390 related articles for article (PubMed ID: 11313365)
1. Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343.
Persad S; Attwell S; Gray V; Mawji N; Deng JT; Leung D; Yan J; Sanghera J; Walsh MP; Dedhar S
J Biol Chem; 2001 Jul; 276(29):27462-9. PubMed ID: 11313365
[TBL] [Abstract][Full Text] [Related]
2. Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation.
Troussard AA; Mawji NM; Ong C; Mui A; St -Arnaud R; Dedhar S
J Biol Chem; 2003 Jun; 278(25):22374-8. PubMed ID: 12686550
[TBL] [Abstract][Full Text] [Related]
3. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase.
Delcommenne M; Tan C; Gray V; Rue L; Woodgett J; Dedhar S
Proc Natl Acad Sci U S A; 1998 Sep; 95(19):11211-6. PubMed ID: 9736715
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells.
Persad S; Attwell S; Gray V; Delcommenne M; Troussard A; Sanghera J; Dedhar S
Proc Natl Acad Sci U S A; 2000 Mar; 97(7):3207-12. PubMed ID: 10716737
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth.
Edwards LA; Thiessen B; Dragowska WH; Daynard T; Bally MB; Dedhar S
Oncogene; 2005 May; 24(22):3596-605. PubMed ID: 15782140
[TBL] [Abstract][Full Text] [Related]
6. Integrin-linked kinase (ILK): a "hot" therapeutic target.
Yoganathan TN; Costello P; Chen X; Jabali M; Yan J; Leung D; Zhang Z; Yee A; Dedhar S; Sanghera J
Biochem Pharmacol; 2000 Oct; 60(8):1115-9. PubMed ID: 11007949
[TBL] [Abstract][Full Text] [Related]
7. Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival.
Troussard AA; McDonald PC; Wederell ED; Mawji NM; Filipenko NR; Gelmon KA; Kucab JE; Dunn SE; Emerman JT; Bally MB; Dedhar S
Cancer Res; 2006 Jan; 66(1):393-403. PubMed ID: 16397254
[TBL] [Abstract][Full Text] [Related]
8. Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1.
Wick MJ; Dong LQ; Riojas RA; Ramos FJ; Liu F
J Biol Chem; 2000 Dec; 275(51):40400-6. PubMed ID: 11006271
[TBL] [Abstract][Full Text] [Related]
9. Caenorhabditis elegans PIAK, a phospholipid-independent kinase that activates the AKT/PKB survival kinase.
Li Y; Dowbenko D; Lasky LA
J Biol Chem; 2001 Jun; 276(23):20323-9. PubMed ID: 11274160
[TBL] [Abstract][Full Text] [Related]
10. Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1.
Hill MM; Feng J; Hemmings BA
Curr Biol; 2002 Jul; 12(14):1251-5. PubMed ID: 12176337
[TBL] [Abstract][Full Text] [Related]
11. Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway.
Nho RS; Xia H; Kahm J; Kleidon J; Diebold D; Henke CA
J Biol Chem; 2005 Jul; 280(28):26630-9. PubMed ID: 15905178
[TBL] [Abstract][Full Text] [Related]
12. Developmental regulation of protein kinase B activation is isoform specific in skeletal muscle of neonatal pigs.
Suryawan A; Davis TA
Pediatr Res; 2005 Oct; 58(4):719-24. PubMed ID: 16189199
[TBL] [Abstract][Full Text] [Related]
13. Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.
Jiang ZY; Zhou QL; Holik J; Patel S; Leszyk J; Coleman K; Chouinard M; Czech MP
J Biol Chem; 2005 Jun; 280(22):21622-8. PubMed ID: 15799971
[TBL] [Abstract][Full Text] [Related]
14. Heart 6-phosphofructo-2-kinase activation by insulin results from Ser-466 and Ser-483 phosphorylation and requires 3-phosphoinositide-dependent kinase-1, but not protein kinase B.
Bertrand L; Alessi DR; Deprez J; Deak M; Viaene E; Rider MH; Hue L
J Biol Chem; 1999 Oct; 274(43):30927-33. PubMed ID: 10521487
[TBL] [Abstract][Full Text] [Related]
15. Protein kinase B is regulated in platelets by the collagen receptor glycoprotein VI.
Barry FA; Gibbins JM
J Biol Chem; 2002 Apr; 277(15):12874-8. PubMed ID: 11825911
[TBL] [Abstract][Full Text] [Related]
16. The integrin-linked kinase (ILK) suppresses anoikis.
Attwell S; Roskelley C; Dedhar S
Oncogene; 2000 Aug; 19(33):3811-5. PubMed ID: 10949937
[TBL] [Abstract][Full Text] [Related]
17. Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma.
Koul D; Shen R; Bergh S; Lu Y; de Groot JF; Liu TJ; Mills GB; Yung WK
Mol Cancer Ther; 2005 Nov; 4(11):1681-8. PubMed ID: 16275989
[TBL] [Abstract][Full Text] [Related]
18. Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines.
Lee SL; Chou CC; Chuang HC; Hsu EC; Chiu PC; Kulp SK; Byrd JC; Chen CS
PLoS One; 2013; 8(6):e67149. PubMed ID: 23840605
[TBL] [Abstract][Full Text] [Related]
19. AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival.
Li Y; Dowbenko D; Lasky LA
J Biol Chem; 2002 Mar; 277(13):11352-61. PubMed ID: 11756412
[TBL] [Abstract][Full Text] [Related]
20. Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.
McDonald PC; Oloumi A; Mills J; Dobreva I; Maidan M; Gray V; Wederell ED; Bally MB; Foster LJ; Dedhar S
Cancer Res; 2008 Mar; 68(6):1618-24. PubMed ID: 18339839
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
