BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 11349123)

  • 1. Cytokine-independent Jak3 activation upon T cell receptor (TCR) stimulation through direct association of Jak3 and the TCR complex.
    Tomita K; Saijo K; Yamasaki S; Iida T; Nakatsu F; Arase H; Ohno H; Shirasawa T; Kuriyama T; O'Shea JJ; Saito T
    J Biol Chem; 2001 Jul; 276(27):25378-85. PubMed ID: 11349123
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rapid tyrosine phosphorylation of Lck following ligation of the tumor-associated cell surface molecule A6H.
    Labuda T; Gerwien J; Odum N; Dohlsten M
    Int Immunol; 1999 Mar; 11(3):427-33. PubMed ID: 10221654
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential Src family kinase activity requirements for CD3 zeta phosphorylation/ZAP70 recruitment and CD3 epsilon phosphorylation.
    Lysechko TL; Ostergaard HL
    J Immunol; 2005 Jun; 174(12):7807-14. PubMed ID: 15944285
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Age-related impairments in TCR/CD3 activation of ZAP-70 are associated with reduced tyrosine phosphorylations of zeta-chains and p59fyn/p56lck in human T cells.
    Whisler RL; Chen M; Liu B; Newhouse YG
    Mech Ageing Dev; 1999 Nov; 111(1):49-66. PubMed ID: 10576607
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tumor-induced suppression of T lymphocyte proliferation coincides with inhibition of Jak3 expression and IL-2 receptor signaling: role of soluble products from human renal cell carcinomas.
    Kolenko V; Wang Q; Riedy MC; O'Shea J; Ritz J; Cathcart MK; Rayman P; Tubbs R; Edinger M; Novick A; Bukowski R; Finke J
    J Immunol; 1997 Sep; 159(6):3057-67. PubMed ID: 9300731
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases.
    Guntermann C; Alexander DR
    J Immunol; 2002 May; 168(9):4420-9. PubMed ID: 11970985
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.
    Yamasaki S; Nishida K; Hibi M; Sakuma M; Shiina R; Takeuchi A; Ohnishi H; Hirano T; Saito T
    J Biol Chem; 2001 Nov; 276(48):45175-83. PubMed ID: 11572860
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc.
    Walk SF; March ME; Ravichandran KS
    Eur J Immunol; 1998 Aug; 28(8):2265-75. PubMed ID: 9710204
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling.
    Denny MF; Kaufman HC; Chan AC; Straus DB
    J Biol Chem; 1999 Feb; 274(8):5146-52. PubMed ID: 9988764
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Age-related impairment of p56lck and ZAP-70 activities in human T lymphocytes activated through the TcR/CD3 complex.
    Fülöp T; Gagné D; Goulet AC; Desgeorges S; Lacombe G; Arcand M; Dupuis G
    Exp Gerontol; 1999 Apr; 34(2):197-216. PubMed ID: 10363787
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rosmarinic acid inhibits TCR-induced T cell activation and proliferation in an Lck-dependent manner.
    Won J; Hur YG; Hur EM; Park SH; Kang MA; Choi Y; Park C; Lee KH; Yun Y
    Eur J Immunol; 2003 Apr; 33(4):870-9. PubMed ID: 12672052
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation.
    Zhou YJ; Magnuson KS; Cheng TP; Gadina M; Frucht DM; Galon J; Candotti F; Geahlen RL; Changelian PS; O'Shea JJ
    Mol Cell Biol; 2000 Jun; 20(12):4371-80. PubMed ID: 10825200
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deficient expression of p56(lck) in Th2 cells leads to partial TCR signaling and a dysregulation in lymphokine mRNA levels.
    al-Ramadi BK; Nakamura T; Leitenberg D; Bothwell AL
    J Immunol; 1996 Dec; 157(11):4751-61. PubMed ID: 8943376
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential association of protein tyrosine kinases with the T cell receptor is linked to the induction of anergy and its prevention by B7 family-mediated costimulation.
    Boussiotis VA; Barber DL; Lee BJ; Gribben JG; Freeman GJ; Nadler LM
    J Exp Med; 1996 Aug; 184(2):365-76. PubMed ID: 8760790
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.
    Williams BL; Irvin BJ; Sutor SL; Chini CC; Yacyshyn E; Bubeck Wardenburg J; Dalton M; Chan AC; Abraham RT
    EMBO J; 1999 Apr; 18(7):1832-44. PubMed ID: 10202147
    [TBL] [Abstract][Full Text] [Related]  

  • 16. T cell-specific adapter protein inhibits T cell activation by modulating Lck activity.
    Sundvold V; Torgersen KM; Post NH; Marti F; King PD; Røttingen JA; Spurkland A; Lea T
    J Immunol; 2000 Sep; 165(6):2927-31. PubMed ID: 10975797
    [TBL] [Abstract][Full Text] [Related]  

  • 17. T cells from Jak3-deficient mice have intact TCR signaling, but increased apoptosis.
    Thomis DC; Lee W; Berg LJ
    J Immunol; 1997 Nov; 159(10):4708-19. PubMed ID: 9366394
    [TBL] [Abstract][Full Text] [Related]  

  • 18. T cells infiltrating non-Hodgkin's B cell lymphomas show altered tyrosine phosphorylation pattern even though T cell receptor/CD3-associated kinases are present.
    Wang Q; Stanley J; Kudoh S; Myles J; Kolenko V; Yi T; Tubbs R; Bukowski R; Finke J
    J Immunol; 1995 Aug; 155(3):1382-92. PubMed ID: 7636203
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Suppression of early T-cell-receptor-triggered cellular activation by the Janus kinase 3 inhibitor WHI-P-154.
    Säemann MD; Zeyda M; Diakos C; Szekeres A; Böhmig GA; Kelemen P; Parolini O; Stockinger H; Prieschl EE; Stulnig TM; Baumruker T; Zlabinger GJ
    Transplantation; 2003 Jun; 75(11):1864-72. PubMed ID: 12811247
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling.
    Chae HD; Siefring JE; Hildeman DA; Gu Y; Williams DA
    PLoS One; 2010 Nov; 5(11):e13970. PubMed ID: 21103055
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.