138 related articles for article (PubMed ID: 11395484)
1. Opposing effects of molecular volume and charge at the hyperekplexia site alpha 1(P250) govern glycine receptor activation and desensitization.
Breitinger HG; Villmann C; Becker K; Becker CM
J Biol Chem; 2001 Aug; 276(32):29657-63. PubMed ID: 11395484
[TBL] [Abstract][Full Text] [Related]
2. Statistical coassembly of glycine receptor alpha1 wildtype and the hyperekplexia mutant alpha1(P250T) in HEK 293 cells: impaired channel function is not dominant in the recombinant system.
Breitinger HG; Becker CM
Neurosci Lett; 2002 Oct; 331(1):21-4. PubMed ID: 12359314
[TBL] [Abstract][Full Text] [Related]
3. Molecular dynamics simulation links conformation of a pore-flanking region to hyperekplexia-related dysfunction of the inhibitory glycine receptor.
Breitinger HG; Lanig H; Vohwinkel C; Grewer C; Breitinger U; Clark T; Becker CM
Chem Biol; 2004 Oct; 11(10):1339-50. PubMed ID: 15489161
[TBL] [Abstract][Full Text] [Related]
4. A Missense Mutation A384P Associated with Human Hyperekplexia Reveals a Desensitization Site of Glycine Receptors.
Wang CH; Hernandez CC; Wu J; Zhou N; Hsu HY; Shen ML; Wang YC; Macdonald RL; Wu DC
J Neurosci; 2018 Mar; 38(11):2818-2831. PubMed ID: 29440552
[TBL] [Abstract][Full Text] [Related]
5. A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor.
Schofield CM; Jenkins A; Harrison NL
J Biol Chem; 2003 Sep; 278(36):34079-83. PubMed ID: 12826676
[TBL] [Abstract][Full Text] [Related]
6. Novel GLRA1 missense mutation (P250T) in dominant hyperekplexia defines an intracellular determinant of glycine receptor channel gating.
Saul B; Kuner T; Sobetzko D; Brune W; Hanefeld F; Meinck HM; Becker CM
J Neurosci; 1999 Feb; 19(3):869-77. PubMed ID: 9920650
[TBL] [Abstract][Full Text] [Related]
7. Identification of a new ligand binding domain in the alpha1 subunit of the inhibitory glycine receptor.
Vafa B; Lewis TM; Cunningham AM; Jacques P; Lynch JW; Schofield PR
J Neurochem; 1999 Nov; 73(5):2158-66. PubMed ID: 10537076
[TBL] [Abstract][Full Text] [Related]
8. Molecular determinants of proton modulation of glycine receptors.
Chen Z; Dillon GH; Huang R
J Biol Chem; 2004 Jan; 279(2):876-83. PubMed ID: 14563849
[TBL] [Abstract][Full Text] [Related]
9. Murine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation.
Wilkins ME; Caley A; Gielen MC; Harvey RJ; Smart TG
J Physiol; 2016 Jul; 594(13):3589-607. PubMed ID: 27028707
[TBL] [Abstract][Full Text] [Related]
10. Stoichiometry of recombinant heteromeric glycine receptors revealed by a pore-lining region point mutation.
Burzomato V; Groot-Kormelink PJ; Sivilotti LG; Beato M
Recept Channels; 2003; 9(6):353-61. PubMed ID: 14698963
[TBL] [Abstract][Full Text] [Related]
11. New hyperekplexia mutations provide insight into glycine receptor assembly, trafficking, and activation mechanisms.
Bode A; Wood SE; Mullins JGL; Keramidas A; Cushion TD; Thomas RH; Pickrell WO; Drew CJG; Masri A; Jones EA; Vassallo G; Born AP; Alehan F; Aharoni S; Bannasch G; Bartsch M; Kara B; Krause A; Karam EG; Matta S; Jain V; Mandel H; Freilinger M; Graham GE; Hobson E; Chatfield S; Vincent-Delorme C; Rahme JE; Afawi Z; Berkovic SF; Howell OW; Vanbellinghen JF; Rees MI; Chung SK; Lynch JW
J Biol Chem; 2013 Nov; 288(47):33745-33759. PubMed ID: 24108130
[TBL] [Abstract][Full Text] [Related]
12. Function of hyperekplexia-causing α1R271Q/L glycine receptors is restored by shifting the affected residue out of the allosteric signalling pathway.
Shan Q; Han L; Lynch JW
Br J Pharmacol; 2012 Apr; 165(7):2113-23. PubMed ID: 21955162
[TBL] [Abstract][Full Text] [Related]
13. Selective antagonism of rat inhibitory glycine receptor subunits.
Han Y; Li P; Slaughter MM
J Physiol; 2004 Feb; 554(Pt 3):649-58. PubMed ID: 14645455
[TBL] [Abstract][Full Text] [Related]
14. The Startle Disease Mutation E103K Impairs Activation of Human Homomeric α1 Glycine Receptors by Disrupting an Intersubunit Salt Bridge across the Agonist Binding Site.
Safar F; Hurdiss E; Erotocritou M; Greiner T; Lape R; Irvine MW; Fang G; Jane D; Yu R; Dämgen MA; Biggin PC; Sivilotti LG
J Biol Chem; 2017 Mar; 292(12):5031-5042. PubMed ID: 28174298
[TBL] [Abstract][Full Text] [Related]
15. Recessive hyperekplexia mutations of the glycine receptor alpha1 subunit affect cell surface integration and stability.
Villmann C; Oertel J; Melzer N; Becker CM
J Neurochem; 2009 Nov; 111(3):837-47. PubMed ID: 19732286
[TBL] [Abstract][Full Text] [Related]
16. A Novel Glycine Receptor Variant with Startle Disease Affects Syndapin I and Glycinergic Inhibition.
Langlhofer G; Schaefer N; Maric HM; Keramidas A; Zhang Y; Baumann P; Blum R; Breitinger U; Strømgaard K; Schlosser A; Kessels MM; Koch D; Qualmann B; Breitinger HG; Lynch JW; Villmann C
J Neurosci; 2020 Jun; 40(25):4954-4969. PubMed ID: 32354853
[TBL] [Abstract][Full Text] [Related]
17. Identification of an inhibitory Zn2+ binding site on the human glycine receptor alpha1 subunit.
Harvey RJ; Thomas P; James CH; Wilderspin A; Smart TG
J Physiol; 1999 Oct; 520 Pt 1(Pt 1):53-64. PubMed ID: 10517800
[TBL] [Abstract][Full Text] [Related]
18. Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor.
Absalom NL; Lewis TM; Kaplan W; Pierce KD; Schofield PR
J Biol Chem; 2003 Dec; 278(50):50151-7. PubMed ID: 14525990
[TBL] [Abstract][Full Text] [Related]
19. Single expressed glycine receptor domains reconstitute functional ion channels without subunit-specific desensitization behavior.
Meiselbach H; Vogel N; Langlhofer G; Stangl S; Schleyer B; Bahnassawy L; Sticht H; Breitinger HG; Becker CM; Villmann C
J Biol Chem; 2014 Oct; 289(42):29135-47. PubMed ID: 25143388
[TBL] [Abstract][Full Text] [Related]
20. Contributions of conserved residues at the gating interface of glycine receptors.
Pless SA; Leung AW; Galpin JD; Ahern CA
J Biol Chem; 2011 Oct; 286(40):35129-36. PubMed ID: 21835920
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
