BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 11427727)

  • 1. Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation.
    Poltoratsky V; Woo CJ; Tippin B; Martin A; Goodman MF; Scharff MD
    Proc Natl Acad Sci U S A; 2001 Jul; 98(14):7976-81. PubMed ID: 11427727
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.
    Schrader CE; Linehan EK; Ucher AJ; Bertocci B; Stavnezer J
    DNA Repair (Amst); 2013 Dec; 12(12):1087-93. PubMed ID: 24084171
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Normal immunoglobulin gene somatic hypermutation in Pol kappa-Pol iota double-deficient mice.
    Shimizu T; Azuma T; Ishiguro M; Kanjo N; Yamada S; Ohmori H
    Immunol Lett; 2005 May; 98(2):259-64. PubMed ID: 15860226
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.
    Faili A; Aoufouchi S; Flatter E; Guéranger Q; Reynaud CA; Weill JC
    Nature; 2002 Oct; 419(6910):944-7. PubMed ID: 12410315
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human DNA polymerase-eta, an A-T mutator in somatic hypermutation of rearranged immunoglobulin genes, is a reverse transcriptase.
    Franklin A; Milburn PJ; Blanden RV; Steele EJ
    Immunol Cell Biol; 2004 Apr; 82(2):219-25. PubMed ID: 15061777
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The absence of DNA polymerase kappa does not affect somatic hypermutation of the mouse immunoglobulin heavy chain gene.
    Shimizu T; Shinkai Y; Ogi T; Ohmori H; Azuma T
    Immunol Lett; 2003 May; 86(3):265-70. PubMed ID: 12706529
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recombinase-mediated cassette exchange as a novel method to study somatic hypermutation in Ramos cells.
    Baughn LB; Kalis SL; MacCarthy T; Wei L; Fan M; Bergman A; Scharff MD
    mBio; 2011; 2(5):. PubMed ID: 21990614
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genesis of the strand-biased signature in somatic hypermutation of rearranged immunoglobulin variable genes.
    Steele EJ; Franklin A; Blanden RV
    Immunol Cell Biol; 2004 Apr; 82(2):209-18. PubMed ID: 15061776
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation.
    Zan H; Shima N; Xu Z; Al-Qahtani A; Evinger Iii AJ; Zhong Y; Schimenti JC; Casali P
    EMBO J; 2005 Nov; 24(21):3757-69. PubMed ID: 16222339
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ongoing somatic hypermutation of the rearranged VH but not of the V-lambda gene in EBV-transformed rheumatoid factor-producing lymphoblastoid cell line.
    Chezar I; Lobel-Lavi L; Steinitz M; Laskov R
    Mol Immunol; 2008 Nov; 46(1):80-90. PubMed ID: 18718665
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.
    Masuda K; Ouchida R; Takeuchi A; Saito T; Koseki H; Kawamura K; Tagawa M; Tokuhisa T; Azuma T; O-Wang J
    Proc Natl Acad Sci U S A; 2005 Sep; 102(39):13986-91. PubMed ID: 16172387
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes.
    Maul RW; MacCarthy T; Frank EG; Donigan KA; McLenigan MP; Yang W; Saribasak H; Huston DE; Lange SS; Woodgate R; Gearhart PJ
    J Exp Med; 2016 Aug; 213(9):1675-83. PubMed ID: 27455952
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate.
    Ruiz JF; Lucas D; García-Palomero E; Saez AI; González MA; Piris MA; Bernad A; Blanco L
    Nucleic Acids Res; 2004; 32(19):5861-73. PubMed ID: 15520469
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation.
    Zan H; Cerutti A; Dramitinos P; Schaffer A; Li Z; Casali P
    J Immunol; 1999 Mar; 162(6):3437-47. PubMed ID: 10092799
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation.
    McDonald JP; Frank EG; Plosky BS; Rogozin IB; Masutani C; Hanaoka F; Woodgate R; Gearhart PJ
    J Exp Med; 2003 Aug; 198(4):635-43. PubMed ID: 12925679
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data.
    Cui A; Di Niro R; Vander Heiden JA; Briggs AW; Adams K; Gilbert T; O'Connor KC; Vigneault F; Shlomchik MJ; Kleinstein SH
    J Immunol; 2016 Nov; 197(9):3566-3574. PubMed ID: 27707999
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Burkitt's lymphoma is a malignancy of mature B cells expressing somatically mutated V region genes.
    Klein U; Klein G; Ehlin-Henriksson B; Rajewsky K; Küppers R
    Mol Med; 1995 Jul; 1(5):495-505. PubMed ID: 8529116
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions.
    Saribasak H; Maul RW; Cao Z; Yang WW; Schenten D; Kracker S; Gearhart PJ
    J Exp Med; 2012 Jun; 209(6):1075-81. PubMed ID: 22615128
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA repair in antibody somatic hypermutation.
    Casali P; Pal Z; Xu Z; Zan H
    Trends Immunol; 2006 Jul; 27(7):313-21. PubMed ID: 16737852
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of Ig gene somatic hypermutation in the absence of activation-induced cytidine deaminase.
    Longo NS; Satorius CL; Plebani A; Durandy A; Lipsky PE
    J Immunol; 2008 Jul; 181(2):1299-306. PubMed ID: 18606684
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.