These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

100 related articles for article (PubMed ID: 11375000)

  • 1. Synthesis of oxa-bridged analogues of farnesyltransferase inhibitor RPR 115135.
    Martin C; Mailliet P; Maddaluno J
    J Org Chem; 2001 Jun; 66(11):3797-805. PubMed ID: 11375000
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Diastereoselective syntheses of new analogues of the farnesyltransferase inhibitor RPR 130401.
    Pichon N; Harrison-Marchand A; Mailliet P; Maddaluno J
    J Org Chem; 2004 Oct; 69(21):7220-7. PubMed ID: 15471472
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of conformationally constrained 5,6,7, 8-Tetrahydroimidazo[1,5-a]pyridine inhibitors of farnesyltransferase.
    Dinsmore CJ; Zartman CB; Baginsky WF; O'Neill TJ; Koblan KS; Chen IW; McLoughlin DA; Olah TV; Huff JR
    Org Lett; 2000 Nov; 2(22):3473-6. PubMed ID: 11082012
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A diastereoselective switch in the access to isobenzofuran-derived alpha-selenoesters.
    Martin C; Mailliet P; Maddaluno J
    Org Lett; 2000 Apr; 2(7):923-5. PubMed ID: 10768187
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Non-thiol farnesyltransferase inhibitors: N-(4-acylamino-3-benzoylphenyl)-3-[5-(4-nitrophenyl)-2-furyl]acrylic acid amides.
    Kettler K; Sakowski J; Silber K; Sattler I; Klebe G; Schlitzer M
    Bioorg Med Chem; 2003 Apr; 11(7):1521-30. PubMed ID: 12705292
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RPR 130401, a nonpeptidomimetic farnesyltransferase inhibitor with in vivo activity.
    Vrignaud P; Bissery MC; Mailliet P; Lavelle F
    Ann N Y Acad Sci; 1999; 886():249-51. PubMed ID: 10667231
    [No Abstract]   [Full Text] [Related]  

  • 7. 3,8-Diazabicyclo[3.2.1]octan-2-one peptide mimetics: synthesis of a conformationally restricted inhibitor of farnesyltransferase.
    Dinsmore CJ; Bergman JM; Bogusky MJ; Culberson JC; Hamilton KA; Graham SL
    Org Lett; 2001 Mar; 3(6):865-8. PubMed ID: 11263902
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel and selective imidazole-containing biphenyl inhibitors of protein farnesyltransferase.
    Curtin ML; Florjancic AS; Cohen J; Gu WZ; Frost DJ; Muchmore SW; Sham HL
    Bioorg Med Chem Lett; 2003 Apr; 13(7):1367-71. PubMed ID: 12657284
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of 4-[(3-methyl-3H-imidazol-4-yl)-(2-phenylethynyl-benzyloxy)-methyl]-benzonitrile as novel farnesyltransferase inhibitor.
    Lin NH; Wang L; Cohen J; Gu WZ; Frost D; Zhang H; Rosenberg S; Sham H
    Bioorg Med Chem Lett; 2003 Nov; 13(21):3821-5. PubMed ID: 14552788
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel lead structures for antimalarial farnesyltransferase inhibitors.
    Kettler K; Sakowski J; Wiesner J; Ortmann R; Jomaa H; Schlitzer M
    Pharmazie; 2005 May; 60(5):323-7. PubMed ID: 15918578
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conformational restriction of flexible ligands guided by the transferred noe experiment: potent macrocyclic inhibitors of farnesyltransferase.
    Dinsmore CJ; Bogusky MJ; Culberson JC; Bergman JM; Homnick CF; Zartman CB; Mosser SD; Schaber MD; Robinson RG; Koblan KS; Huber HE; Graham SL; Hartman GD; Huff JR; Williams TM
    J Am Chem Soc; 2001 Mar; 123(9):2107-8. PubMed ID: 11456854
    [No Abstract]   [Full Text] [Related]  

  • 12. Development of tripeptidyl farnesyltransferase inhibitors.
    Lee HY; Sohn JH; Kwon BM
    Bioorg Med Chem Lett; 2002 Jun; 12(12):1599-602. PubMed ID: 12039571
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and activity of achiral analogs of 2-quinolones and indoles as non-thiol farnesyltransferase inhibitors.
    Li Q; Woods KW; Wang W; Lin NH; Claiborne A; Gu WZ; Cohen J; Stoll VS; Hutchins C; Frost D; Rosenberg SH; Sham HL
    Bioorg Med Chem Lett; 2005 Apr; 15(8):2033-9. PubMed ID: 15808463
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency.
    Gwaltney SL; O'Connor SJ; Nelson LT; Sullivan GM; Imade H; Wang W; Hasvold L; Li Q; Cohen J; Gu WZ; Tahir SK; Bauch J; Marsh K; Ng SC; Frost DJ; Zhang H; Muchmore S; Jakob CG; Stoll V; Hutchins C; Rosenberg SH; Sham HL
    Bioorg Med Chem Lett; 2003 Apr; 13(7):1363-6. PubMed ID: 12657283
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Benzimidazolones and indoles as non-thiol farnesyltransferase inhibitors based on tipifarnib scaffold: synthesis and activity.
    Li Q; Li T; Woods KW; Gu WZ; Cohen J; Stoll VS; Galicia T; Hutchins C; Frost D; Rosenberg SH; Sham HL
    Bioorg Med Chem Lett; 2005 Jun; 15(11):2918-22. PubMed ID: 15911281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cellular effects of a new farnesyltransferase inhibitor, RPR-115135, in a human isogenic colon cancer cell line model system HCT-116.
    Russo P; Ottoboni C; Falugi C; Reinhold W; Riou JF; Parodi S; O'Connor PM
    Ann N Y Acad Sci; 1999; 886():252-6. PubMed ID: 10667232
    [No Abstract]   [Full Text] [Related]  

  • 17. Kurasoins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. II. Structure elucidation and total synthesis.
    Uchida R; Shiomi K; Sunazuka T; Inokoshi J; Nishizawa A; Hirose T; Tanaka H; Iwai Y; Omura S
    J Antibiot (Tokyo); 1996 Sep; 49(9):886-9. PubMed ID: 8931722
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery and structure-activity relationships of novel piperidine inhibitors of farnesyltransferase.
    Nara S; Tanaka R; Eishima J; Hara M; Takahashi Y; Otaki S; Foglesong RJ; Hughes PF; Turkington S; Kanda Y
    J Med Chem; 2003 Jun; 46(12):2467-73. PubMed ID: 12773050
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Non-thiol farnesyltransferase inhibitors: the concept of benzophenone-based bisubstrate analogue farnesyltransferase inhibitors.
    Schlitzer M; Sattler I
    Eur J Med Chem; 2000; 35(7-8):721-6. PubMed ID: 10960188
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Inhibitors of farnesyltransferase: a new approach for development of potential cancer drugs].
    Schlitzer M
    Pharm Unserer Zeit; 1998 Nov; 27(6):278-88. PubMed ID: 9894422
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 5.