208 related articles for article (PubMed ID: 11334569)
1. Synthesis and biological evaluation of novel A-ring modified hexacyclic camptothecin analogues.
Kim DK; Ryu DH; Lee JY; Lee N; Kim YW; Kim JS; Chang K; Im GJ; Kim TK; Choi WS
J Med Chem; 2001 May; 44(10):1594-602. PubMed ID: 11334569
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and antitumor activity of ring A- and F-modified hexacyclic camptothecin analogues.
Sugimori M; Ejima A; Ohsuki S; Uoto K; Mitsui I; Kawato Y; Hirota Y; Sato K; Terasawa H
J Med Chem; 1998 Jun; 41(13):2308-18. PubMed ID: 9632364
[TBL] [Abstract][Full Text] [Related]
3. Homocamptothecins: synthesis and antitumor activity of novel E-ring-modified camptothecin analogues.
Lavergne O; Lesueur-Ginot L; Pla Rodas F; Kasprzyk PG; Pommier J; Demarquay D; Prévost G; Ulibarri G; Rolland A; Schiano-Liberatore AM; Harnett J; Pons D; Camara J; Bigg DC
J Med Chem; 1998 Dec; 41(27):5410-9. PubMed ID: 9876111
[TBL] [Abstract][Full Text] [Related]
4. Antitumor effect of DX-8951, a novel camptothecin analog, on human pancreatic tumor cells and their CPT-11-resistant variants cultured in vitro and xenografted into nude mice.
Takiguchi S; Kumazawa E; Shimazoe T; Tohgo A; Kono A
Jpn J Cancer Res; 1997 Aug; 88(8):760-9. PubMed ID: 9330608
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and antitumor activity of the hexacyclic camptothecin derivatives.
Gao H; Zhang X; Chen Y; Shen H; Pang T; Sun J; Xu C; Ding J; Li C; Lu W
Bioorg Med Chem Lett; 2005 Jul; 15(13):3233-6. PubMed ID: 15913996
[TBL] [Abstract][Full Text] [Related]
6. The novel silatecan 7-tert-butyldimethylsilyl-10-hydroxycamptothecin displays high lipophilicity, improved human blood stability, and potent anticancer activity.
Bom D; Curran DP; Kruszewski S; Zimmer SG; Thompson Strode J; Kohlhagen G; Du W; Chavan AJ; Fraley KA; Bingcang AL; Latus LJ; Pommier Y; Burke TG
J Med Chem; 2000 Oct; 43(21):3970-80. PubMed ID: 11052802
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and antitumor activity of A-ring modified hexacyclic analogues of camptothecin.
Li DZ; Wang CY; Pan XD; Liu HY; Fu ZD; Wu S
Yao Xue Xue Bao; 2005 Mar; 40(3):241-7. PubMed ID: 15952596
[TBL] [Abstract][Full Text] [Related]
8. Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties.
Lesueur-Ginot L; Demarquay D; Kiss R; Kasprzyk PG; Dassonneville L; Bailly C; Camara J; Lavergne O; Bigg DC
Cancer Res; 1999 Jun; 59(12):2939-43. PubMed ID: 10383158
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of new camptothecin analogs with improved antitumor activities.
Niizuma S; Tsukazaki M; Suda H; Murata T; Ohwada J; Ozawa S; Fukuda H; Murasaki C; Kohchi M; Morikami K; Yoshinari K; Endo M; Ura M; Tanimura H; Miyazaki Y; Takasuka T; Kawashima A; Nanba E; Nakano K; Ogawa K; Kobayashi K; Okabe H; Umeda I; Shimma N
Bioorg Med Chem Lett; 2009 Apr; 19(7):2018-21. PubMed ID: 19254843
[TBL] [Abstract][Full Text] [Related]
10. Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks.
