68 related articles for article (PubMed ID: 11388772)
1. Repression of cellular anaplerosis as the hypothesized mechanism of gamma-linolenic acid-induced toxicity to tumor cells.
Nwankwo JO
Med Hypotheses; 2001 May; 56(5):582-8. PubMed ID: 11388772
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis.
Menendez JA; Colomer R; Lupu R
Med Hypotheses; 2005; 64(2):337-41. PubMed ID: 15607568
[TBL] [Abstract][Full Text] [Related]
3. Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis.
Menendez JA; Ropero S; Mehmi I; Atlas E; Colomer R; Lupu R
Int J Oncol; 2004 Jun; 24(6):1369-83. PubMed ID: 15138577
[TBL] [Abstract][Full Text] [Related]
4. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
Menendez JA; Mehmi I; Atlas E; Colomer R; Lupu R
Int J Oncol; 2004 Mar; 24(3):591-608. PubMed ID: 14767544
[TBL] [Abstract][Full Text] [Related]
5. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity.
Thupari JN; Pinn ML; Kuhajda FP
Biochem Biophys Res Commun; 2001 Jul; 285(2):217-23. PubMed ID: 11444828
[TBL] [Abstract][Full Text] [Related]
6. RNA interference-mediated silencing of the p53 tumor-suppressor protein drastically increases apoptosis after inhibition of endogenous fatty acid metabolism in breast cancer cells.
Menendez JA; Lupu R
Int J Mol Med; 2005 Jan; 15(1):33-40. PubMed ID: 15583825
[TBL] [Abstract][Full Text] [Related]
7. Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts.
Pizer ES; Thupari J; Han WF; Pinn ML; Chrest FJ; Frehywot GL; Townsend CA; Kuhajda FP
Cancer Res; 2000 Jan; 60(2):213-8. PubMed ID: 10667561
[TBL] [Abstract][Full Text] [Related]
8. Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells.
Zhou W; Han WF; Landree LE; Thupari JN; Pinn ML; Bililign T; Kim EK; Vadlamudi A; Medghalchi SM; El Meskini R; Ronnett GV; Townsend CA; Kuhajda FP
Cancer Res; 2007 Apr; 67(7):2964-71. PubMed ID: 17409402
[TBL] [Abstract][Full Text] [Related]
9. Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells.
Zhou W; Simpson PJ; McFadden JM; Townsend CA; Medghalchi SM; Vadlamudi A; Pinn ML; Ronnett GV; Kuhajda FP
Cancer Res; 2003 Nov; 63(21):7330-7. PubMed ID: 14612531
[TBL] [Abstract][Full Text] [Related]
10. Malonyl-CoA decarboxylase inhibition is selectively cytotoxic to human breast cancer cells.
Zhou W; Tu Y; Simpson PJ; Kuhajda FP
Oncogene; 2009 Aug; 28(33):2979-87. PubMed ID: 19543323
[TBL] [Abstract][Full Text] [Related]
11. Biochemical considerations regarding cellular regulation through messenger and allosteric systems. Antagonism between catabolic oxidation of free fatty acids and anabolic aerobic glycolysis in the liver.
Belloiu DD
Endocrinologie; 1990; 28(1):3-13. PubMed ID: 2080418
[TBL] [Abstract][Full Text] [Related]
12. Fatty acid synthase: a metabolic oncogene in prostate cancer?
Baron A; Migita T; Tang D; Loda M
J Cell Biochem; 2004 Jan; 91(1):47-53. PubMed ID: 14689581
[TBL] [Abstract][Full Text] [Related]
13. Pharmacological inhibitors of mammalian fatty acid synthase suppress DNA replication and induce apoptosis in tumor cell lines.
Pizer ES; Chrest FJ; DiGiuseppe JA; Han WF
Cancer Res; 1998 Oct; 58(20):4611-5. PubMed ID: 9788612
[TBL] [Abstract][Full Text] [Related]
14. Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation.
Dyck JR; Cheng JF; Stanley WC; Barr R; Chandler MP; Brown S; Wallace D; Arrhenius T; Harmon C; Yang G; Nadzan AM; Lopaschuk GD
Circ Res; 2004 May; 94(9):e78-84. PubMed ID: 15105298
[TBL] [Abstract][Full Text] [Related]
15. Characterization and inhibition of fatty acid synthase in pediatric tumor cell lines.
Slade RF; Hunt DA; Pochet MM; Venema VJ; Hennigar RA
Anticancer Res; 2003; 23(2B):1235-43. PubMed ID: 12820377
[TBL] [Abstract][Full Text] [Related]
16. Mechanism of apoptosis induced by the inhibition of fatty acid synthase in breast cancer cells.
Bandyopadhyay S; Zhan R; Wang Y; Pai SK; Hirota S; Hosobe S; Takano Y; Saito K; Furuta E; Iiizumi M; Mohinta S; Watabe M; Chalfant C; Watabe K
Cancer Res; 2006 Jun; 66(11):5934-40. PubMed ID: 16740734
[TBL] [Abstract][Full Text] [Related]
17. Selective inhibition of fatty acid synthase for lung cancer treatment.
Orita H; Coulter J; Lemmon C; Tully E; Vadlamudi A; Medghalchi SM; Kuhajda FP; Gabrielson E
Clin Cancer Res; 2007 Dec; 13(23):7139-45. PubMed ID: 18056164
[TBL] [Abstract][Full Text] [Related]
18. Fatty acid-induced effect on glucagon secretion is mediated via fatty acid oxidation.
Hong J; Jeppesen PB; Nordentoft I; Hermansen K
Diabetes Metab Res Rev; 2007 Mar; 23(3):202-10. PubMed ID: 16802400
[TBL] [Abstract][Full Text] [Related]
19. RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells.
Brusselmans K; De Schrijver E; Verhoeven G; Swinnen JV
Cancer Res; 2005 Aug; 65(15):6719-25. PubMed ID: 16061653
[TBL] [Abstract][Full Text] [Related]
20. Theanaphthoquinone inhibits fatty acid synthase expression in EGF-stimulated human breast cancer cells via the regulation of EGFR/ErbB-2 signaling.
Weng MS; Ho CT; Ho YS; Lin JK
Toxicol Appl Pharmacol; 2007 Jan; 218(2):107-18. PubMed ID: 17182072
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]