BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

458 related articles for article (PubMed ID: 11336976)

  • 21. Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor.
    Ripp SL; Fitzpatrick JL; Peters JM; Prough RA
    Drug Metab Dispos; 2002 May; 30(5):570-5. PubMed ID: 11950789
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Expression of PXR, CYP3A and MDR1 genes in liver of zebrafish.
    Bresolin T; de Freitas Rebelo M; Celso Dias Bainy A
    Comp Biochem Physiol C Toxicol Pharmacol; 2005; 140(3-4):403-7. PubMed ID: 15914091
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors.
    Pascussi JM; Gerbal-Chaloin S; Drocourt L; Maurel P; Vilarem MJ
    Biochim Biophys Acta; 2003 Feb; 1619(3):243-53. PubMed ID: 12573484
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
    Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
    Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Rabbit pregnane X receptor is activated by rifampicin.
    Savas U; Wester MR; Griffin KJ; Johnson EF
    Drug Metab Dispos; 2000 May; 28(5):529-37. PubMed ID: 10772631
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Rat PXR reporter-gene activity correlates with the induction of CYP3A in rat precision-cut liver slices.
    Cui X; Thomas A; Montgomery D; Gu C; Morrison RA; White RE; Cheng KC
    Comb Chem High Throughput Screen; 2005 Jun; 8(4):341-6. PubMed ID: 16101010
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Regulation of cyp3a gene transcription by the pregnane x receptor.
    Goodwin B; Redinbo MR; Kliewer SA
    Annu Rev Pharmacol Toxicol; 2002; 42():1-23. PubMed ID: 11807162
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity.
    Staudinger JL; Goodwin B; Jones SA; Hawkins-Brown D; MacKenzie KI; LaTour A; Liu Y; Klaassen CD; Brown KK; Reinhard J; Willson TM; Koller BH; Kliewer SA
    Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3369-74. PubMed ID: 11248085
    [TBL] [Abstract][Full Text] [Related]  

  • 30. CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.
    Tippin TK; Hamilton G; Moore L; Beaudet EJ; Jolley S; Brodie TA; Andrews RC; Becherer JD; McDougald DL; Gaul MD; Hoivik DJ; Mellon-Kusibab K; Lehmann J; Kliewer S; Novick S; Laethem R; Zhao Z; LeCluyse EL
    Drug Metab Dispos; 2003 Jul; 31(7):870-7. PubMed ID: 12814963
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Postnatal expression and induction by pregnenolone-16alpha-carbonitrile of the organic anion-transporting polypeptide 2 in rat liver.
    Guo GL; Johnson DR; Klaassen CD
    Drug Metab Dispos; 2002 Mar; 30(3):283-8. PubMed ID: 11854146
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
    Wang H; Faucette SR; Gilbert D; Jolley SL; Sueyoshi T; Negishi M; LeCluyse EL
    Drug Metab Dispos; 2003 May; 31(5):620-30. PubMed ID: 12695351
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
    Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Relative receptor expression is a determinant in xenobiotic-mediated CYP3A induction in rat and human cells.
    Swales K; Plant N; Ayrton A; Hood S; Gibson G
    Xenobiotica; 2003 Jul; 33(7):703-16. PubMed ID: 12893520
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
    Xu DX; Wei W; Sun MF; Wu CY; Wang JP; Wei LZ; Zhou CF
    Free Radic Biol Med; 2004 Jul; 37(1):10-22. PubMed ID: 15183191
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element.
    El-Sankary W; Bombail V; Gibson GG; Plant N
    Drug Metab Dispos; 2002 Sep; 30(9):1029-34. PubMed ID: 12167569
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Lipopolysaccharide and cecal ligation/puncture differentially affect the subcellular distribution of the pregnane X receptor but consistently cause suppression of its target genes CYP3A.
    Sachdeva K; Yan B; Chichester CO
    Shock; 2003 May; 19(5):469-74. PubMed ID: 12744492
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element.
    Schuetz EG; Brimer C; Schuetz JD
    Mol Pharmacol; 1998 Dec; 54(6):1113-7. PubMed ID: 9855641
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver.
    Squires EJ; Sueyoshi T; Negishi M
    J Biol Chem; 2004 Nov; 279(47):49307-14. PubMed ID: 15347657
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
    Sahi J; Shord SS; Lindley C; Ferguson S; LeCluyse EL
    J Biochem Mol Toxicol; 2009; 23(1):43-58. PubMed ID: 19202563
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 23.