BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 11402035)

  • 1. Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels.
    Kirschenbaum F; Hsu SC; Cordell B; McCarthy JV
    J Biol Chem; 2001 Aug; 276(33):30701-7. PubMed ID: 11402035
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling.
    Kirschenbaum F; Hsu SC; Cordell B; McCarthy JV
    J Biol Chem; 2001 Mar; 276(10):7366-75. PubMed ID: 11104755
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PS1 N- and C-terminal fragments form a complex that functions in APP processing and Notch signaling.
    Levitan D; Lee J; Song L; Manning R; Wong G; Parker E; Zhang L
    Proc Natl Acad Sci U S A; 2001 Oct; 98(21):12186-90. PubMed ID: 11593035
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Presenilin 1 regulates beta-catenin-mediated transcription in a glycogen synthase kinase-3-independent fashion.
    Palacino JJ; Murphy MP; Murayama O; Iwasaki K; Fujiwara M; Takashima A; Golde TE; Wolozin B
    J Biol Chem; 2001 Oct; 276(42):38563-9. PubMed ID: 11504726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau.
    Takashima A; Murayama M; Murayama O; Kohno T; Honda T; Yasutake K; Nihonmatsu N; Mercken M; Yamaguchi H; Sugihara S; Wolozin B
    Proc Natl Acad Sci U S A; 1998 Aug; 95(16):9637-41. PubMed ID: 9689133
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate.
    Twomey C; McCarthy JV
    FEBS Lett; 2006 Jul; 580(17):4015-20. PubMed ID: 16814287
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation.
    Tesco G; Kim TW; Diehlmann A; Beyreuther K; Tanzi RE
    J Biol Chem; 1998 Dec; 273(51):33909-14. PubMed ID: 9852041
    [TBL] [Abstract][Full Text] [Related]  

  • 8. C-terminal maturation fragments of presenilin 1 and 2 control secretion of APP alpha and A beta by human cells and are degraded by proteasome.
    da Costa CA; Ancolio K; Checler F
    Mol Med; 1999 Mar; 5(3):160-8. PubMed ID: 10404513
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein.
    Laudon H; Mathews PM; Karlström H; Bergman A; Farmery MR; Nixon RA; Winblad B; Gandy SE; Lendahl U; Lundkvist J; Näslund J
    J Neurochem; 2004 Apr; 89(1):44-53. PubMed ID: 15030388
    [TBL] [Abstract][Full Text] [Related]  

  • 10. GSK3 beta forms a tetrameric complex with endogenous PS1-CTF/NTF and beta-catenin. Effects of the D257/D385A and FAD-linked mutations.
    Tesco G; Tanzi RE
    Ann N Y Acad Sci; 2000; 920():227-32. PubMed ID: 11193155
    [TBL] [Abstract][Full Text] [Related]  

  • 11. gamma-Secretase complexes containing N- and C-terminal fragments of different presenilin origin retain normal gamma-secretase activity.
    Strömberg K; Hansson EM; Laudon H; Bergstedt S; Näslund J; Lundkvist J; Lendahl U
    J Neurochem; 2005 Nov; 95(3):880-90. PubMed ID: 16135086
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Subcellular localization of presenilin 2 endoproteolytic C-terminal fragments.
    Tekirian TL; Merriam DE; Marshansky V; Miller J; Crowley AC; Chan H; Ausiello D; Brown D; Buxbaum JD; Xia W; Wasco W
    Brain Res Mol Brain Res; 2001 Nov; 96(1-2):14-20. PubMed ID: 11731004
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway.
    Kang DE; Soriano S; Frosch MP; Collins T; Naruse S; Sisodia SS; Leibowitz G; Levine F; Koo EH
    J Neurosci; 1999 Jun; 19(11):4229-37. PubMed ID: 10341227
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oligomerization of human presenilin-1 fragments.
    Hébert SS; Godin C; Lévesque G
    FEBS Lett; 2003 Aug; 550(1-3):30-4. PubMed ID: 12935881
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence that intramolecular associations between presenilin domains are obligatory for endoproteolytic processing.
    Saura CA; Tomita T; Davenport F; Harris CL; Iwatsubo T; Thinakaran G
    J Biol Chem; 1999 May; 274(20):13818-23. PubMed ID: 10318786
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence for phosphorylation and oligomeric assembly of presenilin 1.
    Seeger M; Nordstedt C; Petanceska S; Kovacs DM; Gouras GK; Hahne S; Fraser P; Levesque L; Czernik AJ; George-Hyslop PS; Sisodia SS; Thinakaran G; Tanzi RE; Greengard P; Gandy S
    Proc Natl Acad Sci U S A; 1997 May; 94(10):5090-4. PubMed ID: 9144195
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proteolytic fragments of the Alzheimer's disease associated presenilins-1 and -2 are phosphorylated in vivo by distinct cellular mechanisms.
    Walter J; Grünberg J; Schindzielorz A; Haass C
    Biochemistry; 1998 Apr; 37(17):5961-7. PubMed ID: 9558331
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Homodimerization of presenilin N-terminal fragments is affected by mutations linked to Alzheimer's disease.
    Cervantes S; Gonzàlez-Duarte R; Marfany G
    FEBS Lett; 2001 Sep; 505(1):81-6. PubMed ID: 11557046
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Zebrafish (Danio rerio) presenilin promotes aberrant amyloid beta-peptide production and requires a critical aspartate residue for its function in amyloidogenesis.
    Leimer U; Lun K; Romig H; Walter J; Grünberg J; Brand M; Haass C
    Biochemistry; 1999 Oct; 38(41):13602-9. PubMed ID: 10521267
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased tau phosphorylation but absence of formation of neurofibrillary tangles in mice double transgenic for human tau and Alzheimer mutant (M146L) presenilin-1.
    Boutajangout A; Leroy K; Touchet N; Authelet M; Blanchard V; Tremp G; Pradier L; Brion JP
    Neurosci Lett; 2002 Jan; 318(1):29-33. PubMed ID: 11786218
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.