Masuma R; Kawakubo T; Tanaka H; Iwai Y; Omura S J Antibiot (Tokyo); 1996 Sep; 49(9):932-4. PubMed ID: 8931728 [No Abstract] [Full Text] [Related]
30. Farnesyltransferase inhibitors. Adjei AA Cancer Chemother Biol Response Modif; 2001; 19():149-64. PubMed ID: 11686012 [No Abstract] [Full Text] [Related]
31. 4-methyl-1,2,4-triazol-3-yl heterocycle as an alternative to the 1-methylimidazol-5-yl moiety in the farnesyltransferase inhibitor ZARNESTRA. Angibaud P; Saha AK; Bourdrez X; End DW; Freyne E; Lezouret P; Mannens G; Mevellec L; Meyer C; Pilatte I; Poncelet V; Roux B; Smets G; Van Dun J; Venet M; Wouters W Bioorg Med Chem Lett; 2003 Dec; 13(24):4361-4. PubMed ID: 14643326 [TBL] [Abstract][Full Text] [Related]
32. Farnesyltransferase inhibitors: a new class of cancer chemotherapeutics. Koblan KS; Kohl NE; Omer CA; Anthony NJ; Conner MW; deSolms SJ; Williams TM; Graham SL; Hartman GD; Oliff A; Gibbs JB Biochem Soc Trans; 1996 Aug; 24(3):688-92. PubMed ID: 8878827 [No Abstract] [Full Text] [Related]
33. Successful virtual screening of a chemical database for farnesyltransferase inhibitor leads. Perola E; Xu K; Kollmeyer TM; Kaufmann SH; Prendergast FG; Pang YP J Med Chem; 2000 Feb; 43(3):401-8. PubMed ID: 10669567 [TBL] [Abstract][Full Text] [Related]
35. Discovery and structure-activity relationships of novel piperidine inhibitors of farnesyltransferase. Nara S; Tanaka R; Eishima J; Hara M; Takahashi Y; Otaki S; Foglesong RJ; Hughes PF; Turkington S; Kanda Y J Med Chem; 2003 Jun; 46(12):2467-73. PubMed ID: 12773050 [TBL] [Abstract][Full Text] [Related]
36. Alpha-cyanocinnamide derivatives: a new family of non-peptide, non-sulfhydryl inhibitors of Ras farnesylation. Poradosu E; Gazit A; Reuveni H; Levitzki A Bioorg Med Chem; 1999 Aug; 7(8):1727-36. PubMed ID: 10482464 [TBL] [Abstract][Full Text] [Related]
37. 3,8-Diazabicyclo[3.2.1]octan-2-one peptide mimetics: synthesis of a conformationally restricted inhibitor of farnesyltransferase. Dinsmore CJ; Bergman JM; Bogusky MJ; Culberson JC; Hamilton KA; Graham SL Org Lett; 2001 Mar; 3(6):865-8. PubMed ID: 11263902 [TBL] [Abstract][Full Text] [Related]
38. [Inhibitors of farnesyltransferase: a new approach for development of potential cancer drugs]. Schlitzer M Pharm Unserer Zeit; 1998 Nov; 27(6):278-88. PubMed ID: 9894422 [No Abstract] [Full Text] [Related]
39. Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives. Gwaltney SL; O'Connor SJ; Nelson LT; Sullivan GM; Imade H; Wang W; Hasvold L; Li Q; Cohen J; Gu WZ; Tahir SK; Bauch J; Marsh K; Ng SC; Frost DJ; Zhang H; Muchmore S; Jakob CG; Stoll V; Hutchins C; Rosenberg SH; Sham HL Bioorg Med Chem Lett; 2003 Apr; 13(7):1359-62. PubMed ID: 12657282 [TBL] [Abstract][Full Text] [Related]
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