BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

661 related articles for article (PubMed ID: 11382771)

  • 1. Residual ataxia telangiectasia mutated protein function in cells from ataxia telangiectasia patients, with 5762ins137 and 7271T-->G mutations, showing a less severe phenotype.
    Stewart GS; Last JI; Stankovic T; Haites N; Kidd AM; Byrd PJ; Taylor AM
    J Biol Chem; 2001 Aug; 276(32):30133-41. PubMed ID: 11382771
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Adult-onset ataxia telangiectasia due to ATM 5762ins137 mutation homozygosity.
    Sutton IJ; Last JI; Ritchie SJ; Harrington HJ; Byrd PJ; Taylor AM
    Ann Neurol; 2004 Jun; 55(6):891-5. PubMed ID: 15174027
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage.
    Bar-Shira A; Rashi-Elkeles S; Zlochover L; Moyal L; Smorodinsky NI; Seger R; Shiloh Y
    Oncogene; 2002 Jan; 21(5):849-55. PubMed ID: 11850813
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ATM complexes with HDM2 and promotes its rapid phosphorylation in a p53-independent manner in normal and tumor human cells exposed to ionizing radiation.
    de Toledo SM; Azzam EI; Dahlberg WK; Gooding TB; Little JB
    Oncogene; 2000 Dec; 19(54):6185-93. PubMed ID: 11175332
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis.
    Taylor AM; Groom A; Byrd PJ
    DNA Repair (Amst); 2004; 3(8-9):1219-25. PubMed ID: 15279810
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differing effects of breast cancer 1, early onset (BRCA1) and ataxia-telangiectasia mutated (ATM) mutations on cellular responses to ionizing radiation.
    Mamon HJ; Dahlberg W; Azzam EI; Nagasawa H; Muto MG; Little JB
    Int J Radiat Biol; 2003 Oct; 79(10):817-29. PubMed ID: 14630541
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.
    Pereg Y; Shkedy D; de Graaf P; Meulmeester E; Edelson-Averbukh M; Salek M; Biton S; Teunisse AF; Lehmann WD; Jochemsen AG; Shiloh Y
    Proc Natl Acad Sci U S A; 2005 Apr; 102(14):5056-61. PubMed ID: 15788536
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Defective p53 response and apoptosis associated with an ataxia-telangiectasia-like phenotype.
    Gueven N; Becherel OJ; Birrell G; Chen P; DelSal G; Carney JP; Grattan-Smith P; Lavin MF
    Cancer Res; 2006 Mar; 66(6):2907-12. PubMed ID: 16540636
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
    Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
    Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.
    Kang J; Ferguson D; Song H; Bassing C; Eckersdorff M; Alt FW; Xu Y
    Mol Cell Biol; 2005 Jan; 25(2):661-70. PubMed ID: 15632067
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Contribution of the Atm protein to maintaining cellular homeostasis evidenced by continuous activation of the AP-1 pathway in Atm-deficient brains.
    Weizman N; Shiloh Y; Barzilai A
    J Biol Chem; 2003 Feb; 278(9):6741-7. PubMed ID: 12496286
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATM mutations and phenotypes in ataxia-telangiectasia families in the British Isles: expression of mutant ATM and the risk of leukemia, lymphoma, and breast cancer.
    Stankovic T; Kidd AM; Sutcliffe A; McGuire GM; Robinson P; Weber P; Bedenham T; Bradwell AR; Easton DF; Lennox GG; Haites N; Byrd PJ; Taylor AM
    Am J Hum Genet; 1998 Feb; 62(2):334-45. PubMed ID: 9463314
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The p53-mediated DNA damage response to ionizing radiation in fibroblasts from ataxia-without-telangiectasia patients.
    Jongmans W; Vuillaume M; Kleijer WJ; Lakin ND; Hall J
    Int J Radiat Biol; 1998 Sep; 74(3):287-95. PubMed ID: 9737532
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role for ATM in DNA damage-induced phosphorylation of BRCA1.
    Gatei M; Scott SP; Filippovitch I; Soronika N; Lavin MF; Weber B; Khanna KK
    Cancer Res; 2000 Jun; 60(12):3299-304. PubMed ID: 10866324
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia.
    Lavin MF; Khanna KK
    Int J Radiat Biol; 1999 Oct; 75(10):1201-14. PubMed ID: 10549596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage.
    Khosravi R; Maya R; Gottlieb T; Oren M; Shiloh Y; Shkedy D
    Proc Natl Acad Sci U S A; 1999 Dec; 96(26):14973-7. PubMed ID: 10611322
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex.
    Lee JH; Paull TT
    Science; 2004 Apr; 304(5667):93-6. PubMed ID: 15064416
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional and computational assessment of missense variants in the ataxia-telangiectasia mutated (ATM) gene: mutations with increased cancer risk.
    Mitui M; Nahas SA; Du LT; Yang Z; Lai CH; Nakamura K; Arroyo S; Scott S; Purayidom A; Concannon P; Lavin M; Gatti RA
    Hum Mutat; 2009 Jan; 30(1):12-21. PubMed ID: 18634022
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks.
    Kishi S; Zhou XZ; Ziv Y; Khoo C; Hill DE; Shiloh Y; Lu KP
    J Biol Chem; 2001 Aug; 276(31):29282-91. PubMed ID: 11375976
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder.
    Stewart GS; Maser RS; Stankovic T; Bressan DA; Kaplan MI; Jaspers NG; Raams A; Byrd PJ; Petrini JH; Taylor AM
    Cell; 1999 Dec; 99(6):577-87. PubMed ID: 10612394
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.