BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

304 related articles for article (PubMed ID: 11412113)

  • 1. In vitro reconstitution of recognition and activation complexes between interleukin-6 and gp130.
    Chow D; Ho J; Nguyen Pham TL; Rose-John S; Garcia KC
    Biochemistry; 2001 Jun; 40(25):7593-603. PubMed ID: 11412113
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Two different epitopes of the signal transducer gp130 sequentially cooperate on IL-6-induced receptor activation.
    Pflanz S; Kurth I; Grötzinger J; Heinrich PC; Müller-Newen G
    J Immunol; 2000 Dec; 165(12):7042-9. PubMed ID: 11120832
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex.
    Boulanger MJ; Chow DC; Brevnova EE; Garcia KC
    Science; 2003 Jun; 300(5628):2101-4. PubMed ID: 12829785
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor.
    Skiniotis G; Boulanger MJ; Garcia KC; Walz T
    Nat Struct Mol Biol; 2005 Jun; 12(6):545-51. PubMed ID: 15895091
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of the signal transducer glycoprotein 130 by both IL-6 and IL-11 requires two distinct binding epitopes.
    Kurth I; Horsten U; Pflanz S; Dahmen H; Küster A; Grötzinger J; Heinrich PC; Müller-Newen G
    J Immunol; 1999 Feb; 162(3):1480-7. PubMed ID: 9973404
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular mechanisms for viral mimicry of a human cytokine: activation of gp130 by HHV-8 interleukin-6.
    Boulanger MJ; Chow DC; Brevnova E; Martick M; Sandford G; Nicholas J; Garcia KC
    J Mol Biol; 2004 Jan; 335(2):641-54. PubMed ID: 14672670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The N-terminus of gp130 is critical for the formation of the high-affinity interleukin-6 receptor complex.
    Moritz RL; Ward LD; Tu GF; Fabri LJ; Ji H; Yasukawa K; Simpson RJ
    Growth Factors; 1999; 16(4):265-78. PubMed ID: 10427501
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The membrane proximal cytokine receptor domain of the human interleukin-6 receptor is sufficient for ligand binding but not for gp130 association.
    Ozbek S; Grötzinger J; Krebs B; Fischer M; Wollmer A; Jostock T; Müllberg J; Rose-John S
    J Biol Chem; 1998 Aug; 273(33):21374-9. PubMed ID: 9694899
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conservation of functional sites on interleukin-6 and implications for evolution of signaling complex assembly and therapeutic intervention.
    Veverka V; Baker T; Redpath NT; Carrington B; Muskett FW; Taylor RJ; Lawson AD; Henry AJ; Carr MD
    J Biol Chem; 2012 Nov; 287(47):40043-50. PubMed ID: 23027872
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus.
    Aoki Y; Narazaki M; Kishimoto T; Tosato G
    Blood; 2001 Nov; 98(10):3042-9. PubMed ID: 11698289
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interleukin-11 signals through the formation of a hexameric receptor complex.
    Barton VA; Hall MA; Hudson KR; Heath JK
    J Biol Chem; 2000 Nov; 275(46):36197-203. PubMed ID: 10948192
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A fusion protein of the gp130 and interleukin-6Ralpha ligand-binding domains acts as a potent interleukin-6 inhibitor.
    Ancey C; Küster A; Haan S; Herrmann A; Heinrich PC; Müller-Newen G
    J Biol Chem; 2003 May; 278(19):16968-72. PubMed ID: 12646580
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of an extracellular gp130 cytokine receptor signaling complex.
    Chow D; He X; Snow AL; Rose-John S; Garcia KC
    Science; 2001 Mar; 291(5511):2150-5. PubMed ID: 11251120
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions.
    Dahmen H; Horsten U; Küster A; Jacques Y; Minvielle S; Kerr IM; Ciliberto G; Paonessa G; Heinrich PC; Müller-Newen G
    Biochem J; 1998 May; 331 ( Pt 3)(Pt 3):695-702. PubMed ID: 9560294
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of amino acid residues of gp130 signal transducer and gp80 alpha receptor subunit that are involved in ligand binding and signaling by human herpesvirus 8-encoded interleukin-6.
    Li H; Nicholas J
    J Virol; 2002 Jun; 76(11):5627-36. PubMed ID: 11991991
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130.
    Lehmann U; Schmitz J; Weissenbach M; Sobota RM; Hortner M; Friederichs K; Behrmann I; Tsiaris W; Sasaki A; Schneider-Mergener J; Yoshimura A; Neel BG; Heinrich PC; Schaper F
    J Biol Chem; 2003 Jan; 278(1):661-71. PubMed ID: 12403768
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
    Bode JG; Schweigart J; Kehrmann J; Ehlting C; Schaper F; Heinrich PC; Häussinger D
    J Immunol; 2003 Jul; 171(1):257-66. PubMed ID: 12817006
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Influence of interleukin-6 (IL-6) dimerization on formation of the high affinity hexameric IL-6.receptor complex.
    Ward LD; Hammacher A; Howlett GJ; Matthews JM; Fabri L; Moritz RL; Nice EC; Weinstock J; Simpson RJ
    J Biol Chem; 1996 Aug; 271(33):20138-44. PubMed ID: 8702737
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Engineering human interleukin-6 to obtain variants with strongly enhanced bioactivity.
    Toniatti C; Cabibbo A; Sporena E; Salvati AL; Cerretani M; Serafini S; Lahm A; Cortese R; Ciliberto G
    EMBO J; 1996 Jun; 15(11):2726-37. PubMed ID: 8654370
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The interactions of the cytokine-binding homology region and immunoglobulin-like domains of gp130 with oncostatin M: implications for receptor complex formation.
    Staunton D; Hudson KR; Heath JK
    Protein Eng; 1998 Nov; 11(11):1093-102. PubMed ID: 9876932
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.