BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

87 related articles for article (PubMed ID: 11352471)

  • 1. The Oxyanion Hole in Serine beta-Lactamase Catalysis: Interactions of Thiono Substrates with the Active Site.
    Curley K; Pratt RF
    Bioorg Chem; 2000 Dec; 28(6):338-56. PubMed ID: 11352471
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of an acylation transition-state analog of the TEM-1 beta-lactamase. Mechanistic implications for class A beta-lactamases.
    Maveyraud L; Pratt RF; Samama JP
    Biochemistry; 1998 Feb; 37(8):2622-8. PubMed ID: 9485412
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanisms of antibiotic resistance: QM/MM modeling of the acylation reaction of a class A beta-lactamase with benzylpenicillin.
    Hermann JC; Hensen C; Ridder L; Mulholland AJ; Höltje HD
    J Am Chem Soc; 2005 Mar; 127(12):4454-65. PubMed ID: 15783228
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kinetics and mechanism of the hydrolysis of depsipeptides catalyzed by the beta-lactamase of Enterobacter cloacae P99.
    Xu Y; Soto G; Hirsch KR; Pratt RF
    Biochemistry; 1996 Mar; 35(11):3595-603. PubMed ID: 8639511
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The D-methyl group in beta-lactamase evolution: evidence from the Y221G and GC1 mutants of the class C beta-lactamase of Enterobacter cloacae P99.
    Adediran SA; Zhang Z; Nukaga M; Palzkill T; Pratt RF
    Biochemistry; 2005 May; 44(20):7543-52. PubMed ID: 15895997
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Different transition-state structures for the reactions of beta-lactams and analogous beta-sultams with serine beta-lactamases.
    Tsang WY; Ahmed N; Hinchliffe PS; Wood JM; Harding LP; Laws AP; Page MI
    J Am Chem Soc; 2005 Dec; 127(49):17556-64. PubMed ID: 16332108
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of class D beta-lactamases by diaroyl phosphates.
    Majumdar S; Adediran SA; Nukaga M; Pratt RF
    Biochemistry; 2005 Dec; 44(49):16121-9. PubMed ID: 16331972
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kinetics of turnover of cefotaxime by the Enterobacter cloacae P99 and GCl beta-lactamases: two free enzyme forms of the P99 beta-lactamase detected by a combination of pre- and post-steady state kinetics.
    Kumar S; Adediran SA; Nukaga M; Pratt RF
    Biochemistry; 2004 Mar; 43(9):2664-72. PubMed ID: 14992604
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thermodynamic evaluation of a covalently bonded transition state analogue inhibitor: inhibition of beta-lactamases by phosphonates.
    Nagarajan R; Pratt RF
    Biochemistry; 2004 Aug; 43(30):9664-73. PubMed ID: 15274621
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 13C- and 1H-NMR studies of oxyanion and tetrahedral intermediate stabilization by the serine proteinases: optimizing inhibitor warhead specificity and potency by studying the inhibition of the serine proteinases by peptide-derived chloromethane and glyoxal inhibitors.
    Malthouse JP
    Biochem Soc Trans; 2007 Jun; 35(Pt 3):566-70. PubMed ID: 17511653
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transition-state stabilization at the oxyanion binding sites of serine and thiol proteinases: hydrolyses of thiono and oxygen esters.
    Asbóth B; Polgár L
    Biochemistry; 1983 Jan; 22(1):117-22. PubMed ID: 6338911
    [TBL] [Abstract][Full Text] [Related]  

  • 12. pKa, MM, and QM studies of mechanisms of beta-lactamases and penicillin-binding proteins: acylation step.
    Massova I; Kollman PA
    J Comput Chem; 2002 Dec; 23(16):1559-76. PubMed ID: 12395425
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The thiolase reaction mechanism: the importance of Asn316 and His348 for stabilizing the enolate intermediate of the Claisen condensation.
    Meriläinen G; Poikela V; Kursula P; Wierenga RK
    Biochemistry; 2009 Nov; 48(46):11011-25. PubMed ID: 19842716
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N-(phenylacetyl)glycyl-D-aziridine-2-carboxylate, an acyclic amide substrate of beta-lactamases: importance of the shape of the substrate in beta-lactamase evolution.
    Murphy BP; Pratt RF
    Biochemistry; 1991 Apr; 30(15):3640-9. PubMed ID: 2015222
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Theoretical perspectives on the reaction mechanism of serine proteases: the reaction free energy profiles of the acylation process.
    Ishida T; Kato S
    J Am Chem Soc; 2003 Oct; 125(39):12035-48. PubMed ID: 14505425
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A theoretical study on the substrate deacylation mechanism of class C beta-lactamase.
    Hata M; Tanaka Y; Fujii Y; Neya S; Hoshino T
    J Phys Chem B; 2005 Aug; 109(33):16153-60. PubMed ID: 16853052
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant.
    Sun T; Bethel CR; Bonomo RA; Knox JR
    Biochemistry; 2004 Nov; 43(44):14111-7. PubMed ID: 15518561
    [TBL] [Abstract][Full Text] [Related]  

  • 18. X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate.
    Wilmouth RC; Edman K; Neutze R; Wright PA; Clifton IJ; Schneider TR; Schofield CJ; Hajdu J
    Nat Struct Biol; 2001 Aug; 8(8):689-94. PubMed ID: 11473259
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A dynamic structure for the acyl-enzyme species of the antibiotic aztreonam with the Citrobacter freundii beta-lactamase revealed by infrared spectroscopy and molecular dynamics simulations.
    Wilkinson AS; Bryant PK; Meroueh SO; Page MG; Mobashery S; Wharton CW
    Biochemistry; 2003 Feb; 42(7):1950-7. PubMed ID: 12590581
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Details of the acyl-enzyme intermediate and the oxyanion hole in serine protease catalysis.
    Whiting AK; Peticolas WL
    Biochemistry; 1994 Jan; 33(2):552-61. PubMed ID: 8286385
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.