334 related articles for article (PubMed ID: 11427550)
1. Identification of two different 14-alpha sterol demethylase-related genes (cyp51A and cyp51B) in Aspergillus fumigatus and other Aspergillus species.
Mellado E; Diaz-Guerra TM; Cuenca-Estrella M; Rodriguez-Tudela JL
J Clin Microbiol; 2001 Jul; 39(7):2431-8. PubMed ID: 11427550
[TBL] [Abstract][Full Text] [Related]
2. Aspergillus fumigatus CYP51 sequence: potential basis for fluconazole resistance.
Edlind TD; Henry KW; Metera KA; Katiyar SK
Med Mycol; 2001 Jun; 39(3):299-302. PubMed ID: 11446535
[TBL] [Abstract][Full Text] [Related]
3. Isolation and molecular characterisation of the gene encoding eburicol 14 alpha-demethylase (cYP51) from Penicillium italicum.
van Nistelrooy JG; van den Brink JM; van Kan JA; van Gorcom RF; de Waard MA
Mol Gen Genet; 1996 Apr; 250(6):725-33. PubMed ID: 8628233
[TBL] [Abstract][Full Text] [Related]
4. Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs.
Hargrove TY; Wawrzak Z; Lamb DC; Guengerich FP; Lepesheva GI
J Biol Chem; 2015 Sep; 290(39):23916-34. PubMed ID: 26269599
[TBL] [Abstract][Full Text] [Related]
5. Analysis of Cyp51 protein sequences shows 4 major Cyp51 gene family groups across fungi.
Celia-Sanchez BN; Mangum B; Brewer M; Momany M
G3 (Bethesda); 2022 Nov; 12(11):. PubMed ID: 36130263
[TBL] [Abstract][Full Text] [Related]
6. Three-dimensional models of 14α-sterol demethylase (Cyp51A) from Aspergillus lentulus and Aspergillus fumigatus: an insight into differences in voriconazole interaction.
Alcazar-Fuoli L; Cuesta I; Rodriguez-Tudela JL; Cuenca-Estrella M; Sanglard D; Mellado E
Int J Antimicrob Agents; 2011 Nov; 38(5):426-34. PubMed ID: 21871783
[TBL] [Abstract][Full Text] [Related]
7. Cloning and expression in Escherichia coli of the obtusifoliol 14 alpha-demethylase of Sorghum bicolor (L.) Moench, a cytochrome P450 orthologous to the sterol 14 alpha-demethylases (CYP51) from fungi and mammals.
Bak S; Kahn RA; Olsen CE; Halkier BA
Plant J; 1997 Feb; 11(2):191-201. PubMed ID: 9076987
[TBL] [Abstract][Full Text] [Related]
8. Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs.
Mellado E; Garcia-Effron G; Alcazar-Fuoli L; Cuenca-Estrella M; Rodriguez-Tudela JL
Antimicrob Agents Chemother; 2004 Jul; 48(7):2747-50. PubMed ID: 15215142
[TBL] [Abstract][Full Text] [Related]
9. Point Mutations in the 14-α Sterol Demethylase Cyp51A or Cyp51C Could Contribute to Azole Resistance in
Lucio J; Gonzalez-Jimenez I; Rivero-Menendez O; Alastruey-Izquierdo A; Pelaez T; Alcazar-Fuoli L; Mellado E
Genes (Basel); 2020 Oct; 11(10):. PubMed ID: 33080784
[TBL] [Abstract][Full Text] [Related]
10. Point Mutation or Overexpression of Aspergillus fumigatus
Handelman M; Meir Z; Scott J; Shadkchan Y; Liu W; Ben-Ami R; Amich J; Osherov N
Antimicrob Agents Chemother; 2021 Sep; 65(10):e0125221. PubMed ID: 34310208
[TBL] [Abstract][Full Text] [Related]
11. Modeling and interactions of Aspergillus fumigatus lanosterol 14-alpha demethylase 'A' with azole antifungals.
Gollapudy R; Ajmani S; Kulkarni SA
Bioorg Med Chem; 2004 Jun; 12(11):2937-50. PubMed ID: 15142553
[TBL] [Abstract][Full Text] [Related]
12. Effect of DMI-resistance mechanisms on cross-resistance patterns, fitness parameters and aflatoxin production in Aspergillus parasiticus Speare.
Doukas EG; Markoglou AN; Vontas JG; Ziogas BN
Fungal Genet Biol; 2012 Oct; 49(10):792-801. PubMed ID: 22906850
[TBL] [Abstract][Full Text] [Related]
13. CYP51 Paralogue Structure Is Associated with Intrinsic Azole Resistance in Fungi.
Van Rhijn N; Bromley M; Richardson M; Bowyer P
mBio; 2021 Oct; 12(5):e0194521. PubMed ID: 34607450
[TBL] [Abstract][Full Text] [Related]
14. cyp51A-based mechanism of azole resistance in Aspergillus fumigatus: Illustration by a new 3D Structural Model of Aspergillus fumigatus CYP51A protein.
Liu M; Zheng N; Li D; Zheng H; Zhang L; Ge H; Liu W
Med Mycol; 2016 May; 54(4):400-8. PubMed ID: 26768370
[TBL] [Abstract][Full Text] [Related]
15. Molecular characterisation of cyp51A and cyp51B genes coding for P450 14alpha-lanosterol demethylases A (CYP51Ap) and B (CYP51Bp) from voriconazole-resistant laboratory isolates of Aspergillus flavus.
Krishnan-Natesan S; Chandrasekar PH; Alangaden GJ; Manavathu EK
Int J Antimicrob Agents; 2008 Dec; 32(6):519-24. PubMed ID: 18775650
[TBL] [Abstract][Full Text] [Related]
16. A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus.
Diaz-Guerra TM; Mellado E; Cuenca-Estrella M; Rodriguez-Tudela JL
Antimicrob Agents Chemother; 2003 Mar; 47(3):1120-4. PubMed ID: 12604551
[TBL] [Abstract][Full Text] [Related]
17. Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (sterol 14α-demethylase) doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B.
Martel CM; Parker JE; Warrilow AG; Rolley NJ; Kelly SL; Kelly DE
Antimicrob Agents Chemother; 2010 Nov; 54(11):4920-3. PubMed ID: 20733045
[TBL] [Abstract][Full Text] [Related]
18. Crystal Structure of the New Investigational Drug Candidate VT-1598 in Complex with Aspergillus fumigatus Sterol 14α-Demethylase Provides Insights into Its Broad-Spectrum Antifungal Activity.
Hargrove TY; Garvey EP; Hoekstra WJ; Yates CM; Wawrzak Z; Rachakonda G; Villalta F; Lepesheva GI
Antimicrob Agents Chemother; 2017 Jul; 61(7):. PubMed ID: 28461309
[TBL] [Abstract][Full Text] [Related]
19. Resistance to itraconazole in Aspergillus nidulans and Aspergillus fumigatus is conferred by extra copies of the A. nidulans P-450 14alpha-demethylase gene, pdmA.
Osherov N; Kontoyiannis DP; Romans A; May GS
J Antimicrob Chemother; 2001 Jul; 48(1):75-81. PubMed ID: 11418514
[TBL] [Abstract][Full Text] [Related]
20. Ergosterol biosynthesis pathway in Aspergillus fumigatus.
Alcazar-Fuoli L; Mellado E; Garcia-Effron G; Lopez JF; Grimalt JO; Cuenca-Estrella JM; Rodriguez-Tudela JL
Steroids; 2008 Mar; 73(3):339-47. PubMed ID: 18191972
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]