BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 11401545)

  • 1. Cloning, overexpression, and purification of aminoglycoside antibiotic nucleotidyltransferase (2'')-Ia: conformational studies with bound substrates.
    Ekman DR; DiGiammarino EL; Wright E; Witter ED; Serpersu EH
    Biochemistry; 2001 Jun; 40(24):7017-24. PubMed ID: 11401545
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cloning, overexpression, and purification of aminoglycoside antibiotic 3-acetyltransferase-IIIb: conformational studies with bound substrates.
    Owston MA; Serpersu EH
    Biochemistry; 2002 Sep; 41(35):10764-70. PubMed ID: 12196014
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Solution studies of isepamicin and conformational comparisons between isepamicin and butirosin A when bound to an aminoglycoside 6'-N-acetyltransferase determined by NMR spectroscopy.
    DiGiammarino EL; Draker KA; Wright GD; Serpersu EH
    Biochemistry; 1998 Mar; 37(11):3638-44. PubMed ID: 9521682
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aminoglycoside antibiotics bound to aminoglycoside-detoxifying enzymes and RNA adopt similar conformations.
    Cox JR; Ekman DR; DiGiammarino EL; Akal-Strader A; Serpersu EH
    Cell Biochem Biophys; 2000; 33(3):297-308. PubMed ID: 11325047
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Isolation of aminoglycoside nucleotidyltransferase (2'')-Ia from inclusion bodies as active, monomeric enzyme.
    Wright E; Serpersu EH
    Protein Expr Purif; 2004 Jun; 35(2):373-80. PubMed ID: 15135416
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thermodynamics of an aminoglycoside modifying enzyme with low substrate promiscuity: The aminoglycoside N3 acetyltransferase-VIa.
    Kumar P; Serpersu EH
    Proteins; 2017 Jul; 85(7):1258-1265. PubMed ID: 28316100
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regiospecificity assignment for the reaction of kanamycin nucleotidyltransferase from Staphylococcus aureus.
    Gerratana B; Cleland WW; Reinhardt LA
    Biochemistry; 2001 Mar; 40(9):2964-71. PubMed ID: 11258908
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enzyme-substrate interactions with an antibiotic resistance enzyme: aminoglycoside nucleotidyltransferase(2'')-Ia characterized by kinetic and thermodynamic methods.
    Wright E; Serpersu EH
    Biochemistry; 2005 Aug; 44(34):11581-91. PubMed ID: 16114895
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thermodynamic characterization of a thermostable antibiotic resistance enzyme, the aminoglycoside nucleotidyltransferase (4').
    Jing X; Wright E; Bible AN; Peterson CB; Alexandre G; Bruce BD; Serpersu EH
    Biochemistry; 2012 Nov; 51(45):9147-55. PubMed ID: 23066871
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of solvent and protein dynamics in ligand recognition and inhibition of aminoglycoside adenyltransferase 2″-Ia.
    Bacot-Davis VR; Bassenden AV; Sprules T; Berghuis AM
    Protein Sci; 2017 Sep; 26(9):1852-1863. PubMed ID: 28734024
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural and molecular basis for resistance to aminoglycoside antibiotics by the adenylyltransferase ANT(2″)-Ia.
    Cox G; Stogios PJ; Savchenko A; Wright GD
    mBio; 2015 Jan; 6(1):. PubMed ID: 25564464
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparing aminoglycoside binding sites in bacterial ribosomal RNA and aminoglycoside modifying enzymes.
    Romanowska J; Reuter N; Trylska J
    Proteins; 2013 Jan; 81(1):63-80. PubMed ID: 22907688
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular identification of aminoglycoside-modifying enzymes in clinical isolates of Escherichia coli resistant to amoxicillin/clavulanic acid isolated in Spain.
    Fernández-Martínez M; Miró E; Ortega A; Bou G; González-López JJ; Oliver A; Pascual A; Cercenado E; Oteo J; Martínez-Martínez L; Navarro F;
    Int J Antimicrob Agents; 2015 Aug; 46(2):157-63. PubMed ID: 26022930
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular determinants of affinity for aminoglycoside binding to the aminoglycoside nucleotidyltransferase(2'')-Ia.
    Wright E; Serpersu EH
    Biochemistry; 2006 Aug; 45(34):10243-50. PubMed ID: 16922499
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multiple keys for a single lock: the unusual structural plasticity of the nucleotidyltransferase (4')/kanamycin complex.
    Matesanz R; Diaz JF; Corzana F; Santana AG; Bastida A; Asensio JL
    Chemistry; 2012 Mar; 18(10):2875-89. PubMed ID: 22298309
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural investigation of the antibiotic and ATP-binding sites in kanamycin nucleotidyltransferase.
    Pedersen LC; Benning MM; Holden HM
    Biochemistry; 1995 Oct; 34(41):13305-11. PubMed ID: 7577914
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ANT(9)-Ic, a Novel Chromosomally Encoded Aminoglycoside Nucleotidyltransferase from Brucella intermedia.
    Sheng X; Lu W; Li A; Lu J; Song C; Xu J; Dong Y; Fu C; Lin X; Zhu M; Bao Q; Li K
    Microbiol Spectr; 2023 Jun; 11(3):e0062023. PubMed ID: 37039640
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NMR studies of the MgATP binding site of adenylate kinase and of a 45-residue peptide fragment of the enzyme.
    Fry DC; Kuby SA; Mildvan AS
    Biochemistry; 1985 Aug; 24(17):4680-94. PubMed ID: 2998457
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NMR-based analysis of aminoglycoside recognition by the resistance enzyme ANT(4'): the pattern of OH/NH3(+) substitution determines the preferred antibiotic binding mode and is critical for drug inactivation.
    Revuelta J; Vacas T; Torrado M; Corzana F; Gonzalez C; Jiménez-Barbero J; Menendez M; Bastida A; Asensio JL
    J Am Chem Soc; 2008 Apr; 130(15):5086-103. PubMed ID: 18366171
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural characterization of aminoglycoside 4'-O-adenylyltransferase ANT(4')-IIb from Pseudomonas aeruginosa.
    Semper C; Stogios P; Meziane-Cherif D; Evdokimova E; Courvalin P; Savchenko A
    Protein Sci; 2020 Mar; 29(3):758-767. PubMed ID: 31891426
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.