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6. RPR 130401, a nonpeptidomimetic farnesyltransferase inhibitor with in vivo activity. Vrignaud P; Bissery MC; Mailliet P; Lavelle F Ann N Y Acad Sci; 1999; 886():249-51. PubMed ID: 10667231 [No Abstract] [Full Text] [Related]
7. 3,8-Diazabicyclo[3.2.1]octan-2-one peptide mimetics: synthesis of a conformationally restricted inhibitor of farnesyltransferase. Dinsmore CJ; Bergman JM; Bogusky MJ; Culberson JC; Hamilton KA; Graham SL Org Lett; 2001 Mar; 3(6):865-8. PubMed ID: 11263902 [TBL] [Abstract][Full Text] [Related]
8. Novel and selective imidazole-containing biphenyl inhibitors of protein farnesyltransferase. Curtin ML; Florjancic AS; Cohen J; Gu WZ; Frost DJ; Muchmore SW; Sham HL Bioorg Med Chem Lett; 2003 Apr; 13(7):1367-71. PubMed ID: 12657284 [TBL] [Abstract][Full Text] [Related]
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11. Conformational restriction of flexible ligands guided by the transferred noe experiment: potent macrocyclic inhibitors of farnesyltransferase. Dinsmore CJ; Bogusky MJ; Culberson JC; Bergman JM; Homnick CF; Zartman CB; Mosser SD; Schaber MD; Robinson RG; Koblan KS; Huber HE; Graham SL; Hartman GD; Huff JR; Williams TM J Am Chem Soc; 2001 Mar; 123(9):2107-8. PubMed ID: 11456854 [No Abstract] [Full Text] [Related]
12. Development of tripeptidyl farnesyltransferase inhibitors. Lee HY; Sohn JH; Kwon BM Bioorg Med Chem Lett; 2002 Jun; 12(12):1599-602. PubMed ID: 12039571 [TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, and activity of achiral analogs of 2-quinolones and indoles as non-thiol farnesyltransferase inhibitors. Li Q; Woods KW; Wang W; Lin NH; Claiborne A; Gu WZ; Cohen J; Stoll VS; Hutchins C; Frost D; Rosenberg SH; Sham HL Bioorg Med Chem Lett; 2005 Apr; 15(8):2033-9. PubMed ID: 15808463 [TBL] [Abstract][Full Text] [Related]
14. Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency. Gwaltney SL; O'Connor SJ; Nelson LT; Sullivan GM; Imade H; Wang W; Hasvold L; Li Q; Cohen J; Gu WZ; Tahir SK; Bauch J; Marsh K; Ng SC; Frost DJ; Zhang H; Muchmore S; Jakob CG; Stoll V; Hutchins C; Rosenberg SH; Sham HL Bioorg Med Chem Lett; 2003 Apr; 13(7):1363-6. PubMed ID: 12657283 [TBL] [Abstract][Full Text] [Related]
15. Benzimidazolones and indoles as non-thiol farnesyltransferase inhibitors based on tipifarnib scaffold: synthesis and activity. Li Q; Li T; Woods KW; Gu WZ; Cohen J; Stoll VS; Galicia T; Hutchins C; Frost D; Rosenberg SH; Sham HL Bioorg Med Chem Lett; 2005 Jun; 15(11):2918-22. PubMed ID: 15911281 [TBL] [Abstract][Full Text] [Related]
16. Cellular effects of a new farnesyltransferase inhibitor, RPR-115135, in a human isogenic colon cancer cell line model system HCT-116. Russo P; Ottoboni C; Falugi C; Reinhold W; Riou JF; Parodi S; O'Connor PM Ann N Y Acad Sci; 1999; 886():252-6. PubMed ID: 10667232 [No Abstract] [Full Text] [Related]
17. Kurasoins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. II. Structure elucidation and total synthesis. Uchida R; Shiomi K; Sunazuka T; Inokoshi J; Nishizawa A; Hirose T; Tanaka H; Iwai Y; Omura S J Antibiot (Tokyo); 1996 Sep; 49(9):886-9. PubMed ID: 8931722 [TBL] [Abstract][Full Text] [Related]
18. Discovery and structure-activity relationships of novel piperidine inhibitors of farnesyltransferase. Nara S; Tanaka R; Eishima J; Hara M; Takahashi Y; Otaki S; Foglesong RJ; Hughes PF; Turkington S; Kanda Y J Med Chem; 2003 Jun; 46(12):2467-73. PubMed ID: 12773050 [TBL] [Abstract][Full Text] [Related]
19. Non-thiol farnesyltransferase inhibitors: the concept of benzophenone-based bisubstrate analogue farnesyltransferase inhibitors. Schlitzer M; Sattler I Eur J Med Chem; 2000; 35(7-8):721-6. PubMed ID: 10960188 [TBL] [Abstract][Full Text] [Related]
20. [Inhibitors of farnesyltransferase: a new approach for development of potential cancer drugs]. Schlitzer M Pharm Unserer Zeit; 1998 Nov; 27(6):278-88. PubMed ID: 9894422 [No Abstract] [Full Text] [Related] [Next] [New Search]