These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

96 related articles for article (PubMed ID: 11377379)

  • 1. Cellular pharmacokinetics and pharmacodynamics of the deoxycytidine analog 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine (CNDAC).
    Azuma A; Huang P; Matsuda A; Plunkett W
    Biochem Pharmacol; 2001 Jun; 61(12):1497-507. PubMed ID: 11377379
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine: a novel anticancer nucleoside analog that causes both DNA strand breaks and G(2) arrest.
    Azuma A; Huang P; Matsuda A; Plunkett W
    Mol Pharmacol; 2001 Apr; 59(4):725-31. PubMed ID: 11259616
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nucleosides and nucleotides. 141. Chemical stability of a new antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine in alkaline medium: formation of 2'-C-cyano-2'-deoxy-1-beta-D-ribo-pentofuranosylcytosine and its antitumor activity.
    Azuma A; Hanaoka K; Kurihara A; Kobayashi T; Miyauchi S; Kamo N; Tanaka M; Sasaki T; Matsuda A
    J Med Chem; 1995 Aug; 38(17):3391-7. PubMed ID: 7650692
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitumor activity and novel DNA-self-strand-breaking mechanism of CNDAC (1-(2-C-cyano-2-deoxy-beta-D-arabino-pentofuranosyl) cytosine) and its N4-palmitoyl derivative (CS-682).
    Hanaoka K; Suzuki M; Kobayashi T; Tanzawa F; Tanaka K; Shibayama T; Miura S; Ikeda T; Iwabuchi H; Nakagawa A; Mitsuhashi Y; Hisaoka M; Kaneko M; Tomida A; Wataya Y; Nomura T; Sasaki T; Matsuda A; Tsuruo T; Kurakata S
    Int J Cancer; 1999 Jul; 82(2):226-36. PubMed ID: 10389757
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Design of a new antitumor nucleoside CNDAC, against solid tumors].
    Matsuda A
    Gan To Kagaku Ryoho; 1996 Jan; 23(2):202-10. PubMed ID: 8611048
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation.
    Liu X; Guo Y; Li Y; Jiang Y; Chubb S; Azuma A; Huang P; Matsuda A; Hittelman W; Plunkett W
    Cancer Res; 2005 Aug; 65(15):6874-81. PubMed ID: 16061671
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development and biochemical characterization of a 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine (CNDAC)-resistant variant of the human fibrosarcoma cell line HT-1080.
    Obata T; Endo Y; Tanaka M; Matsuda A; Sasaki T
    Cancer Lett; 1998 Jan; 123(1):53-61. PubMed ID: 9461018
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Repair of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair.
    Wang Y; Liu X; Matsuda A; Plunkett W
    Cancer Res; 2008 May; 68(10):3881-9. PubMed ID: 18483273
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sapacitabine, the prodrug of CNDAC, is a nucleoside analog with a unique action mechanism of inducing DNA strand breaks.
    Liu XJ; Nowak B; Wang YQ; Plunkett W
    Chin J Cancer; 2012 Aug; 31(8):373-80. PubMed ID: 22739266
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism-Based Drug Combinations with the DNA Strand-Breaking Nucleoside Analog CNDAC.
    Liu X; Jiang Y; Nowak B; Hargis S; Plunkett W
    Mol Cancer Ther; 2016 Oct; 15(10):2302-2313. PubMed ID: 27474148
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Action of 2',2'-difluorodeoxycytidine on DNA synthesis.
    Huang P; Chubb S; Hertel LW; Grindey GB; Plunkett W
    Cancer Res; 1991 Nov; 51(22):6110-7. PubMed ID: 1718594
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting and anti-tumor efficacy of liposomal 5'-O-dipalmitoylphosphatidyl 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine in mice lung bearing B16BL6 melanoma.
    Asai T; Shuto S; Matsuda A; Kakiuchi T; Ohba H; Tsukada H; Oku N
    Cancer Lett; 2001 Jan; 162(1):49-56. PubMed ID: 11121862
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Determinants in chemosensitivity of oncogene-transformed NIH3T3 cells to 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine.
    Zhang M; Endo Y; Sasaki T
    Int J Oncol; 1999 Mar; 14(3):543-9. PubMed ID: 10024689
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nucleosides and nucleotides. 100. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosyl-cytosine (CNDAC): design of a potential mechanism-based DNA-strand-breaking antineoplastic nucleoside.
    Matsuda A; Nakajima Y; Azuma A; Tanaka M; Sasaki T
    J Med Chem; 1991 Sep; 34(9):2917-9. PubMed ID: 1895307
    [No Abstract]   [Full Text] [Related]  

  • 15. Antitumor activity of 5'-O-dipalmitoylphosphatidyl 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine is enhanced by long-circulating liposomalization.
    Asai T; Kurohane K; Shuto S; Awano H; Matsuda A; Tsukada H; Namba Y; Okada S; Oku N
    Biol Pharm Bull; 1998 Jul; 21(7):766-71. PubMed ID: 9703265
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cyclopentenyl cytosine increases the phosphorylation and incorporation into DNA of 1-beta-D-arabinofuranosyl cytosine in a human T-lymphoblastic cell line.
    Verschuur AC; Van Gennip AH; Leen R; Voûte PA; Brinkman J; Van Kuilenburg AB
    Int J Cancer; 2002 Apr; 98(4):616-23. PubMed ID: 11920624
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Homologous recombination as a resistance mechanism to replication-induced double-strand breaks caused by the antileukemia agent CNDAC.
    Liu X; Wang Y; Benaissa S; Matsuda A; Kantarjian H; Estrov Z; Plunkett W
    Blood; 2010 Sep; 116(10):1737-46. PubMed ID: 20479284
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TDP1 is Critical for the Repair of DNA Breaks Induced by Sapacitabine, a Nucleoside also Targeting ATM- and BRCA-Deficient Tumors.
    Al Abo M; Sasanuma H; Liu X; Rajapakse VN; Huang SY; Kiselev E; Takeda S; Plunkett W; Pommier Y
    Mol Cancer Ther; 2017 Nov; 16(11):2543-2551. PubMed ID: 28802254
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Analysis of the prolonged infusion of DFP-10917, a deoxycytidine analog, as a therapeutic strategy for the treatment of human tumor xenografts in vivo.
    Iizuka K; Zhang C; Eshima K; Jin C; Eshima K; Fukushima M
    Int J Oncol; 2018 Mar; 52(3):851-860. PubMed ID: 29344636
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum.
    Azuma A; Nakajima Y; Nishizono N; Minakawa N; Suzuki M; Hanaoka K; Kobayashi T; Tanaka M; Sasaki T; Matsuda A
    J Med Chem; 1993 Dec; 36(26):4183-9. PubMed ID: 8277499
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.