These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 11384242)

  • 1. Structure-activity studies for a novel series of bicyclic substituted hexahydrobenz[e]isoindole alpha1A adrenoceptor antagonists as potential agents for the symptomatic treatment of benign prostatic hyperplasia.
    Meyer MD; Altenbach RJ; Bai H; Basha FZ; Carroll WA; Kerwin JF; Lebold SA; Lee E; Pratt JK; Sippy KB; Tietje K; Wendt MD; Brune ME; Buckner SA; Hancock AA; Drizin I
    J Med Chem; 2001 Jun; 44(12):1971-85. PubMed ID: 11384242
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity studies for a novel series of tricyclic substituted hexahydrobenz[e]isoindole alpha(1A) adrenoceptor antagonists as potential agents for the symptomatic treatment of benign prostatic hyperplasia (BPH).
    Meyer MD; Altenbach RJ; Basha FZ; Carroll WA; Condon S; Elmore SW; Kerwin JF; Sippy KB; Tietje K; Wendt MD; Hancock AA; Brune ME; Buckner SA; Drizin I
    J Med Chem; 2000 Apr; 43(8):1586-603. PubMed ID: 10780916
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of novel alpha1a adrenoceptor-selective dihydropyridine antagonists for the treatment of benign prostatic hyperplasia.
    Nagarathnam D; Wetzel JM; Miao SW; Marzabadi MR; Chiu G; Wong WC; Hong X; Fang J; Forray C; Branchek TA; Heydorn WE; Chang RS; Broten T; Schorn TW; Gluchowski C
    J Med Chem; 1998 Dec; 41(26):5320-33. PubMed ID: 9857099
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and biological activity of prazosin-related antagonists. Role of the piperazine and furan units of prazosin on the selectivity for alpha1-adrenoreceptor subtypes.
    Bolognesi ML; Budriesi R; Chiarini A; Poggesi E; Leonardi A; Melchiorre C
    J Med Chem; 1998 Nov; 41(24):4844-53. PubMed ID: 9822553
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel heterocycles as selective alpha1-adrenergic receptor antagonists.
    Li X; McCoy KA; Murray WV; Jolliffe L; Pulito V
    Bioorg Med Chem Lett; 2000 Oct; 10(20):2375-7. PubMed ID: 11055359
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of specific binding of [125I]L-762,459, a selective alpha1A-adrenoceptor radioligand to rat and human tissues.
    O'Malley SS; Chen TB; Francis BE; Gibson RE; Burns HD; DiSalvo J; Bayne ML; Wetzel JM; Nagarathnam D; Marzabadi M; Gluchowski C; Chang RS
    Eur J Pharmacol; 1998 May; 348(2-3):287-95. PubMed ID: 9652345
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Revisiting the Pharmacodynamic Uroselectivity of
    Quaresma BMCS; Pimenta AR; Santos da Silva AC; Pupo AS; Romeiro LAS; Silva CLM; Noël F
    J Pharmacol Exp Ther; 2019 Oct; 371(1):106-112. PubMed ID: 31285236
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro alpha1-adrenoceptor pharmacology of Ro 70-0004 and RS-100329, novel alpha1A-adrenoceptor selective antagonists.
    Williams TJ; Blue DR; Daniels DV; Davis B; Elworthy T; Gever JR; Kava MS; Morgans D; Padilla F; Tassa S; Vimont RL; Chapple CR; Chess-Williams R; Eglen RM; Clarke DE; Ford AP
    Br J Pharmacol; 1999 May; 127(1):252-8. PubMed ID: 10369480
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RBx 6198: a novel alpha1-adrenoceptor antagonist for the treatment of benign prostatic hyperplasia.
    Nanda K; Naruganahalli KS; Gupta S; Malhotra S; Tiwari A; Hegde LG; Jain S; Sinha N; Gupta JB; Chugh A; Anand N; Ray A
    Eur J Pharmacol; 2009 Apr; 607(1-3):213-9. PubMed ID: 19239913
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of the pharmacological selectivity profile of alpha 1 adrenoceptor antagonists at prostatic alpha 1 adrenoceptors: binding, functional and in vivo studies.
