151 related articles for article (PubMed ID: 11316875)
1. High-resolution crystal structure of deoxy hemoglobin complexed with a potent allosteric effector.
Safo MK; Moure CM; Burnett JC; Joshi GS; Abraham DJ
Protein Sci; 2001 May; 10(5):951-7. PubMed ID: 11316875
[TBL] [Abstract][Full Text] [Related]
2. Allosteric modifiers of hemoglobin: 2-[4-[[(3,5-disubstituted anilino)carbonyl]methyl]phenoxy]-2-methylpropionic acid derivatives that lower the oxygen affinity of hemoglobin in red cell suspensions, in whole blood, and in vivo in rats.
Abraham DJ; Wireko FC; Randad RS; Poyart C; Kister J; Bohn B; Liard JF; Kunert MP
Biochemistry; 1992 Sep; 31(38):9141-9. PubMed ID: 1390701
[TBL] [Abstract][Full Text] [Related]
3. X-ray crystallographic analyses of symmetrical allosteric effectors of hemoglobin: compounds designed to link primary and secondary binding sites.
Safo MK; Boyiri T; Burnett JC; Danso-Danquah R; Moure CM; Joshi GS; Abraham DJ
Acta Crystallogr D Biol Crystallogr; 2002 Apr; 58(Pt 4):634-44. PubMed ID: 11914488
[TBL] [Abstract][Full Text] [Related]
4. Aryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of Hemoglobin.
Omar AM; Mahran MA; Ghatge MS; Bamane FH; Ahmed MH; El-Araby ME; Abdulmalik O; Safo MK
Molecules; 2016 Aug; 21(8):. PubMed ID: 27529207
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and structure-activity relationships of chiral allosteric modifiers of hemoglobin.
Phelps Grella M; Danso-Danquah R; Safo MK; Joshi GS; Kister J; Marden M; Hoffman SJ; Abraham DJ
J Med Chem; 2000 Dec; 43(25):4726-37. PubMed ID: 11123981
[TBL] [Abstract][Full Text] [Related]
6. Allosteric modifiers of hemoglobin. 1. Design, synthesis, testing, and structure-allosteric activity relationship of novel hemoglobin oxygen affinity decreasing agents.
Randad RS; Mahran MA; Mehanna AS; Abraham DJ
J Med Chem; 1991 Feb; 34(2):752-7. PubMed ID: 1995897
[TBL] [Abstract][Full Text] [Related]
7. Phase I trial to determine the safety, pharmacodynamics, and pharmacokinetics of RSR13, a novel radioenhancer, in newly diagnosed glioblastoma multiforme.
Kleinberg L; Grossman SA; Piantadosi S; Pearlman J; Engelhard H; Lesser G; Ruffer J; Gerber M
J Clin Oncol; 1999 Aug; 17(8):2593-603. PubMed ID: 10561327
[TBL] [Abstract][Full Text] [Related]
8. RSR13, a synthetic allosteric modifier of hemoglobin, improves myocardial recovery following hypothermic cardiopulmonary bypass.
Kilgore KS; Shwartz CF; Gallagher MA; Steffen RP; Mosca RS; Bolling SF
Circulation; 1999 Nov; 100(19 Suppl):II351-6. PubMed ID: 10567328
[TBL] [Abstract][Full Text] [Related]
9. Effect of an allosteric modifier of hemoglobin, RSR-4, on oxygen affinity and oxygen saturation of hemoglobin in rabbits.
Uchida K; Reilly MP; Abraham DJ; Asakura T
Jpn J Physiol; 1998 Dec; 48(6):439-44. PubMed ID: 10021497
[TBL] [Abstract][Full Text] [Related]
10. Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease.
