These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Crystal structures of leukotriene A4 hydrolase in complex with captopril and two competitive tight-binding inhibitors. Thunnissen MM; Andersson B; Samuelsson B; Wong CH; Haeggström J FASEB J; 2002 Oct; 16(12):1648-50. PubMed ID: 12207002 [TBL] [Abstract][Full Text] [Related]
3. Development of a homogeneous time-resolved fluorescence leukotriene B4 assay for determining the activity of leukotriene A4 hydrolase. Liang AM; Claret E; Ouled-Diaf J; Jean A; Vogel D; Light DR; Jones SW; Guilford WJ; Parkinson JF; Snider RM J Biomol Screen; 2007 Jun; 12(4):536-45. PubMed ID: 17384330 [TBL] [Abstract][Full Text] [Related]
4. Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase. Penning TD; Chandrakumar NS; Desai BN; Djuric SW; Gasiecki AF; Liang CD; Miyashiro JM; Russell MA; Askonas LJ; Gierse JK; Harding EI; Highkin MK; Kachur JF; Kim SH; Villani-Price D; Pyla EY; Ghoreishi-Haack NS; Smith WG Bioorg Med Chem Lett; 2002 Dec; 12(23):3383-6. PubMed ID: 12419366 [TBL] [Abstract][Full Text] [Related]
5. Amino hydroxamic acids as potent inhibitors of leukotriene A4 hydrolase. Hogg JH; Ollmann IR; Haeggström JZ; Wetterholm A; Samuelsson B; Wong CH Bioorg Med Chem; 1995 Oct; 3(10):1405-15. PubMed ID: 8564408 [TBL] [Abstract][Full Text] [Related]
6. Effects of metalloproteinase inhibitors on leukotriene A4 hydrolase in human airway epithelial cells. Baker JR; Kylstra TA; Bigby TD Biochem Pharmacol; 1995 Sep; 50(7):905-12. PubMed ID: 7575672 [TBL] [Abstract][Full Text] [Related]
7. Leukotriene A4 hydrolase: mapping of a henicosapeptide involved in mechanism-based inactivation. Mueller MJ; Wetterholm A; Blomster M; Jörnvall H; Samuelsson B; Haeggström JZ Proc Natl Acad Sci U S A; 1995 Aug; 92(18):8383-7. PubMed ID: 7667299 [TBL] [Abstract][Full Text] [Related]
8. Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase. Nathaniel DJ; Evans JF; Leblanc Y; Léveillé C; Fitzsimmons BJ; Ford-Hutchinson AW Biochem Biophys Res Commun; 1985 Sep; 131(2):827-35. PubMed ID: 2996528 [TBL] [Abstract][Full Text] [Related]
9. Leukotriene A4 hydrolase. Inhibition by bestatin and intrinsic aminopeptidase activity establish its functional resemblance to metallohydrolase enzymes. Orning L; Krivi G; Fitzpatrick FA J Biol Chem; 1991 Jan; 266(3):1375-8. PubMed ID: 1846352 [TBL] [Abstract][Full Text] [Related]
10. Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor. Stsiapanava A; Olsson U; Wan M; Kleinschmidt T; Rutishauser D; Zubarev RA; Samuelsson B; Rinaldo-Matthis A; Haeggström JZ Proc Natl Acad Sci U S A; 2014 Mar; 111(11):4227-32. PubMed ID: 24591641 [TBL] [Abstract][Full Text] [Related]
11. Evidence for a catalytic role of tyrosine 383 in the peptidase reaction of leukotriene A4 hydrolase. Blomster M; Wetterholm A; Mueller MJ; Haeggström JZ Eur J Biochem; 1995 Aug; 231(3):528-34. PubMed ID: 7649151 [TBL] [Abstract][Full Text] [Related]
12. Potent and selective inhibitors of leukotriene A4 hydrolase: effects on purified enzyme and human polymorphonuclear leukocytes. Wetterholm A; Haeggström JZ; Samuelsson B; Yuan W; Munoz B; Wong CH J Pharmacol Exp Ther; 1995 Oct; 275(1):31-7. PubMed ID: 7562564 [TBL] [Abstract][Full Text] [Related]
13. Identification and subcellular localization of leukotriene A4-hydrolase activity in human epidermis. Iversen L; Ziboh VA; Shimizu T; Ohishi N; Rådmark O; Wetterholm A; Kragballe K J Dermatol Sci; 1994 Jun; 7(3):191-201. PubMed ID: 7918238 [TBL] [Abstract][Full Text] [Related]
14. Leukotriene A4 hydrolase: protection from mechanism-based inactivation by mutation of tyrosine-378. Mueller MJ; Blomster M; Oppermann UC; Jörnvall H; Samuelsson B; Haeggström JZ Proc Natl Acad Sci U S A; 1996 Jun; 93(12):5931-5. PubMed ID: 8650196 [TBL] [Abstract][Full Text] [Related]