BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 11419027)

  • 1. Signal therapy for RAS-induced cancers in combination of AG 879 and PP1, specific inhibitors for ErbB2 and Src family kinases, that block PAK activation.
    He H; Hirokawa Y; Manser E; Lim L; Levitzki A; Maruta H
    Cancer J; 2001; 7(3):191-202. PubMed ID: 11419027
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An anti-Ras cancer potential of PP1, an inhibitor specific for Src family kinases: in vitro and in vivo studies.
    He H; Hirokawa Y; Levitzki A; Maruta H
    Cancer J; 2000; 6(4):243-8. PubMed ID: 11038144
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural analysis of the SH3 domain of beta-PIX and its interaction with alpha-p21 activated kinase (PAK).
    Mott HR; Nietlispach D; Evetts KA; Owen D
    Biochemistry; 2005 Aug; 44(33):10977-83. PubMed ID: 16101281
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of the SH3 domain of betaPIX in complex with a high affinity peptide from PAK2.
    Hoelz A; Janz JM; Lawrie SD; Corwin B; Lee A; Sakmar TP
    J Mol Biol; 2006 Apr; 358(2):509-22. PubMed ID: 16527308
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Signal therapy of human pancreatic cancer and NF1-deficient breast cancer xenograft in mice by a combination of PP1 and GL-2003, anti-PAK1 drugs (Tyr-kinase inhibitors).
    Hirokawa Y; Levitzki A; Lessene G; Baell J; Xiao Y; Zhu H; Maruta H
    Cancer Lett; 2007 Jan; 245(1-2):242-51. PubMed ID: 16540233
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The CDC42-specific inhibitor derived from ACK-1 blocks v-Ha-Ras-induced transformation.
    Nur-E-Kamal MS; Kamal JM; Qureshi MM; Maruta H
    Oncogene; 1999 Dec; 18(54):7787-93. PubMed ID: 10618719
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Control of PDGF-induced reactive oxygen species (ROS) generation and signal transduction in human lens epithelial cells.
    Chen KC; Zhou Y; Zhang W; Lou MF
    Mol Vis; 2007 Mar; 13():374-87. PubMed ID: 17392688
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biochemical characterization of the Cool (Cloned-out-of-Library)/Pix (Pak-interactive exchange factor) proteins.
    Baird D; Feng Q; Cerione RA
    Methods Enzymol; 2006; 406():58-69. PubMed ID: 16472649
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of activation of Pak1 kinase by membrane localization.
    Lu W; Mayer BJ
    Oncogene; 1999 Jan; 18(3):797-806. PubMed ID: 9989831
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Involvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyrene.
    Yoshii S; Tanaka M; Otsuki Y; Fujiyama T; Kataoka H; Arai H; Hanai H; Sugimura H
    Mol Cell Biol; 2001 Oct; 21(20):6796-807. PubMed ID: 11564864
    [TBL] [Abstract][Full Text] [Related]  

  • 11. alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase.
    Yoshii S; Tanaka M; Otsuki Y; Wang DY; Guo RJ; Zhu Y; Takeda R; Hanai H; Kaneko E; Sugimura H
    Oncogene; 1999 Oct; 18(41):5680-90. PubMed ID: 10523848
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lysophosphatidic acid stimulates p21-activated kinase in vascular smooth muscle cells.
    Schmitz U; Thömmes K; Beier I; Vetter H
    Biochem Biophys Res Commun; 2002 Mar; 291(3):687-91. PubMed ID: 11855845
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Vav transformation requires activation of multiple GTPases and regulation of gene expression.
    Palmby TR; Abe K; Karnoub AE; Der CJ
    Mol Cancer Res; 2004 Dec; 2(12):702-11. PubMed ID: 15634759
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rho family-associated kinases PAK1 and rock.
    Maruta H; Nheu TV; He H; Hirokawa Y
    Prog Cell Cycle Res; 2003; 5():203-10. PubMed ID: 14593714
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Src family kinase inhibitors block amphiregulin-mediated autocrine ErbB signaling in normal human keratinocytes.
    Kansra S; Stoll SW; Johnson JL; Elder JT
    Mol Pharmacol; 2005 Apr; 67(4):1145-57. PubMed ID: 15615697
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Delineation of the Cdc42/Rac-binding domain of p21-activated kinase.
    Thompson G; Owen D; Chalk PA; Lowe PN
    Biochemistry; 1998 May; 37(21):7885-91. PubMed ID: 9601050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction between the Helicobacter pylori CagA and alpha-Pix in gastric epithelial AGS cells.
    Baek HY; Lim JW; Kim H
    Ann N Y Acad Sci; 2007 Jan; 1096():18-23. PubMed ID: 17405911
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of ErbB2 receptor tyrosine kinase supports invasion of endothelial cells by Neisseria meningitidis.
    Hoffmann I; Eugène E; Nassif X; Couraud PO; Bourdoulous S
    J Cell Biol; 2001 Oct; 155(1):133-43. PubMed ID: 11581290
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Tyr-kinase inhibitor AG879, that blocks the ETK-PAK1 interaction, suppresses the RAS-induced PAK1 activation and malignant transformation.
    He H; Hirokawa Y; Gazit A; Yamashita Y; Mano H; Kawakami Y; Kawakami ; Hsieh CY; Kung HJ; Lessene G; Baell J; Levitzki A; Maruta H
    Cancer Biol Ther; 2004 Jan; 3(1):96-101. PubMed ID: 14726663
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides.
    Motoyama AB; Hynes NE; Lane HA
    Cancer Res; 2002 Jun; 62(11):3151-8. PubMed ID: 12036928
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.