These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
127 related articles for article (PubMed ID: 11312920)
1. Novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 2. Mechanism of inhibition and structure-based improvement of pharmaceutical properties. Liu G; Huth JR; Olejniczak ET; Mendoza R; DeVries P; Leitza S; Reilly EB; Okasinski GF; Fesik SW; von Geldern TW J Med Chem; 2001 Apr; 44(8):1202-10. PubMed ID: 11312920 [TBL] [Abstract][Full Text] [Related]
2. Discovery of potent antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 3. Amide (C-ring) structure-activity relationship and improvement of overall properties of arylthio cinnamides. Pei Z; Xin Z; Liu G; Li Y; Reilly EB; Lubbers NL; Huth JR; Link JT; von Geldern TW; Cox BF; Leitza S; Gao Y; Marsh KC; DeVries P; Okasinski GF J Med Chem; 2001 Aug; 44(18):2913-20. PubMed ID: 11520199 [TBL] [Abstract][Full Text] [Related]
3. Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 4. Structure-activity relationship of substituents on the benzene ring of the cinnamide. Winn M; Reilly EB; Liu G; Huth JR; Jae HS; Freeman J; Pei Z; Xin Z; Lynch J; Kester J; von Geldern TW; Leitza S; DeVries P; Dickinson R; Mussatto D; Okasinski GF J Med Chem; 2001 Dec; 44(25):4393-403. PubMed ID: 11728185 [TBL] [Abstract][Full Text] [Related]
4. Structure of an allosteric inhibitor of LFA-1 bound to the I-domain studied by crystallography, NMR, and calorimetry. Crump MP; Ceska TA; Spyracopoulos L; Henry A; Archibald SC; Alexander R; Taylor RJ; Findlow SC; O'Connell J; Robinson MK; Shock A Biochemistry; 2004 Mar; 43(9):2394-404. PubMed ID: 14992576 [TBL] [Abstract][Full Text] [Related]
5. NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding. Huth JR; Olejniczak ET; Mendoza R; Liang H; Harris EA; Lupher ML; Wilson AE; Fesik SW; Staunton DE Proc Natl Acad Sci U S A; 2000 May; 97(10):5231-6. PubMed ID: 10805782 [TBL] [Abstract][Full Text] [Related]
6. Competition between intercellular adhesion molecule-1 and a small-molecule antagonist for a common binding site on the alphal subunit of lymphocyte function-associated antigen-1. Keating SM; Clark KR; Stefanich LD; Arellano F; Edwards CP; Bodary SC; Spencer SA; Gadek TR; Marsters JC; Beresini MH Protein Sci; 2006 Feb; 15(2):290-303. PubMed ID: 16384997 [TBL] [Abstract][Full Text] [Related]
7. Amino-substituted heterocycles as isosteres of trans-cinnamides: design and synthesis of heterocyclic biaryl sulfides as potent antagonists of LFA-1/ICAM-1 binding. Wang GT; Wang S; Gentles R; Sowin T; Leitza S; Reilly EB; von Geldern TW Bioorg Med Chem Lett; 2005 Jan; 15(1):195-201. PubMed ID: 15582439 [TBL] [Abstract][Full Text] [Related]
8. Cellular activation of leukocyte function-associated antigen-1 and its affinity are regulated at the I domain allosteric site. Lupher ML; Harris EA; Beals CR; Sui LM; Liddington RC; Staunton DE J Immunol; 2001 Aug; 167(3):1431-9. PubMed ID: 11466362 [TBL] [Abstract][Full Text] [Related]
9. A peptide derived from LFA-1 protein that modulates T-cell adhesion binds to soluble ICAM-1 protein. Jois SD; Teruna TJ J Biomol Struct Dyn; 2003 Apr; 20(5):635-44. PubMed ID: 12643766 [TBL] [Abstract][Full Text] [Related]
10. QSAR study on some p-arylthio cinnamides as antagonists of biochemical ICAM-1/LFA-1 interaction and ICAM-1/JY-8 cell adhesion in relation to anti-inflammatory activity. Debnath B; Samanta S; Roy K; Jha T Bioorg Med Chem; 2003 Apr; 11(8):1615-9. PubMed ID: 12659746 [TBL] [Abstract][Full Text] [Related]
11. Dynamic control of allosteric antagonism of leukocyte function antigen-1 and intercellular adhesion molecule-1 interaction. Nam K; Maiorov V; Feuston B; Kearsley S Proteins; 2006 Aug; 64(2):376-84. PubMed ID: 16705652 [TBL] [Abstract][Full Text] [Related]
12. The second domain of intercellular adhesion molecule-1 (ICAM-1) maintains the structural integrity of the leucocyte function-associated antigen-1 (LFA-1) ligand-binding site in the first domain. Stanley P; McDowall A; Bates PA; Brashaw J; Hogg N Biochem J; 2000 Oct; 351(Pt 1):79-86. PubMed ID: 10998349 [TBL] [Abstract][Full Text] [Related]
14. Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 1. Identification of an additional binding pocket based on an anilino diaryl sulfide lead. Liu G; Link JT; Pei Z; Reilly EB; Leitza S; Nguyen B; Marsh KC; Okasinski GF; von Geldern TW; Ormes M; Fowler K; Gallatin M J Med Chem; 2000 Oct; 43(21):4025-40. PubMed ID: 11052808 [TBL] [Abstract][Full Text] [Related]
15. Characterization of binding properties of ICAM-1 peptides to LFA-1: inhibitors of T-cell adhesion. Anderson ME; Tejo BA; Yakovleva T; Siahaan TJ Chem Biol Drug Des; 2006 Jul; 68(1):20-8. PubMed ID: 16923022 [TBL] [Abstract][Full Text] [Related]
16. Inhibitors targeting the LFA-1/ICAM-1 cell-adhesion interaction: design and mechanism of action. Zimmerman T; Blanco FJ Curr Pharm Des; 2008; 14(22):2128-39. PubMed ID: 18781967 [TBL] [Abstract][Full Text] [Related]
17. Structural and ICAM-1-docking properties of a cyclic peptide from the I-domain of LFA-1: an inhibitor of ICAM-1/LFA- 1-mediated T-cell adhesion. Xu CR; Yusuf-Makagiansar H; Hu Y; Jois SD; Siahaan TJ J Biomol Struct Dyn; 2002 Apr; 19(5):789-99. PubMed ID: 11922836 [TBL] [Abstract][Full Text] [Related]
18. Dimerization and the effectiveness of ICAM-1 in mediating LFA-1-dependent adhesion. Jun CD; Shimaoka M; Carman CV; Takagi J; Springer TA Proc Natl Acad Sci U S A; 2001 Jun; 98(12):6830-5. PubMed ID: 11391003 [TBL] [Abstract][Full Text] [Related]
19. Intercellular adhesion molecule-1 dimerization and its consequences for adhesion mediated by lymphocyte function associated-1. Miller J; Knorr R; Ferrone M; Houdei R; Carron CP; Dustin ML J Exp Med; 1995 Nov; 182(5):1231-41. PubMed ID: 7595194 [TBL] [Abstract][Full Text] [Related]
20. Force spectroscopy of LFA-1 and its ligands, ICAM-1 and ICAM-2. Wojcikiewicz EP; Abdulreda MH; Zhang X; Moy VT Biomacromolecules; 2006 Nov; 7(11):3188-95. PubMed ID: 17096550 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]