These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

96 related articles for article (PubMed ID: 11421800)

  • 1. 2-Alkylthio-4-oxo-3-quinazolineacetonitriles and analogous thieno[3,2-d]pyrimidineacetonitriles: reaction with thiols via trapped thioimidates.
    Gütschow M; Powers JC
    J Org Chem; 2001 Jun; 66(13):4723-7. PubMed ID: 11421800
    [No Abstract]   [Full Text] [Related]  

  • 2. Discovery of a novel series of selective MMP inhibitors: identification of the gamma-sulfone-thiols.
    Freskos JN; Mischke BV; DeCrescenzo GA; Heintz R; Getman DP; Howard SC; Kishore NN; McDonald JJ; Munie GE; Rangwala S; Swearingen CA; Voliva C; Welsch DJ
    Bioorg Med Chem Lett; 1999 Apr; 9(7):943-8. PubMed ID: 10230616
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of novel 6-substituted quinazoline-2-thiols.
    Pulakhandam SK; Katari NK; Jonnalagadda SB
    Mol Divers; 2019 May; 23(2):351-360. PubMed ID: 30238392
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analogs of a 4-aminothieno[2,3-d]pyrimidine lead (QB13) as modulators of P-glycoprotein substrate specificity.
    Häcker HG; de la Haye A; Sterz K; Schnakenburg G; Wiese M; Gütschow M
    Bioorg Med Chem Lett; 2009 Nov; 19(21):6102-5. PubMed ID: 19783433
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of thieno[2,3-d]pyrimidin-2-ylmethanamine combinatorial library with four diversity points.
    Bogolubsky AV; Ryabukhin SV; Stetsenko SV; Chupryna AA; Volochnyuk DM; Tolmachev AA
    J Comb Chem; 2007; 9(4):661-7. PubMed ID: 17530808
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Macrocyclic BACE inhibitors: Optimization of a micromolar hit to nanomolar leads.
    Huang Y; Strobel ED; Ho CY; Reynolds CH; Conway KA; Piesvaux JA; Brenneman DE; Yohrling GJ; Moore Arnold H; Rosenthal D; Alexander RS; Tounge BA; Mercken M; Vandermeeren M; Parker MH; Reitz AB; Baxter EW
    Bioorg Med Chem Lett; 2010 May; 20(10):3158-60. PubMed ID: 20399652
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Microwave-assisted three-component synthesis of 7-aryl-2-alkylthio-4,7-dihydro-1,2,4-triazolo[1,5-a]-pyrimidine-6-carboxamides and their selective reduction.
    Chebanov VA; Muravyova EA; Desenko SM; Musatov VI; Knyazeva IV; Shishkina SV; Shishkin OV; Kappe CO
    J Comb Chem; 2006; 8(3):427-34. PubMed ID: 16677013
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isothiazolones; thiol-reactive inhibitors of cysteine protease cathepsin B and histone acetyltransferase PCAF.
    Wisastra R; Ghizzoni M; Maarsingh H; Minnaard AJ; Haisma HJ; Dekker FJ
    Org Biomol Chem; 2011 Mar; 9(6):1817-22. PubMed ID: 21267493
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and SAR of azolopyrimidines as potent and selective dipeptidyl peptidase-4 (DPP4) inhibitors for type 2 diabetes.
    Brigance RP; Meng W; Fura A; Harrity T; Wang A; Zahler R; Kirby MS; Hamann LG
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4395-8. PubMed ID: 20598534
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2-Cyano-pyrimidines: a new chemotype for inhibitors of the cysteine protease cathepsin K.
    Altmann E; Aichholz R; Betschart C; Buhl T; Green J; Irie O; Teno N; Lattmann R; Tintelnot-Blomley M; Missbach M
    J Med Chem; 2007 Feb; 50(4):591-4. PubMed ID: 17256925
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and antiallergy activity of 10-oxo-10H-pyrido[1,2-a]thieno[3,2-d]pyrimidines and 10-oxo-10H-pyrido[1,2-a]thieno[3,4-d]pyrimidines.
    Connor DT; Sorenson RJ; Cetenko WA; Kerbleski JJ; Tinney FJ
    J Med Chem; 1984 Apr; 27(4):528-30. PubMed ID: 6142956
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of substituted 4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazolines and 4-oxo-3,4-dihydroquinazoline-2-thioles.
    Ivachtchenko AV; Kovalenko SM; Drushlyak OG
    J Comb Chem; 2003; 5(6):775-88. PubMed ID: 14606805
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytosine analogues from substituted acetonitriles via Thorpe condensation.
    Barkin JL; Faust MD; Trenkle WC
    Org Lett; 2003 Sep; 5(18):3333-5. PubMed ID: 12943420
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors.
    Olimpieri F; Tambaro S; Fustero S; Lazzari P; Sanchez-Roselló M; Pani L; Volonterio A; Zanda M
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4715-9. PubMed ID: 19596577
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel thiol-based TACE inhibitors. Part 2: Rational design, synthesis, and SAR of thiol-containing aryl sulfones.
    Bandarage UK; Wang T; Come JH; Perola E; Wei Y; Rao BG
    Bioorg Med Chem Lett; 2008 Jan; 18(1):44-8. PubMed ID: 18054488
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important.
    Cai J; Fradera X; van Zeeland M; Dempster M; Cameron KS; Bennett DJ; Robinson J; Popplestone L; Baugh M; Westwood P; Bruin J; Hamilton W; Kinghorn E; Long C; Uitdehaag JC
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4507-10. PubMed ID: 20580231
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Superacid-promoted additions involving vinyl-substituted pyrimidines, quinoxalines, and quinazolines: mechanisms correlated to charge distributions.
    Zhang Y; Sheets MR; Raja EK; Boblak KN; Klumpp DA
    J Am Chem Soc; 2011 Jun; 133(22):8467-9. PubMed ID: 21548654
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 2-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)- and 2-(2,2-dioxo-1,4-dihydro-2H-2lambda6-benzo[1,2,6]thiadiazin-3-yl)-N-hydroxy-acetamides as potent and selective peptide deformylase inhibitors.
    Apfel C; Banner DW; Bur D; Dietz M; Hubschwerlen C; Locher H; Marlin F; Masciadri R; Pirson W; Stalder H
    J Med Chem; 2001 Jun; 44(12):1847-52. PubMed ID: 11384231
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of novel quinazolin-4(3H)-ones as inhibitors of thermolysin, the prototype of the M4 family of proteinases.
    Khan MT; Khan R; Wuxiuer Y; Arfan M; Ahmed M; Sylte I
    Bioorg Med Chem; 2010 Jun; 18(12):4317-27. PubMed ID: 20494587
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Establishment of the C-NO bond dissociation energy scale in solution and its application in analyzing the trend of NO transfer from C-nitroso compound to thiols.
    Li X; Deng H; Zhu XQ; Wang X; Liang H; Cheng JP
    J Org Chem; 2009 Jun; 74(12):4472-8. PubMed ID: 19453157
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.