643 related articles for article (PubMed ID: 11312355)
1. Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2001 May; 75(10):4832-42. PubMed ID: 11312355
[TBL] [Abstract][Full Text] [Related]
2. Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Sep; 76(18):9143-51. PubMed ID: 12186898
[TBL] [Abstract][Full Text] [Related]
3. Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision.
Boyer PL; Imamichi T; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2004 Sep; 78(18):9987-97. PubMed ID: 15331732
[TBL] [Abstract][Full Text] [Related]
4. The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Apr; 76(7):3248-56. PubMed ID: 11884549
[TBL] [Abstract][Full Text] [Related]
5. Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir.
Marchand B; White KL; Ly JK; Margot NA; Wang R; McDermott M; Miller MD; Götte M
Antimicrob Agents Chemother; 2007 Aug; 51(8):2911-9. PubMed ID: 17517852
[TBL] [Abstract][Full Text] [Related]
6. Mechanistic basis of zidovudine hypersusceptibility and lamivudine resistance conferred by the deletion of codon 69 in the HIV-1 reverse transcriptase coding region.
Kisic M; Mendieta J; Puertas MC; Parera M; Martínez MA; Martinez-Picado J; Menéndez-Arias L
J Mol Biol; 2008 Oct; 382(2):327-41. PubMed ID: 18662701
[TBL] [Abstract][Full Text] [Related]
7. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
Kerr SG; Anderson KS
Biochemistry; 1997 Nov; 36(46):14064-70. PubMed ID: 9369478
[TBL] [Abstract][Full Text] [Related]
8. Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis.
Ray AS; Murakami E; Basavapathruni A; Vaccaro JA; Ulrich D; Chu CK; Schinazi RF; Anderson KS
Biochemistry; 2003 Jul; 42(29):8831-41. PubMed ID: 12873144
[TBL] [Abstract][Full Text] [Related]
9. 3'-Azido-3'-deoxythymidine-(5')-tetraphospho-(5')-adenosine, the product of ATP-mediated excision of chain-terminating AZTMP, is a potent chain-terminating substrate for HIV-1 reverse transcriptase.
Dharmasena S; Pongracz Z; Arnold E; Sarafianos SG; Parniak MA
Biochemistry; 2007 Jan; 46(3):828-36. PubMed ID: 17223704
[TBL] [Abstract][Full Text] [Related]
10. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase.
Gao HQ; Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Mol Biol; 2000 Jul; 300(2):403-18. PubMed ID: 10873473
[TBL] [Abstract][Full Text] [Related]
11. Mutational patterns associated with the 69 insertion complex in multi-drug-resistant HIV-1 reverse transcriptase that confer increased excision activity and high-level resistance to zidovudine.
Cases-González CE; Franco S; Martínez MA; Menéndez-Arias L
J Mol Biol; 2007 Jan; 365(2):298-309. PubMed ID: 17070543
[TBL] [Abstract][Full Text] [Related]
12. Structural basis of HIV-1 resistance to AZT by excision.
Tu X; Das K; Han Q; Bauman JD; Clark AD; Hou X; Frenkel YV; Gaffney BL; Jones RA; Boyer PL; Hughes SH; Sarafianos SG; Arnold E
Nat Struct Mol Biol; 2010 Oct; 17(10):1202-9. PubMed ID: 20852643
[TBL] [Abstract][Full Text] [Related]
13. Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
Canard B; Sarfati SR; Richardson CC
J Biol Chem; 1998 Jun; 273(23):14596-604. PubMed ID: 9603976
[TBL] [Abstract][Full Text] [Related]
14. Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.
Krebs R; Immendörfer U; Thrall SH; Wöhrl BM; Goody RS
Biochemistry; 1997 Aug; 36(33):10292-300. PubMed ID: 9254628
[TBL] [Abstract][Full Text] [Related]
15. Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance.
Mas A; Parera M; Briones C; Soriano V; Martínez MA; Domingo E; Menéndez-Arias L
EMBO J; 2000 Nov; 19(21):5752-61. PubMed ID: 11060026
[TBL] [Abstract][Full Text] [Related]
16. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
Periclou AP; Nandy P; Avramis VI
In Vivo; 2000; 14(3):377-88. PubMed ID: 10904870
[TBL] [Abstract][Full Text] [Related]
17. Mutational patterns in the HIV genome and cross-resistance following nucleoside and nucleotide analogue drug exposure.
Miller V; Larder BA
Antivir Ther; 2001; 6 Suppl 3():25-44. PubMed ID: 11678471
[TBL] [Abstract][Full Text] [Related]
18. Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance.
Tantillo C; Ding J; Jacobo-Molina A; Nanni RG; Boyer PL; Hughes SH; Pauwels R; Andries K; Janssen PA; Arnold E
J Mol Biol; 1994 Oct; 243(3):369-87. PubMed ID: 7525966
[TBL] [Abstract][Full Text] [Related]
19. Non-nucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3'-azido-3'-deoxythymidine (AZT)-resistant polymerase to AZT-5'-triphosphate.
Odriozola L; Cruchaga C; Andréola M; Dollé V; Nguyen CH; Tarrago-Litvak L; Pérez-Mediavilla A; Martínez-Irujo JJ
J Biol Chem; 2003 Oct; 278(43):42710-6. PubMed ID: 12917424
[TBL] [Abstract][Full Text] [Related]
20. Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants.
Lennerstrand J; Hertogs K; Stammers DK; Larder BA
J Virol; 2001 Aug; 75(15):7202-5. PubMed ID: 11435603
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]