141 related articles for article (PubMed ID: 11392618)
1. The conformational switch in muscarinic acetylcholine receptors.
Hulme EC; Lu ZL; Bee M; Curtis CA; Saldanha J
Life Sci; 2001 Apr; 68(22-23):2495-500. PubMed ID: 11392618
[TBL] [Abstract][Full Text] [Related]
2. Transmembrane domains 4 and 7 of the M(1) muscarinic acetylcholine receptor are critical for ligand binding and the receptor activation switch.
Lu ZL; Saldanha JW; Hulme EC
J Biol Chem; 2001 Sep; 276(36):34098-104. PubMed ID: 11441014
[TBL] [Abstract][Full Text] [Related]
3. Seven-transmembrane receptors: crystals clarify.
Lu ZL; Saldanha JW; Hulme EC
Trends Pharmacol Sci; 2002 Mar; 23(3):140-6. PubMed ID: 11879682
[TBL] [Abstract][Full Text] [Related]
4. Constitutively active muscarinic receptors.
Spalding TA; Burstein ES
Life Sci; 2001 Apr; 68(22-23):2511-6. PubMed ID: 11392620
[TBL] [Abstract][Full Text] [Related]
5. The conformational switch in 7-transmembrane receptors: the muscarinic receptor paradigm.
Hulme EC; Lu ZL; Ward SD; Allman K; Curtis CA
Eur J Pharmacol; 1999 Jun; 375(1-3):247-60. PubMed ID: 10443581
[TBL] [Abstract][Full Text] [Related]
6. A network of conserved intramolecular contacts defines the off-state of the transmembrane switch mechanism in a seven-transmembrane receptor.
Lu ZL; Hulme EC
J Biol Chem; 2000 Feb; 275(8):5682-6. PubMed ID: 10681552
[TBL] [Abstract][Full Text] [Related]
7. Random mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast. Identification of point mutations that "silence" a constitutively active mutant M3 receptor and greatly impair receptor/G protein coupling.
Schmidt C; Li B; Bloodworth L; Erlenbach I; Zeng FY; Wess J
J Biol Chem; 2003 Aug; 278(32):30248-60. PubMed ID: 12750375
[TBL] [Abstract][Full Text] [Related]
8. Multiple allosteric sites on muscarinic receptors.
Birdsall NJ; Lazareno S; Popham A; Saldanha J
Life Sci; 2001 Apr; 68(22-23):2517-24. PubMed ID: 11392621
[TBL] [Abstract][Full Text] [Related]
9. Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor.
Han SJ; Hamdan FF; Kim SK; Jacobson KA; Bloodworth LM; Li B; Wess J
J Biol Chem; 2005 Oct; 280(41):34849-58. PubMed ID: 16093246
[TBL] [Abstract][Full Text] [Related]
10. The functional role of the binding site aspartate in muscarinic acetylcholine receptors, probed by site-directed mutagenesis.
Page KM; Curtis CA; Jones PG; Hulme EC
Eur J Pharmacol; 1995 May; 289(3):429-37. PubMed ID: 7556411
[TBL] [Abstract][Full Text] [Related]
11. Structure and activation of muscarinic acetylcholine receptors.
Hulme EC; Lu ZL; Saldanha JW; Bee MS
Biochem Soc Trans; 2003 Feb; 31(Pt 1):29-34. PubMed ID: 12546648
[TBL] [Abstract][Full Text] [Related]
12. Structure-function analysis of muscarinic receptors and their associated G proteins.
Kostenis E; Zeng FY; Wess J
Life Sci; 1999; 64(6-7):355-62. PubMed ID: 10069496
[TBL] [Abstract][Full Text] [Related]
13. Modelling of the binding site of the human m1 muscarinic receptor: experimental validation and refinement.
Bourdon H; Trumpp-Kallmeyer S; Schreuder H; Hoflack J; Hibert M; Wermuth CG
J Comput Aided Mol Des; 1997 Jul; 11(4):317-32. PubMed ID: 9334899
[TBL] [Abstract][Full Text] [Related]
14. Conformational changes that occur during M3 muscarinic acetylcholine receptor activation probed by the use of an in situ disulfide cross-linking strategy.
Ward SD; Hamdan FF; Bloodworth LM; Wess J
J Biol Chem; 2002 Jan; 277(3):2247-57. PubMed ID: 11698401
[TBL] [Abstract][Full Text] [Related]
15. Molecular basis of muscarinic acetylcholine receptor function.
Wess J
Trends Pharmacol Sci; 1993 Aug; 14(8):308-13. PubMed ID: 8249149
[TBL] [Abstract][Full Text] [Related]
16. Use of an in situ disulfide cross-linking strategy to map proximities between amino acid residues in transmembrane domains I and VII of the M3 muscarinic acetylcholine receptor.
Hamdan FF; Ward SD; Siddiqui NA; Bloodworth LM; Wess J
Biochemistry; 2002 Jun; 41(24):7647-58. PubMed ID: 12056896
[TBL] [Abstract][Full Text] [Related]
17. Alanine-scanning mutagenesis of transmembrane domain 6 of the M(1) muscarinic acetylcholine receptor suggests that Tyr381 plays key roles in receptor function.
Ward SD; Curtis CA; Hulme EC
Mol Pharmacol; 1999 Nov; 56(5):1031-41. PubMed ID: 10531410
[TBL] [Abstract][Full Text] [Related]
18. Muscarinic acetylcholine receptors: structural basis of ligand binding and G protein coupling.
Wess J; Blin N; Mutschler E; Blüml K
Life Sci; 1995; 56(11-12):915-22. PubMed ID: 10188793
[TBL] [Abstract][Full Text] [Related]
19. Scanning mutagenesis of transmembrane domain 3 of the M1 muscarinic acetylcholine receptor.
Hulme EC; Lu ZL
J Physiol Paris; 1998; 92(3-4):269-74. PubMed ID: 9789821
[TBL] [Abstract][Full Text] [Related]
20. Roof and floor of the muscarinic binding pocket: variations in the binding modes of orthosteric ligands.
Goodwin JA; Hulme EC; Langmead CJ; Tehan BG
Mol Pharmacol; 2007 Dec; 72(6):1484-96. PubMed ID: 17848601
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
