309 related articles for article (PubMed ID: 11409035)
1. Secretases as therapeutic targets for the treatment of Alzheimer's disease.
Dominguez DI; De Strooper B; Annaert W
Amyloid; 2001 Jun; 8(2):124-42. PubMed ID: 11409035
[TBL] [Abstract][Full Text] [Related]
2. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Vassar R; Bennett BD; Babu-Khan S; Kahn S; Mendiaz EA; Denis P; Teplow DB; Ross S; Amarante P; Loeloff R; Luo Y; Fisher S; Fuller J; Edenson S; Lile J; Jarosinski MA; Biere AL; Curran E; Burgess T; Louis JC; Collins F; Treanor J; Rogers G; Citron M
Science; 1999 Oct; 286(5440):735-41. PubMed ID: 10531052
[TBL] [Abstract][Full Text] [Related]
3. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
Gandhi S; Refolo LM; Sambamurti K
J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
[TBL] [Abstract][Full Text] [Related]
4. Secretases as targets for the treatment of Alzheimer's disease: the prospects.
Dewachter I; Van Leuven F
Lancet Neurol; 2002 Nov; 1(7):409-16. PubMed ID: 12849363
[TBL] [Abstract][Full Text] [Related]
5. Regulation of APP cleavage by alpha-, beta- and gamma-secretases.
Nunan J; Small DH
FEBS Lett; 2000 Oct; 483(1):6-10. PubMed ID: 11033346
[TBL] [Abstract][Full Text] [Related]
6. BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics.
Roberds SL; Anderson J; Basi G; Bienkowski MJ; Branstetter DG; Chen KS; Freedman SB; Frigon NL; Games D; Hu K; Johnson-Wood K; Kappenman KE; Kawabe TT; Kola I; Kuehn R; Lee M; Liu W; Motter R; Nichols NF; Power M; Robertson DW; Schenk D; Schoor M; Shopp GM; Shuck ME; Sinha S; Svensson KA; Tatsuno G; Tintrup H; Wijsman J; Wright S; McConlogue L
Hum Mol Genet; 2001 Jun; 10(12):1317-24. PubMed ID: 11406613
[TBL] [Abstract][Full Text] [Related]
7. Generation of C-terminally truncated amyloid-beta peptides is dependent on gamma-secretase activity.
Beher D; Wrigley JD; Owens AP; Shearman MS
J Neurochem; 2002 Aug; 82(3):563-75. PubMed ID: 12153480
[TBL] [Abstract][Full Text] [Related]
8. L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity.
Shearman MS; Beher D; Clarke EE; Lewis HD; Harrison T; Hunt P; Nadin A; Smith AL; Stevenson G; Castro JL
Biochemistry; 2000 Aug; 39(30):8698-704. PubMed ID: 10913280
[TBL] [Abstract][Full Text] [Related]
9. Gamma-secretase: a catalyst of Alzheimer disease and signal transduction.
Li YM
Mol Interv; 2001 Oct; 1(4):198-207. PubMed ID: 14993342
[TBL] [Abstract][Full Text] [Related]
10. gamma-Secretase inhibitors as molecular probes of presenilin function.
Wolfe MS
J Mol Neurosci; 2001 Oct; 17(2):199-204. PubMed ID: 11816793
[TBL] [Abstract][Full Text] [Related]
11. [Pathogenesis of Alzheimer's disease: implications from amyloid research front].
Iwatsubo T
Rinsho Shinkeigaku; 2004 Nov; 44(11):768-70. PubMed ID: 15651286
[TBL] [Abstract][Full Text] [Related]
12. BACE-1 Inhibitors Targeting Alzheimer's Disease.
Monteiro KLC; Dos Santos Alcântara MG; Freire NML; Brandão EM; do Nascimento VL; Dos Santos Viana LM; de Aquino TM; da Silva-Júnior EF
Curr Alzheimer Res; 2023; 20(3):131-148. PubMed ID: 37309767
[TBL] [Abstract][Full Text] [Related]
13. Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease.
Huse JT; Doms RW
Mol Neurobiol; 2000; 22(1-3):81-98. PubMed ID: 11414282
[TBL] [Abstract][Full Text] [Related]
14. APP processing enzymes (secretases) as therapeutic targets: insights from the use of transgenics (Tgs) and transfected cells.
Marks N; Berg MJ
Neurochem Res; 2003 Jul; 28(7):1049-62. PubMed ID: 12737530
[TBL] [Abstract][Full Text] [Related]
15. The beta-secretase, BACE: a prime drug target for Alzheimer's disease.
Vassar R
J Mol Neurosci; 2001 Oct; 17(2):157-70. PubMed ID: 11816789
[TBL] [Abstract][Full Text] [Related]
16. The non-amyloidogenic pathway: structure and function of alpha-secretases.
Kojro E; Fahrenholz F
Subcell Biochem; 2005; 38():105-27. PubMed ID: 15709475
[TBL] [Abstract][Full Text] [Related]
17. A portrait of Alzheimer secretases--new features and familiar faces.
Esler WP; Wolfe MS
Science; 2001 Aug; 293(5534):1449-54. PubMed ID: 11520976
[TBL] [Abstract][Full Text] [Related]
18. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
[TBL] [Abstract][Full Text] [Related]
19. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.
Steiner H; Capell A; Leimer U; Haass C
Eur Arch Psychiatry Clin Neurosci; 1999; 249(6):266-70. PubMed ID: 10653281
[TBL] [Abstract][Full Text] [Related]
20. Failure of the interaction between presenilin 1 and the substrate of gamma-secretase to produce Abeta in insect cells.
Pitsi D; Kienlen-Campard P; Octave JN
J Neurochem; 2002 Oct; 83(2):390-9. PubMed ID: 12423249
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]