    Kenny BA; Miller AM; Williamson IJ; O'Connell J; Chalmers DH; Naylor AM
    Br J Pharmacol; 1996 Jun; 118(4):871-8. PubMed ID: 8799556
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Search for alpha 1-adrenoceptor subtypes selective antagonists: design, synthesis and biological activity of cystazosin, an alpha 1D-adrenoceptor antagonist.
    Minarini A; Budriesi R; Chiarini A; Leonardi A; Melchiorre C
    Bioorg Med Chem Lett; 1998 Jun; 8(11):1353-8. PubMed ID: 9871765
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and pharmacological characterization of 3-[2-((3aR,9bR)-cis-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e] isoindol-2-yl)ethyl]pyrido-[3',4':4,5]thieno[3,2-d]pyrimidine-2,4 (1H,3H)-dione (A-131701): a uroselective alpha 1A adrenoceptor antagonist for the symptomatic treatment of benign prostatic hyperplasia.
    Meyer MD; Altenbach RJ; Basha FZ; Carroll WA; Drizin I; Elmore SW; Ehrlich PP; Lebold SA; Tietje K; Sippy KB; Wendt MD; Plata DJ; Plagge F; Buckner SA; Brune ME; Hancock AA; Kerwin JF
    J Med Chem; 1997 Sep; 40(20):3141-3. PubMed ID: 9379432
    [No Abstract]   [Full Text] [Related]  

  • 13. Analogues of prazosin that bear a benextramine-related polyamine backbone exhibit different antagonism toward alpha1-adrenoreceptor subtypes.
    Bolognesi ML; Marucci G; Angeli P; Buccioni M; Minarini A; Rosini M; Tumiatti V; Melchiorre C
    J Med Chem; 2001 Feb; 44(3):362-71. PubMed ID: 11462977
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vivo study on the effects of alpha1-adrenoceptor antagonists on intraurethral pressure in the prostatic urethra and intraluminal pressure in the vas deferens in male dogs.
    Noguchi Y; Ohtake A; Suzuki M; Sasamata M
    Eur J Pharmacol; 2008 Feb; 580(1-2):256-61. PubMed ID: 18078926
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacological analysis of the novel, selective alpha1-adrenoceptor antagonist, KMD-3213, and its suitability as a tritiated radioligand.
    Murata S; Taniguchi T; Muramatsu I
    Br J Pharmacol; 1999 May; 127(1):19-26. PubMed ID: 10369451
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Apoptotic impact of alpha1-blockers on prostate cancer growth: a myth or an inviting reality?
    Tahmatzopoulos A; Kyprianou N
    Prostate; 2004 Apr; 59(1):91-100. PubMed ID: 14991869
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and alpha(1)-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+)-cyclazosin.
    Sagratini G; Angeli P; Buccioni M; Gulini U; Marucci G; Melchiorre C; Leonardi A; Poggesi E; Giardinà D
    Bioorg Med Chem; 2007 Mar; 15(6):2334-45. PubMed ID: 17276073
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 2. Approaches to eliminate opioid agonist metabolites via modification of linker and 4-methoxycarbonyl-4-phenylpiperidine moiety.
    Murali Dhar TG; Nagarathnam D; Marzabadi MR; Lagu B; Wong WC; Chiu G; Tyagarajan S; Miao SW; Zhang F; Sun W; Tian D; Shen Q; Zhang J; Wetzel JM; Forray C; Chang RS; Broten TP; Schorn TW; Chen TB; O'Malley S; Ransom R; Schneck K; Bendesky R; Harrell CM; Vyas KP
    J Med Chem; 1999 Nov; 42(23):4778-93. PubMed ID: 10579841
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of some novel alpha 1-adrenoceptor antagonists in human hyperplastic prostate.
    Chueh SC; Chern JW; Choong CM; Guh JH; Teng CM
    Eur J Pharmacol; 2002 Jun; 445(1-2):125-31. PubMed ID: 12065203
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 1-Arylpiperazinyl-4-cyclohexylamine derived isoindole-1,3-diones as potent and selective alpha-1a/1d adrenergic receptor ligands.
    Li S; Chiu G; Pulito VL; Liu J; Connolly PJ; Middleton SA
    Bioorg Med Chem Lett; 2007 Mar; 17(6):1646-50. PubMed ID: 17254786
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.