BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 11344272)

  • 1. Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway.
    Cho KS; Lee JH; Kim S; Kim D; Koh H; Lee J; Kim C; Kim J; Chung J
    Proc Natl Acad Sci U S A; 2001 May; 98(11):6144-9. PubMed ID: 11344272
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival.
    Flynn P; Wongdagger M; Zavar M; Dean NM; Stokoe D
    Curr Biol; 2000 Nov; 10(22):1439-42. PubMed ID: 11102805
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Protein kinase B and its role in the signal transduction pathway mediated by phosphoinositide 3-kinase].
    Zou W; Li ZY; Li CL; Cui ZC
    Sheng Li Ke Xue Jin Zhan; 2000 Apr; 31(2):120-4. PubMed ID: 12545728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B.
    Anderson KE; Coadwell J; Stephens LR; Hawkins PT
    Curr Biol; 1998 Jun; 8(12):684-91. PubMed ID: 9637919
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.
    Kim S; Jee K; Kim D; Koh H; Chung J
    J Biol Chem; 2001 Apr; 276(16):12864-70. PubMed ID: 11278269
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.
    Blalock WL; Navolanic PM; Steelman LS; Shelton JG; Moye PW; Lee JT; Franklin RA; Mirza A; McMahon M; White MK; McCubrey JA
    Leukemia; 2003 Jun; 17(6):1058-67. PubMed ID: 12764369
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
    Rodríguez-Escudero I; Roelants FM; Thorner J; Nombela C; Molina M; Cid VJ
    Biochem J; 2005 Sep; 390(Pt 2):613-23. PubMed ID: 15913452
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
    Sekulić A; Hudson CC; Homme JL; Yin P; Otterness DM; Karnitz LM; Abraham RT
    Cancer Res; 2000 Jul; 60(13):3504-13. PubMed ID: 10910062
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IGF-I elicits growth of human intestinal smooth muscle cells by activation of PI3K, PDK-1, and p70S6 kinase.
    Kuemmerle JF
    Am J Physiol Gastrointest Liver Physiol; 2003 Mar; 284(3):G411-22. PubMed ID: 12444011
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of PTEN expression does not contribute to PDK-1 activity and PKC activation-loop phosphorylation in Jurkat leukaemic T cells.
    Freeley M; Park J; Yang KJ; Wange RL; Volkov Y; Kelleher D; Long A
    Cell Signal; 2007 Dec; 19(12):2444-57. PubMed ID: 17826953
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ganglioside loss promotes survival primarily by activating integrin-linked kinase/Akt without phosphoinositide 3-OH kinase signaling.
    Sun P; Wang XQ; Lopatka K; Bangash S; Paller AS
    J Invest Dermatol; 2002 Jul; 119(1):107-17. PubMed ID: 12164932
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
    Chandrasekher G; Sailaja D
    Invest Ophthalmol Vis Sci; 2004 Oct; 45(10):3577-88. PubMed ID: 15452065
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.
    Verdu J; Buratovich MA; Wilder EL; Birnbaum MJ
    Nat Cell Biol; 1999 Dec; 1(8):500-6. PubMed ID: 10587646
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways.
    Gao X; Neufeld TP; Pan D
    Dev Biol; 2000 May; 221(2):404-18. PubMed ID: 10790335
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Follicle-Stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-lnduced kinase (Sgk): evidence for A kinase-independent signaling by FSH in granulosa cells.
    Gonzalez-Robayna IJ; Falender AE; Ochsner S; Firestone GL; Richards JS
    Mol Endocrinol; 2000 Aug; 14(8):1283-300. PubMed ID: 10935551
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of akt/protein kinase B signaling by naltrindole in small cell lung cancer cells.
    Chen YL; Law PY; Loh HH
    Cancer Res; 2004 Dec; 64(23):8723-30. PubMed ID: 15574783
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans.
    Paradis S; Ailion M; Toker A; Thomas JH; Ruvkun G
    Genes Dev; 1999 Jun; 13(11):1438-52. PubMed ID: 10364160
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The PI3K-PDK1 connection: more than just a road to PKB.
    Vanhaesebroeck B; Alessi DR
    Biochem J; 2000 Mar; 346 Pt 3(Pt 3):561-76. PubMed ID: 10698680
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PDK1 regulates growth through Akt and S6K in Drosophila.
    Rintelen F; Stocker H; Thomas G; Hafen E
    Proc Natl Acad Sci U S A; 2001 Dec; 98(26):15020-5. PubMed ID: 11752451
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PI3K-Akt pathway: its functions and alterations in human cancer.
    Osaki M; Oshimura M; Ito H
    Apoptosis; 2004 Nov; 9(6):667-76. PubMed ID: 15505410
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.