Pagare PP; Ghatge MS; Musayev FN; Deshpande TM; Chen Q; Braxton C; Kim S; Venitz J; Zhang Y; Abdulmalik O; Safo MK
Bioorg Med Chem; 2018 May; 26(9):2530-2538. PubMed ID: 29655608
[TBL] [Abstract][Full Text] [Related]
11. Allosteric effectors of hemoglobin as modulators of chemotherapy and radiation therapy in vitro and in vivo.
Teicher BA; Wong JS; Takeuchi H; Gravelin LM; Ara G; Buxton D
Cancer Chemother Pharmacol; 1998; 42(1):24-30. PubMed ID: 9619754
[TBL] [Abstract][Full Text] [Related]
12. Synthesized allosteric effectors of the hemoglobin molecule: a possible mechanism for improved erythrocyte oxygen release capability in hemoglobinopathy H disease.
Papassotiriou I; Kister J; Griffon N; Abraham DJ; Kanavakis E; Traeger-Synodinos J; Stamoulakatou A; Marden MC; Poyart C
Exp Hematol; 1998 Sep; 26(10):922-6. PubMed ID: 9728926
[TBL] [Abstract][Full Text] [Related]
13. Insights into the solution structure of human deoxyhemoglobin in the absence and presence of an allosteric effector.
Sahu SC; Simplaceanu V; Gong Q; Ho NT; Tian F; Prestegard JH; Ho C
Biochemistry; 2007 Sep; 46(35):9973-80. PubMed ID: 17691822
[TBL] [Abstract][Full Text] [Related]
14. Effects of the allosteric modification of hemoglobin on brain oxygen and infarct size in a feline model of stroke.
Watson JC; Doppenberg EM; Bullock MR; Zauner A; Rice MR; Abraham D; Young HF
Stroke; 1997 Aug; 28(8):1624-30. PubMed ID: 9259760
[TBL] [Abstract][Full Text] [Related]
15. Structural basis for the potent antisickling effect of a novel class of five-membered heterocyclic aldehydic compounds.
Safo MK; Abdulmalik O; Danso-Danquah R; Burnett JC; Nokuri S; Joshi GS; Musayev FN; Asakura T; Abraham DJ
J Med Chem; 2004 Sep; 47(19):4665-76. PubMed ID: 15341482
[TBL] [Abstract][Full Text] [Related]
16. The crystal structure of bar-headed goose hemoglobin in deoxy form: the allosteric mechanism of a hemoglobin species with high oxygen affinity.
Liang Y; Hua Z; Liang X; Xu Q; Lu G
J Mol Biol; 2001 Oct; 313(1):123-37. PubMed ID: 11601851
[TBL] [Abstract][Full Text] [Related]
17. RSR13, a synthetic allosteric modifier of hemoglobin, enhances recovery of stunned myocardium in dogs.
Pagel PS; Hettrick DA; Montgomery MW; Kersten JR; Warltier DC
Adv Exp Med Biol; 1998; 454():527-31. PubMed ID: 9889932
[No Abstract] [Full Text] [Related]
18. Crystal structures of HbA2 and HbE and modeling of hemoglobin delta 4: interpretation of the thermal stability and the antisickling effect of HbA2 and identification of the ferrocyanide binding site in Hb.
Sen U; Dasgupta J; Choudhury D; Datta P; Chakrabarti A; Chakrabarty SB; Chakrabarty A; Dattagupta JK
Biochemistry; 2004 Oct; 43(39):12477-88. PubMed ID: 15449937
[TBL] [Abstract][Full Text] [Related]
19. RSR13, an allosteric effector of haemoglobin, and carbogen radiosensitize FSAII and SCCVII tumours in C3H mice.
Khandelwal SR; Kavanagh BD; Lin PS; Truong QT; Lu J; Abraham DJ; Schmidt-Ullrich RK
Br J Cancer; 1999 Feb; 79(5-6):814-20. PubMed ID: 10070874
[TBL] [Abstract][Full Text] [Related]
20. X-ray diffraction study of di and tetra-ligated T-state hemoglobin from high salt crystals.
Abraham DJ; Peascoe RA; Randad RS; Panikker J
J Mol Biol; 1992 Sep; 227(2):480-92. PubMed ID: 1404365
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
