BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 11327196)

  • 1. The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein.
    Zhang Y; Benet LZ
    Clin Pharmacokinet; 2001; 40(3):159-68. PubMed ID: 11327196
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The drug efflux-metabolism alliance: biochemical aspects.
    Benet LZ; Cummins CL
    Adv Drug Deliv Rev; 2001 Oct; 50 Suppl 1():S3-11. PubMed ID: 11576692
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transport proteins and intestinal metabolism: P-glycoprotein and cytochrome P4503A.
    Christians U
    Ther Drug Monit; 2004 Apr; 26(2):104-6. PubMed ID: 15228147
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics.
    Wacher VJ; Silverman JA; Zhang Y; Benet LZ
    J Pharm Sci; 1998 Nov; 87(11):1322-30. PubMed ID: 9811484
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine.
    Suzuki H; Sugiyama Y
    Eur J Pharm Sci; 2000 Nov; 12(1):3-12. PubMed ID: 11121729
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of human CYP3A and P-glycoprotein on the absorption of drugs.
    van de Waterbeemd H
    Eur J Pharm Sci; 2000 Nov; 12(1):1. PubMed ID: 11121728
    [No Abstract]   [Full Text] [Related]  

  • 7. Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.
    Wacher VJ; Wu CY; Benet LZ
    Mol Carcinog; 1995 Jul; 13(3):129-34. PubMed ID: 7619215
    [No Abstract]   [Full Text] [Related]  

  • 8. Active secretion and enterocytic drug metabolism barriers to drug absorption.
    Wacher VJ; Salphati L; Benet LZ
    Adv Drug Deliv Rev; 2001 Mar; 46(1-3):89-102. PubMed ID: 11259835
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Strategies to overcome simultaneous P-glycoprotein mediated efflux and CYP3A4 mediated metabolism of drugs.
    Patel J; Mitra AK
    Pharmacogenomics; 2001 Nov; 2(4):401-15. PubMed ID: 11722289
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.
    Kim RB; Wandel C; Leake B; Cvetkovic M; Fromm MF; Dempsey PJ; Roden MM; Belas F; Chaudhary AK; Roden DM; Wood AJ; Wilkinson GR
    Pharm Res; 1999 Mar; 16(3):408-14. PubMed ID: 10213372
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Grapefruit juice activates P-glycoprotein-mediated drug transport.
    Soldner A; Christians U; Susanto M; Wacher VJ; Silverman JA; Benet LZ
    Pharm Res; 1999 Apr; 16(4):478-85. PubMed ID: 10227700
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: the role of gut CYP3A and P-glycoprotein.
    Di Marco MP; Edwards DJ; Wainer IW; Ducharme MP
    Life Sci; 2002 Jul; 71(10):1149-60. PubMed ID: 12095536
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overlapping substrate specificities of cytochrome P450 3A and P-glycoprotein for a novel cysteine protease inhibitor.
    Zhang Y; Guo X; Lin ET; Benet LZ
    Drug Metab Dispos; 1998 Apr; 26(4):360-6. PubMed ID: 9531525
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers.
    Raeissi SD; Hidalgo IJ; Segura-Aguilar J; Artursson P
    Pharm Res; 1999 May; 16(5):625-32. PubMed ID: 10350002
    [TBL] [Abstract][Full Text] [Related]  

  • 15. P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.
    Hendrikx JJ; Lagas JS; Rosing H; Schellens JH; Beijnen JH; Schinkel AH
    Int J Cancer; 2013 May; 132(10):2439-47. PubMed ID: 23090875
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery.
    Benet LZ; Izumi T; Zhang Y; Silverman JA; Wacher VJ
    J Control Release; 1999 Nov; 62(1-2):25-31. PubMed ID: 10518631
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Can oral midazolam predict oral cyclosporine disposition?
    Paine MF; Davis CL; Shen DD; Marsh CL; Raisys VA; Thummel KE
    Eur J Pharm Sci; 2000 Nov; 12(1):51-62. PubMed ID: 11121733
    [TBL] [Abstract][Full Text] [Related]  

  • 18. P-Glycoprotein in clinical cardiology.
    Rodriguez I; Abernethy DR; Woosley RL
    Circulation; 1999 Feb; 99(4):472-4. PubMed ID: 9927391
    [No Abstract]   [Full Text] [Related]  

  • 19. Intestinal metabolism promotes regional differences in apical uptake of indinavir: coupled effect of P-glycoprotein and cytochrome P450 3A on indinavir membrane permeability in rat.
    Li LY; Amidon GL; Kim JS; Heimbach T; Kesisoglou F; Topliss JT; Fleisher D
    J Pharmacol Exp Ther; 2002 May; 301(2):586-93. PubMed ID: 11961060
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans.
    Wilkinson GR
    J Pharmacokinet Biopharm; 1996 Oct; 24(5):475-90. PubMed ID: 9131486
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.