BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 11318417)

  • 1. High-performance liquid chromatography assay for simultaneous determination of dextromethorphan and its main metabolites in urine and in microsomal preparations.
    Bendriss EK; Markoglou N; Wainer IW
    J Chromatogr B Biomed Sci Appl; 2001 Apr; 754(1):209-15. PubMed ID: 11318417
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A validated SIM GC/MS method for the simultaneous determination of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in biological matrices and its application to in vitro CYP2D6 and CYP3A4 inhibition study.
    Spanakis M; Vizirianakis IS; Mironidou-Tzouveleki M; Niopas I
    Biomed Chromatogr; 2009 Nov; 23(11):1131-7. PubMed ID: 19444798
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A sensitive LC-MS/MS assay for the determination of dextromethorphan and metabolites in human urine--application for drug interaction studies assessing potential CYP3A and CYP2D6 inhibition.
    Vengurlekar SS; Heitkamp J; McCush F; Velagaleti PR; Brisson JH; Bramer SL
    J Pharm Biomed Anal; 2002 Aug; 30(1):113-24. PubMed ID: 12151071
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?
    Yu A; Haining RL
    Drug Metab Dispos; 2001 Nov; 29(11):1514-20. PubMed ID: 11602530
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dextromethorphan as an in vivo probe for the simultaneous determination of CYP2D6 and CYP3A activity.
    Ducharme J; Abdullah S; Wainer IW
    J Chromatogr B Biomed Appl; 1996 Mar; 678(1):113-28. PubMed ID: 8861661
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A.
    von Moltke LL; Greenblatt DJ; Grassi JM; Granda BW; Venkatakrishnan K; Schmider J; Harmatz JS; Shader RI
    J Pharm Pharmacol; 1998 Sep; 50(9):997-1004. PubMed ID: 9811160
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Validation of a liquid chromatography-mass spectrometry method to assess the metabolism of dextromethorphan in rat everted gut sacs.
    Arellano C; Philibert C; Dane à Yakan EN; Vachoux C; Lacombe O; Woodley J; Houin G
    J Chromatogr B Analyt Technol Biomed Life Sci; 2005 May; 819(1):105-13. PubMed ID: 15797528
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantification of dextromethorphan and metabolites: a dual phenotypic marker for cytochrome P450 3A4/5 and 2D6 activity.
    Jones DR; Gorski JC; Hamman MA; Hall SD
    J Chromatogr B Biomed Appl; 1996 Mar; 678(1):105-11. PubMed ID: 8861660
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Simultaneous determination of dextromethorphan and three metabolites in plasma and urine using high-performance liquid chromatography with application to their disposition in man.
    Chen ZR; Somogyi AA; Bochner F
    Ther Drug Monit; 1990 Jan; 12(1):97-104. PubMed ID: 2305428
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modified high-performance liquid chromatographic method to measure both dextromethorphan and proguanil for oxidative phenotyping.
    Hoskins JM; Shenfield GM; Gross AS
    J Chromatogr B Biomed Sci Appl; 1997 Aug; 696(1):81-7. PubMed ID: 9300912
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development and validation of a chemical hydrolysis method for dextromethorphan and dextrophan determination in urine samples: application to the assessment of CYP2D6 activity in fibromyalgia patients.
    Daali Y; Cherkaoui S; Doffey-Lazeyras F; Dayer P; Desmeules JA
    J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Jan; 861(1):56-63. PubMed ID: 18065299
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Single-point plasma or urine dextromethorphan method for determining CYP3A activity.
    Kuo BP; Hu OY; Hsiong CH; Pao LH; Chen TS; Hung CF
    Biopharm Drug Dispos; 2003 Dec; 24(9):367-73. PubMed ID: 14689465
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A urine metabolic ratio of dextromethorphan and 3-methoxymorphinan as a probe for CYP3A activity and prediction of cyclosporine clearance in healthy volunteers.
    Min DI; Ku YM; Vichiendilokkul A; Fleckenstein LL
    Pharmacotherapy; 1999 Jun; 19(6):753-9. PubMed ID: 10391422
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation.
    Jones DR; Gorski JC; Haehner BD; O'Mara EM; Hall SD
    Clin Pharmacol Ther; 1996 Oct; 60(4):374-84. PubMed ID: 8873685
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of a chromatographic bioreactor based on immobilized beta-glucuronidase on monolithic support for the determination of dextromethorphan and dextrorphan in human urine.
    Calleri E; Marrubini G; Massolini G; Lubda D; de Fazio SS; Furlanetto S; Wainer IW; Manzo L; Caccialanza G
    J Pharm Biomed Anal; 2004 Sep; 35(5):1179-89. PubMed ID: 15336363
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High-performance liquid chromatography determination of dextromethorphan and dextrorphan for oxidation phenotyping by fluorescence and ultraviolet detection.
    Lam YW; Rodriguez SY
    Ther Drug Monit; 1993 Aug; 15(4):300-4. PubMed ID: 8236365
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Simultaneous analysis of dextromethorphan and its three metabolites in human plasma using an improved HPLC method with fluorometric detection.
    Lin SY; Chen CH; Ho HO; Chen HH; Sheu MT
    J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Nov; 859(1):141-6. PubMed ID: 17919999
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of black seed on dextromethorphan O- and N-demethylation in human liver microsomes and healthy human subjects.
    Al-Jenoobi FI; Al-Thukair AA; Abbas FA; Ansari MJ; Alkharfy KM; Al-Mohizea AM; Al-Suwayeh SA; Jamil S
    Drug Metab Lett; 2010 Jan; 4(1):51-5. PubMed ID: 20201775
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An automated, high-throughput, 384 well Cytochrome P450 cocktail IC50 assay using a rapid resolution LC-MS/MS end-point.
    Youdim KA; Lyons R; Payne L; Jones BC; Saunders K
    J Pharm Biomed Anal; 2008 Sep; 48(1):92-9. PubMed ID: 18584988
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: the role of gut CYP3A and P-glycoprotein.
    Di Marco MP; Edwards DJ; Wainer IW; Ducharme MP
    Life Sci; 2002 Jul; 71(10):1149-60. PubMed ID: 12095536
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.