Bailly C; Lansiaux A; Dassonneville L; Demarquay D; Coulomb H; Huchet M; Lavergne O; Bigg DC
Biochemistry; 1999 Nov; 38(47):15556-63. PubMed ID: 10569939
[TBL] [Abstract][Full Text] [Related]
11. Antitumor agents. 7. Synthesis and antitumor activity of novel hexacyclic camptothecin analogues.
Sugimori M; Ejima A; Ohsuki S; Uoto K; Mitsui I; Matsumoto K; Kawato Y; Yasuoka M; Sato K; Tagawa H
J Med Chem; 1994 Sep; 37(19):3033-9. PubMed ID: 7932525
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and evaluation of 9-benzylideneamino derivatives of homocamptothecin as potent inhibitors of DNA topoisomerase I.
Guo W; Miao Z; Sheng C; Yao J; Feng H; Zhang W; Zhu L; Liu W; Cheng P; Zhang J; Che X; Wang W; Luo C; Xu Y
Eur J Med Chem; 2010 Jun; 45(6):2223-8. PubMed ID: 20202723
[TBL] [Abstract][Full Text] [Related]
13. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo.
Mitsui I; Kumazawa E; Hirota Y; Aonuma M; Sugimori M; Ohsuki S; Uoto K; Ejima A; Terasawa H; Sato K
Jpn J Cancer Res; 1995 Aug; 86(8):776-82. PubMed ID: 7559102
[TBL] [Abstract][Full Text] [Related]
14. Homocamptothecin, an E-ring-modified camptothecin, exerts more potent antiproliferative activity than other topoisomerase I inhibitors in human colon cancers obtained from surgery and maintained in vitro under histotypical culture conditions.
Philippart P; Harper L; Chaboteaux C; Decaestecker C; Bronckart Y; Gordover L; Lesueur-Ginot L; Malonne H; Lavergne O; Bigg DC; da Costa PM; Kiss R
Clin Cancer Res; 2000 Apr; 6(4):1557-62. PubMed ID: 10778989
[TBL] [Abstract][Full Text] [Related]
15. Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity.
Dallavalle S; Ferrari A; Biasotti B; Merlini L; Penco S; Gallo G; Marzi M; Tinti MO; Martinelli R; Pisano C; Carminati P; Carenini N; Beretta G; Perego P; De Cesare M; Pratesi G; Zunino F
J Med Chem; 2001 Sep; 44(20):3264-74. PubMed ID: 11563925
[TBL] [Abstract][Full Text] [Related]
16. Novel hexacyclic camptothecin derivatives. Part 1: synthesis and cytotoxicity of camptothecins with an A-ring fused 1,3-oxazine ring.
Wang S; Li Y; Liu Y; Lu A; You Q
Bioorg Med Chem Lett; 2008 Jul; 18(14):4095-7. PubMed ID: 18554906
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of new homocamptothecin analogs.
Luo Y; Yu S; Tong L; Huang Q; Lu W; Chen Y
Eur J Med Chem; 2012 Aug; 54():281-6. PubMed ID: 22647222
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of novel 7-acyl homocamptothecins as Topoisomerase I inhibitors.
Liu W; Zhu L; Guo W; Zhuang C; Zhang Y; Sheng C; Cheng P; Yao J; Wang W; Dong G; Wang S; Miao Z; Zhang W
Eur J Med Chem; 2011 Jun; 46(6):2408-14. PubMed ID: 21463912
[TBL] [Abstract][Full Text] [Related]
19. Novel 7-substituted camptothecins with potent antitumor activity.
Dallavalle S; Delsoldato T; Ferrari A; Merlini L; Penco S; Carenini N; Perego P; De Cesare M; Pratesi G; Zunino F
J Med Chem; 2000 Oct; 43(21):3963-9. PubMed ID: 11052801
[TBL] [Abstract][Full Text] [Related]
20. DX-8951f, a water-soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN-38-resistant variant.
Joto N; Ishii M; Minami M; Kuga H; Mitsui I; Tohgo A
Int J Cancer; 1997 Aug; 72(4):680-6. PubMed ID: 9259410
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
