250 related articles for article (PubMed ID: 11377375)
1. Azole-antifungal binding to a novel cytochrome P450 from Mycobacterium tuberculosis: implications for treatment of tuberculosis.
Guardiola-Diaz HM; Foster LA; Mushrush D; Vaz AD
Biochem Pharmacol; 2001 Jun; 61(12):1463-70. PubMed ID: 11377375
[TBL] [Abstract][Full Text] [Related]
2. Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes.
McLean KJ; Marshall KR; Richmond A; Hunter IS; Fowler K; Kieser T; Gurcha SS; Besra GS; Munro AW
Microbiology (Reading); 2002 Oct; 148(Pt 10):2937-2949. PubMed ID: 12368427
[TBL] [Abstract][Full Text] [Related]
3. Conservation and cloning of CYP51: a sterol 14 alpha-demethylase from Mycobacterium smegmatis.
Jackson CJ; Lamb DC; Marczylo TH; Parker JE; Manning NL; Kelly DE; Kelly SL
Biochem Biophys Res Commun; 2003 Feb; 301(2):558-63. PubMed ID: 12565899
[TBL] [Abstract][Full Text] [Related]
4. Optimized expression and catalytic properties of a wheat obtusifoliol 14alpha-demethylase (CYP51) expressed in yeast. Complementation of erg11Delta yeast mutants by plant CYP51.
Cabello-Hurtado F; Taton M; Forthoffer N; Kahn R; Bak S; Rahier A; Werck-Reichhart D
Eur J Biochem; 1999 Jun; 262(2):435-46. PubMed ID: 10336628
[TBL] [Abstract][Full Text] [Related]
5. Structural diversities of active site in clinical azole-bound forms between sterol 14alpha-demethylases (CYP51s) from human and Mycobacterium tuberculosis.
Matsuura K; Yoshioka S; Tosha T; Hori H; Ishimori K; Kitagawa T; Morishima I; Kagawa N; Waterman MR
J Biol Chem; 2005 Mar; 280(10):9088-96. PubMed ID: 15611056
[TBL] [Abstract][Full Text] [Related]
6. Bactericidal and inhibitory effects of azole antifungal compounds on Mycobacterium smegmatis.
Jackson CJ; Lamb DC; Kelly DE; Kelly SL
FEMS Microbiol Lett; 2000 Nov; 192(2):159-62. PubMed ID: 11064188
[TBL] [Abstract][Full Text] [Related]
7. Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis.
Bellamine A; Mangla AT; Nes WD; Waterman MR
Proc Natl Acad Sci U S A; 1999 Aug; 96(16):8937-42. PubMed ID: 10430874
[TBL] [Abstract][Full Text] [Related]
8. Effects of Y132H and F145L substitutions on the activity, azole resistance and spectral properties of Candida albicans sterol 14-demethylase P450 (CYP51): a live example showing the selection of altered P450 through interaction with environmental compounds.
Kudo M; Ohi M; Aoyama Y; Nitahara Y; Chung SK; Yoshida Y
J Biochem; 2005 May; 137(5):625-32. PubMed ID: 15944416
[TBL] [Abstract][Full Text] [Related]
9. Molecular design of two sterol 14alpha-demethylase homology models and their interactions with the azole antifungals ketoconazole and bifonazole.
Rupp B; Raub S; Marian C; Höltje HD
J Comput Aided Mol Des; 2005 Mar; 19(3):149-63. PubMed ID: 16059669
[TBL] [Abstract][Full Text] [Related]
10. An old activity in the cytochrome P450 superfamily (CYP51) and a new story of drugs and resistance.
Kelly SL; Lamb DC; Cannieux M; Greetham D; Jackson CJ; Marczylo T; Ugochukwu C; Kelly DE
Biochem Soc Trans; 2001 May; 29(Pt 2):122-8. PubMed ID: 11356139
[TBL] [Abstract][Full Text] [Related]
11. Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors.
Podust LM; Poulos TL; Waterman MR
Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3068-73. PubMed ID: 11248033
[TBL] [Abstract][Full Text] [Related]
12. Cloning and characterization of CYP51 from Mycobacterium avium.
Pietila MP; Vohra PK; Sanyal B; Wengenack NL; Raghavakaimal S; Thomas CF
Am J Respir Cell Mol Biol; 2006 Aug; 35(2):236-42. PubMed ID: 16543605
[TBL] [Abstract][Full Text] [Related]
13. [Expression of the Mycobacterium tuberculosis cytochrome CYP51 gene in Escherichia coli].
Shavkunov AS; Lazarev VN; Zgoda VG; Govorun VM; Levi P; Janssen P; Archakov AI
Biomed Khim; 2003; 49(2):145-52. PubMed ID: 14565078
[TBL] [Abstract][Full Text] [Related]
14. MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51.
Zanno A; Kwiatkowski N; Vaz AD; Guardiola-Diaz HM
Biochim Biophys Acta; 2005; 1707(2-3):157-69. PubMed ID: 15863094
[TBL] [Abstract][Full Text] [Related]
15. Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents.
Lamb DC; Kelly DE; Waterman MR; Stromstedt M; Rozman D; Kelly SL
Yeast; 1999 Jun; 15(9):755-63. PubMed ID: 10398344
[TBL] [Abstract][Full Text] [Related]
16. Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives.
Lewis DF; Wiseman A; Tarbit MH
J Enzyme Inhib; 1999; 14(3):175-92. PubMed ID: 10445042
[TBL] [Abstract][Full Text] [Related]
17. Cytochromes P450: novel drug targets in the war against multidrug-resistant Mycobacterium tuberculosis.
Munro AW; McLean KJ; Marshall KR; Warman AJ; Lewis G; Roitel O; Sutcliffe MJ; Kemp CA; Modi S; Scrutton NS; Leys D
Biochem Soc Trans; 2003 Jun; 31(Pt 3):625-30. PubMed ID: 12773169
[TBL] [Abstract][Full Text] [Related]
18. Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target.
Gurcha SS; Usha V; Cox JA; Fütterer K; Abrahams KA; Bhatt A; Alderwick LJ; Reynolds RC; Loman NJ; Nataraj V; Alemparte C; Barros D; Lloyd AJ; Ballell L; Hobrath JV; Besra GS
PLoS One; 2014; 9(11):e113568. PubMed ID: 25409504
[TBL] [Abstract][Full Text] [Related]
19. Potential drug targets in the Mycobacterium tuberculosis cytochrome P450 system.
Ortiz de Montellano PR
J Inorg Biochem; 2018 Mar; 180():235-245. PubMed ID: 29352597
[TBL] [Abstract][Full Text] [Related]
20. Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus.
Parker JE; Merkamm M; Manning NJ; Pompon D; Kelly SL; Kelly DE
Antimicrob Agents Chemother; 2008 Oct; 52(10):3597-603. PubMed ID: 18694951
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
